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FDA approves OLYSIO (simeprevir) for treatment of chronic hepatitis C infection

Janssen Therapeutics, Division of Janssen Products, LP, announced today the U.S. Food and Drug Administration has approved OLYSIO (simeprevir), an NS3/4A protease inhibitor, for the treatment of chronic hepatitis C infection as part of an antiviral treatment regimen in combination with pegylated interferon and ribavirin in genotype 1 infected adults with compensated liver disease, including cirrhosis.

23 Nov 2013

Novel drug combats psychosis in Parkinson’s disease

The non-dopaminergic drug pimavanserin reduces psychotic symptoms in patients with Parkinson’s disease without worsening motor function, shows a randomized trial.

22 Nov 2013

Patient Safety Technologies announces closing of $5 million senior secured term loan

Patient Safety Technologies, Inc. today announced the closing of a $5 million senior secured term loan. At close, $4 million of the term loan was funded. The Company has the ability to draw an incremental $1 million under the term loan, subject to certain conditions. The five-year term loan matures in 2018 and bears interest at 13% per annum.

22 Nov 2013

Sinai Hospital reports results from Phase 2a trial of apo A-I infusion therapy CSL112

Researchers from the Sinai Center for Thrombosis Research presented findings from a Phase 2a trial substudy that examined the antiplatelet effects of CSL112, a novel apolipoprotein A-I (apo A-I) infusion therapy, at the American Heart Association 2013 Scientific Sessions.

22 Nov 2013

Genetic diagnostic test for inherited eye diseases now available from Mass. Eye and Ear

The Massachusetts Eye and Ear/Harvard Medical School Department of Ophthalmology today announced the availability of a comprehensive genetic diagnostic test for inherited eye diseases.

22 Nov 2013

High court's 'alarming' move on abortion; tragic attack in Virginia points to needs in mental health services; a better way to reduce hospital readmissions

In an alarming 5-to-4 ruling, the Supreme Court turned away an emergency application to block a new Texas law that is impeding access to safe and legal abortion care in the state. The ruling leaves in place an order by the United States Court of Appeals for the Fifth Circuit that allowed the law go into effect while it considers an appeal (11/20).

22 Nov 2013

Research report focuses on the impact of real-time cost information within a primary care

Health care costs continue to go up, and physicians control more than 80 percent of those costs. Could providing physicians with real-time information about the cost of what they order help to restrain excessive testing? This is the question addressed in an article- in the Journal of General Internal Medicine-, published by Springer. The research project was led by Daniel Horn of the Massachusetts General Hospital's Division of General Medicine in the US, and is among the first to focus on the impact that the passive display of real-time laboratory costs can have within a primary care, non-academic setting.

22 Nov 2013

First molecular test developed to detect eosinophilic esophagitis

Researchers at Cincinnati Children's Hospital Medical Center have developed the first molecular test to diagnose eosinophilic esophagitis, a chronic upper gastrointestinal disorder. The incidence of EoE has skyrocketed since it was first characterized two decades ago.

22 Nov 2013

Scientists hope to find new treatments for traumatic brain injury

In the most wide-reaching project of its kind, scientists at the University of Texas Medical Branch are expanding their research on traumatic brain injury, examining its progressive, chronic effects on the body in hopes of treating its immediate and long-term consequences. The project is funded by a three-year, $9 million grant from The Moody Foundation of Galveston.

22 Nov 2013

New NIH grant to help Chicago Stroke Trials Consortium accelerate treatment for stroke

A new network dedicated to advancing research and therapies for stroke is forming in Chicago thanks to $2 million in grants from the National Institutes of Health. The Chicago Stroke Trials Consortium is a partnership among Northwestern Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, John H. Stroger Jr. Hospital, Loyola University Medical Center, Rehabilitation Institute of Chicago, Rush University Medical Center, and University of Chicago Medicine that will build an infrastructure to support clinical trials for stroke prevention, treatment and recovery. Northwestern University will be the regional coordinating center for the consortium and administer the project over the next five years.

22 Nov 2013

Air quality forecast play an increasing role in mitigating health risk

As the link between air pollution and several illnesses has been established, air quality forecast will play an increasing role in mitigating health risk.

22 Nov 2013

CKD children with lower socio-economic status less likely to grow to normal height ranges

Even with more prescriptions for growth hormone, children and adolescents with chronic kidney disease were less likely to grow to normal height ranges if they came from lower-income families, according to research funded by the National Institutes of Health. Results from the Chronic Kidney Disease in Children Study are published in the December issue of the American Journal of Kidney Diseases and online today at http://www.ajkd.org.

22 Nov 2013

High knowledge about HIV and risky sexual activity does not make teens more likely to get tested for HIV

Having high knowledge about HIV and engaging in risky sexual activity do not make high-school-aged teens more likely to get tested for HIV. Those are the findings of a new study by researchers at Montefiore Medical Center and Albert Einstein College of Medicine of Yeshiva University.

22 Nov 2013

Communicating with partners about parenting and HIV helps young people

A team from Royal Holloway University and St. Mary's Hospital, London, interviewed young people aged 18-23 who had transmitted HIV from their mothers - known as 'perinatally acquired HIV' (PAH). Previously most of these children would have died in childhood, but medication in the UK, means they are surviving into early adulthood.

22 Nov 2013

Study shows relative increase of 322% for severe pre-eclampsia

A latest study by researchers at the Mailman School of Public Health and Columbia University Medical Center reports that pre-eclampsia, characterized by an elevation in the blood pressure and excess protein in the urine of pregnant women, has a 1.5-fold to 2-fold higher incidence in first pregnancies. The condition, which causes complications in approximately 3-6% of all pregnancies, is also associated with high risks of preterm delivery, intrauterine growth restriction, placental abruption, and perinatal mortality. Findings are published online in the British Medical Journal.

22 Nov 2013

New tool provides first comprehensive guide to optimize ostomy management

Nurses caring for ostomy patients will now be equipped with an essential new tool that provides them with the first comprehensive guide to optimize ostomy management and enhance patient safety.

22 Nov 2013

QoL, BMI predict exacerbations in Japanese COPD patients

Analysis of a cohort of Japanese chronic obstructive pulmonary disease patients with a low exacerbation frequency shows that low body mass index and poor health-related quality of life independently predict flare ups of the disease.

21 Nov 2013

Conversion from psychotic depression to bipolar disorder explored

Danish researchers have identified a range of characteristics in people with psychotic depression that predict an increased risk for conversion to bipolar disorder.

21 Nov 2013

Keeping active reduces women’s Crohn’s risk

Regular exercise protects women against the development of Crohn’s disease, reveals research published in the BMJ.

21 Nov 2013

Antibiotic resistance holds stable in U.S. children's hospitals

Two studies published in the December issue of Infection Control and Hospital Epidemiology show antibiotic resistance patterns for children have held stable over a seven-year period and surgical patients in U.S. children's hospitals account for 43 percent of all antibiotic use in children's hospitals, presenting an opportunity for targeted intervention.

21 Nov 2013

Hospital News and Research

FDA approves OLYSIO (simeprevir) for treatment of chronic hepatitis C infection

Novel drug combats psychosis in Parkinson’s disease

Patient Safety Technologies announces closing of $5 million senior secured term loan

Sinai Hospital reports results from Phase 2a trial of apo A-I infusion therapy CSL112

Genetic diagnostic test for inherited eye diseases now available from Mass. Eye and Ear

High court's 'alarming' move on abortion; tragic attack in Virginia points to needs in mental health services; a better way to reduce hospital readmissions

Research report focuses on the impact of real-time cost information within a primary care

First molecular test developed to detect eosinophilic esophagitis

Scientists hope to find new treatments for traumatic brain injury

New NIH grant to help Chicago Stroke Trials Consortium accelerate treatment for stroke

Air quality forecast play an increasing role in mitigating health risk

CKD children with lower socio-economic status less likely to grow to normal height ranges

High knowledge about HIV and risky sexual activity does not make teens more likely to get tested for HIV

Communicating with partners about parenting and HIV helps young people

Study shows relative increase of 322% for severe pre-eclampsia

New tool provides first comprehensive guide to optimize ostomy management

QoL, BMI predict exacerbations in Japanese COPD patients

Conversion from psychotic depression to bipolar disorder explored

Keeping active reduces women’s Crohn’s risk

Antibiotic resistance holds stable in U.S. children's hospitals

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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