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State highlights: Caremark to pay MassHealth $2.6M after not reimbursing claims; Ore. bill would force lawmakers on to state insurance exchange

A selection of health policy stories from Massachusetts, Oregon, Kansas and North Carolina.

5 Dec 2013

New study provides novel stem cell based, tissue engineered construct which can repair damaged bone

Researchers at the Department of Orthopaedics, of the Second Affiliated Hospital of Xi'an Jiaotong University Health Science Center, led by Dr. Kunzheng Wang and Dr. Pei Yang have developed a novel biomimetic tissue engineered bone graft based on rabbit adipose derived stem cells (rASCs), collagen I and a porous beta-tricalcium phosphate (β-TCP) scaffold.

5 Dec 2013

VTT receives innovation prize for technological development work behind allergy vaccine

The European Association of Research and Technology Organisations EARTO has awarded VTT Technical Research Centre of Finland an innovation prize for the technological development work behind allergy vaccine.

5 Dec 2013

Neurosurgery in Parkinson's disease: Social adjustment, quality of life and coping strategies

Subthalamic nucleus deep brain stimulation can significantly improve the motor features of the Parkinson's disease in carefully selected patients. However, effects of subthalamic nucleus deep brain stimulation on the social adjustment, coping strategies and mental health-related quality of life of these patients remain unclear.

5 Dec 2013

TLR4 antibody-mediated signaling system in apoptosis of hippocampal neurons

Toll-like receptor 4 (TLR4) antibody, protein kinase B (AKT) inhibitor, LY 294002, and glycogen synthase kinase 3β (GSK-3β) inhibitor, LiCl, were used by Yu He and colleagues from Nantong University, China to attenuate or augment the effects of the TLR4-phosphatidylinositol 3 kinase (PI3K)/AKT-GSK-3β signaling pathway so as to identify the participation of this signaling system in the apoptosis of hippocampal neurons.

5 Dec 2013

TB vaccine may help prevent multiple sclerosis

A vaccine used to prevent tuberculosis in other parts of the world may help prevent multiple sclerosis in people who show the beginning signs of the disease, according to a new study published in the December 4, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

5 Dec 2013

Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

In an effort to lower medical costs, identify patients at risk for injury, and speed patient recovery, scientists will attempt to identify a molecular signal that indicates severity of brain-injury during a $4 million, five-year federal grant to Barrow Neurological Institute at St. Joseph's Hospital and Medical Center, Phoenix Children's Hospital and the Translational Genomics Research Institute (TGen).

5 Dec 2013

New research offers fresh insights to drug designers searching for better pain treatments

In a technical tour de force, UC San Francisco scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat.

5 Dec 2013

BIDMC study shows carbon monoxide may have a role to play in treating cancer

In recent years, research has suggested that carbon monoxide, the highly toxic gas emitted from auto exhausts and faulty heating systems, can be used to treat certain inflammatory medical conditions. Now a study led by a research team at Beth Israel Deaconess Medical Center (BIDMC) shows for the first time that carbon monoxide may also have a role to play in treating cancer.

4 Dec 2013

Tet1 helps erase epigenetic imprints from genome ahead of egg, sperm development

A protein called Tet1 is partly responsible for giving primordial germ cells a clean epigenetic slate before developing into sperm and egg cells, according to a new study by researchers at Boston Children's Hospital.

4 Dec 2013

Bipolar-specific disease management gives good returns

Diagnostic-specific management of bipolar II disorder is associated with significant clinical improvements, show findings that support the need for greater recognition of the condition.

4 Dec 2013

Lung cancer is costliest cancer in European Union

The total cost of cancer care across the European Union was an estimated € 126 billion in 2009, with lung cancer having the highest cost, at 15% of the total.

4 Dec 2013

Depression during pregnancy may affect child's mental health

Depression is a serious mental illness that has many negative consequences for sufferers. But depression among pregnant women may also have an impact on their developing babies.

4 Dec 2013

Skylight's Seventh Annual Client Conference recognizes 35 hospitals for excellence

Healthcare professionals from leading acute care, specialty, academic, and pediatric hospitals gathered at the Hotel Del Coronado Nov. 20-22 for Skylight's Seventh Annual Client Conference.

4 Dec 2013

Electronic informational technologies provide better means of transparency in health care costs

-The "shroud of secrecy" once draped across private health care service costs could be lifted with innovative information technologies, Princeton University professor Uwe Reinhardt wrote in a review published by the Journal of the American Medical Association (JAMA).

4 Dec 2013

Diversity essential for brain's ability to localize sounds

The ability to localize the source of sound is important for navigating the world and for listening in noisy environments like restaurants, an action that is particularly difficult for elderly or hearing impaired people.

4 Dec 2013

Researchers analyze protective effects of mild hypothermia on CNS injuries

There are few data on the effectiveness and mechanism underlying mild hypothermia in the treatment of central nervous system injuries. Therefore, there is a need to investigate the potentially beneficial effects of mild hypothermia on central nervous system injuries.

4 Dec 2013

Smoking and obesity increase odds of early breast implant loss

New research findings published in the December issue of the Journal of the American College of Surgeons confirm that factors such as smoking and obesity increase the odds of early implant loss in women who undergo mastectomy and immediate breast reconstruction with implants. Additionally, the study authors propose a unique risk-scoring tool that allows surgeons to better counsel patients preoperatively about their predicted risk for complications.

4 Dec 2013

Sympathetic skin response test assesses autonomic nerve functions in patients with spinal cord injury

Neurological functions following spinal cord injury have generally been assessed using the American Spinal Injury Association (ASIA) impairment scale.

4 Dec 2013

Philanthropist pledges $5M to fund new endowed chair in Alzheimer's disease research at Keck School

Los Angeles residents Selim Zilkha and Mary Hayley are raising the stakes in the fight against Alzheimer's disease, the only cause of death among the top 10 in the United States that cannot currently be prevented, cured or slowed.

4 Dec 2013

Hospital News and Research

State highlights: Caremark to pay MassHealth $2.6M after not reimbursing claims; Ore. bill would force lawmakers on to state insurance exchange

New study provides novel stem cell based, tissue engineered construct which can repair damaged bone

VTT receives innovation prize for technological development work behind allergy vaccine

Neurosurgery in Parkinson's disease: Social adjustment, quality of life and coping strategies

TLR4 antibody-mediated signaling system in apoptosis of hippocampal neurons

TB vaccine may help prevent multiple sclerosis

Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

New research offers fresh insights to drug designers searching for better pain treatments

BIDMC study shows carbon monoxide may have a role to play in treating cancer

Tet1 helps erase epigenetic imprints from genome ahead of egg, sperm development

Bipolar-specific disease management gives good returns

Lung cancer is costliest cancer in European Union

Depression during pregnancy may affect child's mental health

Skylight's Seventh Annual Client Conference recognizes 35 hospitals for excellence

Electronic informational technologies provide better means of transparency in health care costs

Diversity essential for brain's ability to localize sounds

Researchers analyze protective effects of mild hypothermia on CNS injuries

Smoking and obesity increase odds of early breast implant loss

Sympathetic skin response test assesses autonomic nerve functions in patients with spinal cord injury

Philanthropist pledges $5M to fund new endowed chair in Alzheimer's disease research at Keck School

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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