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CUSP project aims to reduce ventilator-associated pneumonia in hospitals

UHC announced its selection as a coordinating entity for a 3-year, $7.3 million contract from the Agency for Healthcare Research and Quality that has been awarded to the Johns Hopkins Armstrong Institute for Patient Safety and Quality to reduce ventilator-associated pneumonia in hospitals.

10 Dec 2013

Pemetrexed, paclitaxel regimens equally effective in NSCLC

PointBreak trial results suggest that pemetrexed- and paclitaxel-based chemotherapy offer comparable survival outcomes and tolerability for patients with advanced nonsquamous non-small-cell lung cancer (NSCLC) but with differing toxicity profiles.

10 Dec 2013

Reverse Medical gets FDA clearance to market MVP-5 Micro Vascular Plug system in the US

Reverse Medical Corporation today announced FDA clearance for US commercialization of their MVP-5 Micro Vascular Plug system for peripheral vessel embolization, and the first US clinical case. The MVP-5 system is indicated for use to obstruct or reduce the rate of blood flow in the peripheral vasculature, in vessels measuring between 3.0 and 5.0 mm.

10 Dec 2013

First Edition: December 10, 2103

Today's early morning highlights from the major news organizations, including reports about how health law advocates are developing new messaging strategies.

10 Dec 2013

Virginia Health Information publishes 2013 Health Care Pricing Report

As the price of health care increases, employers struggle to control costs and maintain employee health care benefits. One strategy increases the amount employees pay in deductibles or co-pays. With more money coming out of their pockets, information on the costs of care can help consumers make more informed health care purchasing decisions.

10 Dec 2013

Methodist Health System joins with IBM Watson and MD Buyline to enable better patient care

Methodist Health System, a premier healthcare provider in the Dallas-Fort Worth area, will leverage MD Buyline's Hippocrates powered by IBM Watson (a cognitive computing application) in its hospitals to enable better patient care, satisfaction and outcomes through more informed decision making.

10 Dec 2013

CRC gets accreditation under EUCROF Quality Mark for Early Phase Units scheme

Centro Ricerche Cliniche di Verona, a leading Early Phase Clinical Research facility, today announced that it has become the first organization to be accredited under a new scheme of quality certification conducted by EUCROF (European CROs Federation).

10 Dec 2013

ACoS Commission on Cancer, PHCQA partner to make PA cancer quality data available to public

The American College of Surgeons Commission on Cancer has joined with the Pennsylvania Health Care Quality Alliance to make cancer quality data from participating Pennsylvania hospitals available to the public. The initiative, which is the first of its kind in the U.S., will include data from 72 percent (52 programs) of all CoC-accredited cancer programs in Pennsylvania.

10 Dec 2013

Epilepsy experts discuss on new NTI definition, bioequivalence guidelines at AES annual meeting

For several years, epilepsy practitioners have questioned the U.S. Food and Drug Administration's definition of bioequivalence as it applies to narrow therapeutic index drugs, such as those used for epilepsy. In response to these concerns, the FDA has sponsored 3 studies of antiepileptic drugs and also convened an advisory board to help determine which drugs are NTI.

10 Dec 2013

Many Americans still tend to avoid addressing own end-of-life issues

During the past two decades, high-profile legal cases surrounding end-of-life decisions have received widespread attention in the United States, prompting increased media focus and numerous debates on the subject.

10 Dec 2013

State highlights: Union, Calif. Hospital Assn. at odds over organization, ballot issues; Ind. hospital cuts worry nurses; N.C. Medicaid overhaul changes

Duane Dauner, president of the California Hospital Assn., emailed the group's board in September with a warning: The leader of the state's largest health care workers' union had told him that if hospitals did not pave the way for the organizing of 20,000 workers, the union would launch ballot measures taking aim at hospital pricing and executive pay. But negotiations on organizing agreements between the two sides stalled. In November, the union, SEIU-United Healthcare Workers West, filed two initiatives for the 2014 ballot that would limit hospital prices and cap executive compensation at nonprofit hospitals (Mason, 12/6).

10 Dec 2013

Viewpoints: Optimism about Obamacare; 834 errors; can-you-keep-your-doctor debate

This was the week when liberals decided that it was safe to feel optimistic about Obamacare again. ... A worst-case scenario, in which the website remained unusable well into the new year, seems to have been averted, and with it the danger that insurers or Congressional Democrats would begin to bail on Obamacare entirely.

