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Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

In a recent study posted to the bioRxiv* server, researchers at the United States Army Medical Research Institute of Infectious Diseases evaluated the immunogenicity of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) deoxyribonucleic acid (DNA) vaccine, nCOV-S(JET), in rhesus macaques

18 Sep 2022

Research examines the roles of cytokines during SARS-CoV-2 infection in rhesus macaques

In a recent study posted to the bioRxiv* preprint server, researchers in the United States assessed the role of two cytokines, interferon-gamma (IFN-γ) and interleukin-10 (IL-10), in regulating immune cell responses and inflammation early during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in rhesus macaques.

18 Sep 2022

Researchers identify universal features shaping organelle gene retention

Mitochondria are compartments – so-called "organelles" -- in our cells that provide the chemical energy supply we need to move, think, and live.

16 Sep 2022

UCLA announces participation in a phase 3 trial evaluating tecovirimat for the treatment of monkeypox

The UCLA Clinical AIDS Research and Education (CARE) Center today announced its participation in STOMP (Study of Tecovirimat for Human Monkeypox Virus), or A5418, a phase 3, randomized, placebo-controlled, double-blind trial evaluating the safety and efficacy of tecovirimat for the treatment of human monkeypox.

16 Sep 2022

Study explores the long-term impact of telemedicine on child neurology care

Researchers from the Epilepsy Neurogenetics Initiative (ENGIN) at Children's Hospital of Philadelphia (CHOP) found that across nearly 50,000 visits, patients continued to use telemedicine effectively even with the reopening of outpatient clinics a year after the onset of the COVID-19 pandemic.

16 Sep 2022

BU researcher urges the U.S. to create a National Long COVID Compensation Program

While the COVID-19 pandemic wanes, the U.S. continues to face a national health challenge – the effective and equitable care of individuals with Long COVID.

16 Sep 2022

Balanced meal timing has potentially positive effects on cognitive health

Globally, there are approximately 55 million people who suffer from dementia, and the incidence of the disease has steadily increased.

16 Sep 2022

Single-cell RNA sequencing reveals dynamic immune landscape during the early stages of bubonic plague

This study is led by Dr. Ruifu Yang, Dr. Zongmin Du (State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology) and Dr. Fan Bai (Biomedical Pioneering Innovation Center, School of Life Sciences, Peking University).

16 Sep 2022

UOC-led project aims to improve public spaces in cities to benefit neurodivergent children

A project led by the Universitat Oberta de Catalunya and involving Barcelona City Council, the Global Institute of Neurodevelopment Integrated Care and LEMUR urban emergency laboratory aims to improve public spaces in cities to benefit neurodivergent children – minority groups of children with neurological differences, and children with autism spectrum disorder (ASD) in particular.

16 Sep 2022

Study may lead to a new way for treating children with eosinophilic esophagitis

A groundbreaking study from Ann & Robert H. Lurie Children's Hospital of Chicago determined the threshold for a new measure of early scarring in the esophagus of children with eosinophilic esophagitis (EoE), which allows immediate intervention during endoscopy to halt further damage and prevent food from getting stuck in the esophagus (feeding tube) of kids with this condition.

16 Sep 2022

Study supports the importance of healthy diet for better cognitive function across races, ethnicities

Dietary choices and their consequences may certainly influence cognitive function. A new study led by investigators at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, along with outside collaborators expands on previously published work (focused on Puerto Rican individuals in the U.S.) by including additional races and ethnicities.

16 Sep 2022

Study investigates the link between protein intake and skeletal muscle mass in kidney transplant recipients

Conventional wisdom holds that low protein intake is essential for kidney disease patients. However, scientists from Osaka Metropolitan University demonstrated that it might not always be the case with their recent study on the relationship between protein intake and skeletal muscle mass in kidney transplant recipients.

16 Sep 2022

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

If a secretion in the lungs’ alveoli is not cleared regularly, breathing difficulties can develop. In a study published in Science Immunology, a team led by Alexander Mildner and Achim Leutz has now explained the pivotal role of the transcription factor C/EBPb in this process.

16 Sep 2022

Lab experiments add further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19's viral pathogenesis - a theory that was posited two years ago by a team of researchers at the Department of Energy's Oak Ridge National Laboratory.

16 Sep 2022

Research News and Research

Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

Research examines the roles of cytokines during SARS-CoV-2 infection in rhesus macaques

Researchers identify universal features shaping organelle gene retention

UCLA announces participation in a phase 3 trial evaluating tecovirimat for the treatment of monkeypox

Study explores the long-term impact of telemedicine on child neurology care

BU researcher urges the U.S. to create a National Long COVID Compensation Program

Balanced meal timing has potentially positive effects on cognitive health

Single-cell RNA sequencing reveals dynamic immune landscape during the early stages of bubonic plague

UOC-led project aims to improve public spaces in cities to benefit neurodivergent children

Study may lead to a new way for treating children with eosinophilic esophagitis

Study supports the importance of healthy diet for better cognitive function across races, ethnicities

Study investigates the link between protein intake and skeletal muscle mass in kidney transplant recipients

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

Lab experiments add further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis

Study identifies a promising target for polycystic kidney disease treatment

UW Medicine researchers seek participants for Phase 3 clinical trial of a drug to treat monkeypox

Azerbaijan Thalassemia Center and BGI partner to improve thalassemia screening in Azerbaijan

Experts recommend nuanced messaging and accurate communication on zoonotic spillover risk

Antibody drugs are not recommended for patients with covid-19, say WHO experts

Research may open the way to developing treatments for rare movement disorders

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