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Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

What we are trying to do is take a cancer model like the PDX model (patient-derived tumor xenograft), which is a human-derived cancer growing in an in vivo model and apply radiation to that model.

From Xstrahl 20 Nov 2013

First Edition: November 20, 2013

Today's early morning highlights from the major news organizations, including reports that President Barack Obama places some of the blame for the health law's woes with Republicans, and details of comments by an Obama administration tech official that a large portion of the healthcare.gov 'back office' functions are yet to be built.

20 Nov 2013

Staphylococcus Aureus Bacteria anticipates and turns immune defenses against the host

Around 20 percent of all humans are persistently colonized with Staphylococcus aureus bacteria, a leading cause of skin infections and one of the major sources of hospital-acquired infections, including the antibiotic-resistant strain MRSA.

20 Nov 2013

Rapid DNA biochip tests for screening disease-causing bacteria

Patients affected by a bacterial infection can usually be treated with an antibiotic. But sometimes a resistant bacterial strain is causing the infection. In a hospital setting, doctors ideally want to know if they are dealing with such bacteria and which drugs they should choose. But if the doctor runs a test it can take days to get a result. Now, a European project is paving the way for much more rapid tests using DNA biochips. The aim is to rapidly screen disease-causing bacteria using a microarray to spot which resistant genes are present in bacteria.

20 Nov 2013

NeutroPhase irrigation therapy and NPWT help treat severe flesh eating and wound infections

NovaBay Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company developing topical non-antibiotic antimicrobial products, today announced the publication of a scientific paper by Dr. John R. Crew of Seton Medical Center, Daly City, California, describing the first use of adjunctive NeutroPhase irrigation therapy in conjunction with Negative Pressure Wound Therapy to successfully manage the severely-infected wound in the arm of a patient with life-threatening 'flesh-eating' disease.

20 Nov 2013

Metal coil therapy may provide same benefits as major surgery for COPD

Brown was diagnosed with COPD and emphysema, the third leading cause of death in the United States, only behind heart disease and cancer. Right now, the only studied interventions that prolong life for patients with severe COPD are supplemental oxygen in people with low oxygen levels and lung volume reduction surgery (LVRS) in appropriately selected individuals. Like most COPD patients, Brown was given medication but told there was no cure. He was 58 years old.

20 Nov 2013

Enhancing the NMDA glutamate receptor causes antidepressant-like effects

Thirteen years ago, an article in this journal first reported that the anesthetic medication, ketamine, showed evidence of producing rapid antidepressant effects in depressed patients who had not responded to prior treatments. Ketamine works by blocking one of the targets for the neurotransmitter glutamate in the brain, the N-methyl-D-aspartate (NMDA) glutamate receptor.

20 Nov 2013

Linde Healthcare introduces intelligent digital oxygen cylinders with integrated pressure regulators

The new generation of oxygen cylinders, with an integrated pressure regulator that calculates and shows remaining time to the exact minute. LIV IQ is also equipped with various visible and audible alerts which enhance patient safety in mobile oxygen therapy. All together, these features free up time for healthcare professionals to concentrate on the patient and enable a cost-effective use of cylinder content.

20 Nov 2013

State highlights: Calif. fines three insurers for denying therapy; Colo.'s Denver Health to shed jobs; Ambulance Co. agrees to pay feds $3M over fraud allegations

California officials said three of the state's largest health insurers illegally denied speech and occupational therapy to patients, and regulators fined one of the companies, Health Net Inc., $300,000 for repeated violations. The state Department of Managed Health Care said Monday that it ordered Health Net, Anthem Blue Cross and Blue Shield of California to stop denying medically necessary therapy in cases of developmental disabilities, autism and other medical conditions.

20 Nov 2013

Higher 36°C temperature as effective as 33°C for therapeutic hypothermia treatment

Therapeutic hypothermia - cooling the body and brain down to 33-C - is the method used worldwide to treat cardiac arrest, even though a lower body temperature may raise the risk of side-effects. However, keeping the temperature steady at 36-C is just as effective, a study led by Lund University researchers has found.

20 Nov 2013

Connectivity, size of brain can predict degree of anxiety in young children

Prolonged stress and anxiety during childhood is a risk factor for developing anxiety disorders and depression later in life. Now, Stanford University School of Medicine researchers have shown that by measuring the size and connectivity of a part of the brain associated with processing emotion - the amygdala - they can predict the degree of anxiety a young child is experiencing in daily life.

20 Nov 2013

Study on injuries to the ureter during robotic prostatectomy

There may be warning signs to help surgeons avoid damaging part of the urinary system during robot-assisted surgical removal of prostate cancer, ultimately preventing the expense of additional surgery, according to researchers at Henry Ford's Vattikuti Urology Institute.

20 Nov 2013

Study shows cognitively impaired older adults released from hospital less likely to be rehospitalized

Cognitively impaired older adults released from the hospital are less likely to be rehospitalized within 30 days if they go to a nursing home than if they return to their own home or the home of a family member, according to an Indiana University and Regenstrief Institute study.

20 Nov 2013

Senate gives final approval to bill tightening control over drug-compounding pharmacies

The Senate gave final approval to a bill Monday that gives federal regulators greater oversight of compounding pharmacies like the ones responsible for a deadly meningitis outbreak last year. The President is expected to sign the bill.

20 Nov 2013

Mount Sinai researchers win Best Manuscript Award for research on repair, reversal of heart attack damage

The Editors of the American Heart Association's (AHA) journal Circulation Research have awarded Icahn School of Medicine at Mount Sinai researchers a "Best Manuscript Award" for their investigations on repair and reversal of heart attack damage.

20 Nov 2013

Simple blood test may predict people at highest risk for developing heart problems

For years, doctors have been divided on how effective annual testing and screenings are for apparently healthy individuals. New research, however, shows that a simple blood test may predict who is at highest risk to develop heart problems - and how long these people may have to live.

20 Nov 2013

Findings could potentially save millions of people from having unnecessary cardiac catheterization

An ultrafast, 320-detector computed tomography scanner that shows both anatomy within coronary arteries and blood flow can accurately sort out which people need - or don't need - an invasive procedure to identify coronary blockages, according to an international study. The researchers say their findings could potentially save millions of people worldwide from having an unnecessary cardiac catheterization.

20 Nov 2013

Study finds patients with focal epilepsy have widespread, abnormal connections in their brains

Patients with the most common form of focal epilepsy have widespread, abnormal connections in their brains that could provide clues toward diagnosis and treatment, according to a new study published online in the journal Radiology.

20 Nov 2013

Research provides first rigorous comparison of 2 surgical approaches for severe heart valve disease

New research presented today at the 2013 Scientific Sessions of the American Heart Association by researchers at the Perelman School of Medicine at the University of Pennsylvaniafound no difference in outcomes at one-year between two recommended surgical options for treating ischemic mitral regurgitation (IMR) - repair of the leaky valve or its replacement with an artificial valve.

20 Nov 2013

Youth prefer rapid point-of-care HIV tests than traditional blood tests

Youth prefer, accept and receive HIV results more often when offered rapid finger prick or saliva swab tests rather than traditional blood tests according to a study by researchers at St. Michael's Hospital.

20 Nov 2013

Hospital News and Research

Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

First Edition: November 20, 2013

Staphylococcus Aureus Bacteria anticipates and turns immune defenses against the host

Rapid DNA biochip tests for screening disease-causing bacteria

NeutroPhase irrigation therapy and NPWT help treat severe flesh eating and wound infections

Metal coil therapy may provide same benefits as major surgery for COPD

Enhancing the NMDA glutamate receptor causes antidepressant-like effects

Linde Healthcare introduces intelligent digital oxygen cylinders with integrated pressure regulators

State highlights: Calif. fines three insurers for denying therapy; Colo.'s Denver Health to shed jobs; Ambulance Co. agrees to pay feds $3M over fraud allegations

Higher 36°C temperature as effective as 33°C for therapeutic hypothermia treatment

Connectivity, size of brain can predict degree of anxiety in young children

Study on injuries to the ureter during robotic prostatectomy

Study shows cognitively impaired older adults released from hospital less likely to be rehospitalized

Senate gives final approval to bill tightening control over drug-compounding pharmacies

Mount Sinai researchers win Best Manuscript Award for research on repair, reversal of heart attack damage

Simple blood test may predict people at highest risk for developing heart problems

Findings could potentially save millions of people from having unnecessary cardiac catheterization

Study finds patients with focal epilepsy have widespread, abnormal connections in their brains

Research provides first rigorous comparison of 2 surgical approaches for severe heart valve disease

Youth prefer rapid point-of-care HIV tests than traditional blood tests

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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