10 Dec 2013

Researchers develop new drug-eluting contact lens for prolonged delivery of glaucoma medication

For nearly half a century, contact lenses have been proposed as a means of ocular drug delivery that may someday replace eye drops, but achieving controlled drug release has been a significant challenge.

10 Dec 2013

Scientists devise method to measure forces in 3D tissues, living embryos

As embryonic tissue develops, cells push and pull on each other, and they must do so correctly for the tissue to develop properly. Now scientists at Harvard University have devised the first method to measure these forces in three-dimensional (3D) tissues and living embryos.

10 Dec 2013

Drugs that enhance oxidative stress kill rhabdomyosarcoma tumor cells

Drugs that enhance a process called oxidative stress were found to kill rhabdomyosarcoma tumor cells growing in the laboratory and possibly bolstered the effectiveness of chemotherapy against this aggressive tumor of muscle and other soft tissue. The findings are the latest from the St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project and appear in the December 9 edition of the scientific journal Cancer Cell.

10 Dec 2013

Alnylam presents new pre-clinical data with ALN-AT3 for treatment of hemophilia and RBD

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has presented new pre-clinical data with ALN-AT3, a subcutaneously administered RNAi therapeutic targeting antithrombin (AT) for the treatment of hemophilia and rare bleeding disorders (RBD), at the 55th Annual Meeting of the American Society of Hematology (ASH) held December 7 - 10, 2013 in New Orleans.

10 Dec 2013

Acetylon announces positive preclinical data of ricolinostat (ACY-1215) in models of lymphoma

Acetylon Pharmaceuticals, Inc., the leader in the development of selective histone deacetylase (HDAC) inhibitors for enhanced therapeutic outcomes, announced that positive preclinical data of selective HDAC6 inhibitor, ricolinostat (ACY-1215), in models of lymphoma were presented today in an oral presentation by Dr. Jennifer Amengual, Assistant Professor of Medicine & Experimental Therapeutics, Columbia University Medical Center.

10 Dec 2013

New drug that blocks defective gene can arrest Waldenstrom's Macroglobulinemia in animal models

In nearly one-third of patients with Waldenstrom's Macroglobulinemia, a specific genetic mutation switches on the disease, and a new drug that blocks the defective gene can arrest the disease in animal models, researchers at Dana-Farber Cancer Institute and allied institutions will report at the 2013 annual meeting of the American Society of Hematology.

10 Dec 2013

Orthogonal design to sift optimal parameter of Neiguan acupuncture

The individual difference and non-repeatability in acupuncture have not only restricted the development of acupuncture, but have also affected the specificity of acupoints.

10 Dec 2013

European study investigates high blood pressure drug for treating Alzheimer's patients

An extensive European study is currently investigating whether a drug used to treat high blood pressure may also help patients with Alzheimer's disease. The EU is investing almost 6 million euros on the project, in which Sahlgrenska Academy and Sahlgrenska University Hospital are responsible for Sweden's contribution.

10 Dec 2013

Hospital News and Research

CUSP project aims to reduce ventilator-associated pneumonia in hospitals

Pemetrexed, paclitaxel regimens equally effective in NSCLC

Reverse Medical gets FDA clearance to market MVP-5 Micro Vascular Plug system in the US

First Edition: December 10, 2103

Virginia Health Information publishes 2013 Health Care Pricing Report

Methodist Health System joins with IBM Watson and MD Buyline to enable better patient care

CRC gets accreditation under EUCROF Quality Mark for Early Phase Units scheme

ACoS Commission on Cancer, PHCQA partner to make PA cancer quality data available to public

Epilepsy experts discuss on new NTI definition, bioequivalence guidelines at AES annual meeting

Many Americans still tend to avoid addressing own end-of-life issues

State highlights: Union, Calif. Hospital Assn. at odds over organization, ballot issues; Ind. hospital cuts worry nurses; N.C. Medicaid overhaul changes

Viewpoints: Optimism about Obamacare; 834 errors; can-you-keep-your-doctor debate

Researchers develop new drug-eluting contact lens for prolonged delivery of glaucoma medication

Scientists devise method to measure forces in 3D tissues, living embryos

Drugs that enhance oxidative stress kill rhabdomyosarcoma tumor cells

Alnylam presents new pre-clinical data with ALN-AT3 for treatment of hemophilia and RBD

Acetylon announces positive preclinical data of ricolinostat (ACY-1215) in models of lymphoma

New drug that blocks defective gene can arrest Waldenstrom's Macroglobulinemia in animal models

Orthogonal design to sift optimal parameter of Neiguan acupuncture

European study investigates high blood pressure drug for treating Alzheimer's patients

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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