Research News and Research

RSS

Blocking FNDC5 prevents cancer-induced cachexia in mice

The severe muscle atrophy and weakness commonly associated with cancer growth (i.e., cachexia) can be prevented simply by being deprived of FNDC5, the precursor of the exercise hormone irisin, researchers from the Indiana University School of Medicine have found.

12 Sep 2022

Vaccines that induce mucosal immunity against SARS-CoV-2 are needed

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom studied assessed plasma and nasal antibody (Ab) responses induced after a year of coronavirus disease 2019 (COVID-19)-associated hospitalization and the potential boost by subsequent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccinations in the United Kingdom (UK).

12 Sep 2022

Study reveals recommended levels of long-term blood sugar to avoid diabetes-related damage

The levels of long-term blood sugar, HbA1c, can be used to accurately determine the risk of a person with type 1 diabetes developing eye- and kidney complications.

12 Sep 2022

Oral anticoagulant drug may be safe, effective in preventing blood clots after urologic cancer surgery

The oral anticoagulant drug apixaban may offer a safer, more effective alternative to standard home heparin injections for patients taking extended prophylaxis (EP) to prevent blood-clot-related complications after surgery, reports a study in The Journal of Urology, an Official Journal of the American Urological Association.

12 Sep 2022

Neoadjuvant NHAs followed by surgery can improve key outcomes in high-risk prostate cancer patients

For high-risk patients with prostate cancer, treatment with novel hormonal agents (NHAs) followed by surgery can reduce the risk of recurrent and progressive cancer, compared to initial treatment with surgery, suggests a study in The Journal of Urology®, an Official Journal of the American Urological Association (AUA).

12 Sep 2022

Are pesticides affecting childhood growth in low-income countries?

Researchers assess the risk posed by these chemicals to the developing fetus and child.

12 Sep 2022

Researchers uncover the structure of protein fibrils linked to hereditary form of human prion disease

In a new study, researchers from the Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease.

12 Sep 2022

Extreme heat events may increase risk of hypo- and hyperglycemia–related emergencies

The global effects of climate change have been demonstrated to extend beyond the environment to many other areas including human health, particularly with respect to different health conditions.

12 Sep 2022

Long-COVID in adults and Ontario's expected burden

Scientists identify the healthcare requirements for adults with long COVID.

12 Sep 2022

Meal timing may influence mood vulnerability in night workers

Beating the blues with food? A new study adds evidence that meal timing may affect mental health, including levels of depression- and anxiety-related mood.

12 Sep 2022

Regular patterns of activity are important for healthy aging and mental health, study suggests

Older adults who consistently get up early and remain active throughout the day are happier and perform better on cognitive tests than those with irregular activity patterns, according to a new study led by University of Pittsburgh researchers.

12 Sep 2022

Neuroscientists reveal precise connections between retinal nerve cells and the midbrain structure

For the first time, neuroscientists from Charité – Universitätsmedizin Berlin and the Max Planck Institute for Biological Intelligence (currently in the process of being established) have revealed the precise connections between sensory neurons inside the retina and the superior colliculus, a structure in the midbrain.

12 Sep 2022

Phase I/II LIBRETTO-001 trial: RET inhibitor achieves durable objective responses across multiple tumors

The highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses across multiple tumor types in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of Texas MD Anderson Cancer Center.

12 Sep 2022

New cold perfusion approach to isolate hepatic stellate cells from fatty liver-associated tumors

Obesity can give rise to a variety of health concerns. Nonalcoholic steatohepatitis (NASH) - a type of fatty liver disease that might progress to cancer - is particularly prevalent among obese people.

12 Sep 2022

Study underscores the economic, mental health impacts of COVID-19 on people hit by climate disasters

When the Children's Environmental Health Initiative (CEHI) launched the Texas Flood Registry in April 2018, the goal was to develop a needs assessment focusing on health and housing impacts of the greater Houston area, which was still recovering less than one year after Hurricane Harvey's devastating landfall.

12 Sep 2022

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Newly released results from the Phase III ADAURA trial reveal that osimertinib yielded a 5.5-year median disease-free survival in the post-surgical treatment of patients with EGFR-mutated lung cancer, and nearly three in four patients treated with adjuvant osimertinib were disease-free at four years.

12 Sep 2022

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Significant improvement in progression-free survival and response rate combined with reduced symptoms and better quality of life are reported as outcomes of a new treatment approach for patients with desmoid tumors, which are benign, but locally aggressive and invasive soft tissue tumors.

12 Sep 2022

Scientists estimate the impact of genetic risk factors on the loss of healthy life years

Researchers have, for the first time, systematically estimated the impact of a range of different disease-associated genetic risk factors on the loss of healthy life years. Knowing the contribution of different genetic risk factors on disease burden can help prioritise and design interventions using genetic information.

12 Sep 2022

Study identifies new therapeutic target against lung adenocarcinoma

The TIMP-1 protein levels in both tissues and blood have been repeatedly associated with a poor prognosis in lung cancers, but its role in this cancer process was, to date, unknown.

12 Sep 2022

Caregivers in nursing homes experienced high stress levels during the pandemic, study reveals

Caregivers are particularly important during a public health crisis. Now, researchers from Japan have found that caregivers working in nursing homes experienced high levels of psychological distress during the COVID-19 pandemic.

12 Sep 2022

Research News and Research

Blocking FNDC5 prevents cancer-induced cachexia in mice

Vaccines that induce mucosal immunity against SARS-CoV-2 are needed

Study reveals recommended levels of long-term blood sugar to avoid diabetes-related damage

Oral anticoagulant drug may be safe, effective in preventing blood clots after urologic cancer surgery

Neoadjuvant NHAs followed by surgery can improve key outcomes in high-risk prostate cancer patients

Are pesticides affecting childhood growth in low-income countries?

Researchers uncover the structure of protein fibrils linked to hereditary form of human prion disease

Extreme heat events may increase risk of hypo- and hyperglycemia–related emergencies

Long-COVID in adults and Ontario's expected burden

Meal timing may influence mood vulnerability in night workers

Regular patterns of activity are important for healthy aging and mental health, study suggests

Neuroscientists reveal precise connections between retinal nerve cells and the midbrain structure

Phase I/II LIBRETTO-001 trial: RET inhibitor achieves durable objective responses across multiple tumors

New cold perfusion approach to isolate hepatic stellate cells from fatty liver-associated tumors

Study underscores the economic, mental health impacts of COVID-19 on people hit by climate disasters

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Scientists estimate the impact of genetic risk factors on the loss of healthy life years

Study identifies new therapeutic target against lung adenocarcinoma

Caregivers in nursing homes experienced high stress levels during the pandemic, study reveals

A guide to advancing biotherapeutic research eBook

Latest eBooks

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence