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Researchers identify gene that orchestrates important branching of nerve fibers

Our ability to detect heat, touch, tickling and other sensations depends on our sensory nerves. Now, for the first time, researchers at Albert Einstein College of Medicine of Yeshiva University have identified a gene that orchestrates the crucially important branching of nerve fibers that occurs during development. The findings were published online today in the journal Cell.

11 Oct 2013

Suppression of mitochondria: A dominant feature of diabetic kidney disease

Researchers at the University of California, San Diego School of Medicine have identified 13 metabolites - small molecules produced by cellular metabolism - that are significantly different in patients with diabetes and chronic kidney disease compared to healthy controls.

11 Oct 2013

Rutgers Eric B. Chandler Health Center gets Level 2 Patient-Centered Medical Home recognition

For individuals with limited resources, "health care" may consist of a series of unrelated visits to different doctors, clinics, even emergency departments—siloed, episodic care when needed. Rutgers Eric B. Chandler Health Center, a comprehensive, family-oriented community health center, has been working hard to change that experience.

11 Oct 2013

Involving patients, families in healthcare system enhances safety and quality outcomes

Individual patient outcomes and overall community health can be enhanced and improved when medical providers partner with patients and families in the design and delivery of health care services, according to a leading patient advocate in her keynote address at the National Association for Healthcare Quality annual educational conference.

11 Oct 2013

US health care spending to grow at an average annual rate of 5.8% for 2012-22

New estimates released 9/18/13 from the Office of the Actuary at the Centers for Medicare and Medicaid Services project that aggregate health care spending in the United States will grow at an average annual rate of 5.8 percent for 2012-22, or 1.0 percentage point faster than the expected growth in the gross domestic product.

11 Oct 2013

Reducing risk factors like hypertension might lower risk of heart disease for childhood survivors

For childhood cancer survivors, risk factors associated with lifestyle, particularly hypertension, dramatically increase the likelihood of developing serious heart problems as adults, according to a national study led by St. Jude Children's Research Hospital. The findings appear in the current issue of the Journal of Clinical Oncology.

11 Oct 2013

Depression in Parkinson's disease people associated with reduced dopamine synthesis capacity

According to the Parkinson's Disease Foundation, up to 60% of individuals with Parkinson's disease exhibit mild to moderate depression, which is often underdiagnosed. It is unclear whether depression results from having a debilitating disease or reflects a parallel abnormal change in the brain caused by PD pathophysiology.

11 Oct 2013

Cleveland healthcare institutions receive $1M grant to develop Stroke Clinical Trials Coordinating Center

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11 Oct 2013

Children who stutter have less grey matter in brain regions responsible for speech production

A new study by a University of Alberta researcher shows that children who stutter have less grey matter in key regions of the brain responsible for speech production than children who do not stutter.

11 Oct 2013

Palliative chemoradiation boosts survival, QoL in poor-prognosis NSCLC

C hemoradiation is superior to chemotherapy alone with respect to both survival and quality of life in patients with inoperable non-small-cell lung cancer, a phase III trial has found.

10 Oct 2013

Constellation Pharmaceuticals awarded grant to facilitate study of epigenetic control of inflammation

Constellation Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company in the field of epigenetics, today announced that it has been awarded a research grant in collaboration with the University of Pittsburgh School of Medicine from the Cystic Fibrosis Foundation to explore the potential use of BET bromodomain inhibitors for the control of inflammation in cystic fibrosis.

10 Oct 2013

FDA clears Sotera Wireless' patented continuous non-invasive blood pressure technology

Sotera Wireless, Inc. today announced the U.S. Food and Drug Administration has cleared the Company's patented continuous non-invasive blood pressure technology, a new feature of the ViSi Mobile wireless patient monitoring system. For the first time clinicians can continuously monitor all patient vital signs, including beat-to-beat blood pressure, without the use of a catheter or blood pressure cuff.

10 Oct 2013

First Edition: October 10, 2013

Today's headlines include a new Associated Press poll that offers the public's early reviews of the first days of the health law's online insurance marketplaces.

10 Oct 2013

Drugs often fail to bring acromegaly under control in routine clinical practice

Over a quarter of UK patients treated for growth hormone-producing tumours do not achieve 'safe' growth hormone levels, according to a 30 year UK multi-centre study of clinical management of the rare disease acromegaly. The findings by the Society for Endocrinology UK Acromegaly Register, published in the November issue of Clinical Endocrinology, show that drugs to control acromegaly often fail to bring the disease completely under control in routine clinical practice.

10 Oct 2013

Combining gene therapy with stem cells leads to faster healing of burns

Johns Hopkins researchers, working with elderly mice, have determined that combining gene therapy with an extra boost of the same stem cells the body already uses to repair itself leads to faster healing of burns and greater blood flow to the site of the wound.

10 Oct 2013

Patients who received care at multiple HIV clinics have higher HIV viral loads

Patients who received care at multiple HIV clinics—as opposed to only one— were less likely to take their medication and had higher HIV viral loads, a new study published in the journal AIDS and Behavior of almost 13,000 HIV patients in Philadelphia from Penn Medicine found.

10 Oct 2013

Bluhm Institute enrolls first patient in SALUS trial to evaluate movable, non-metallic heart valve

Northwestern's Bluhm Cardiovascular Institute has enrolled its first participant in SALUS, a clinical trial studying the effectiveness of a prosthetic aortic heart valve that can be placed without open-heart surgery.

10 Oct 2013

Charles J. Sherr to receive Prize for Scientific Excellence in Medicine

Charles J. Sherr, M.D., Ph.D., chair of the St. Jude Children's Research Hospital Department of Tumor Cell Biology and a Howard Hughes Medical Institute Investigator, has been selected to receive the 2013 Prize for Scientific Excellence in Medicine by the American-Italian Cancer Foundation.

10 Oct 2013

Intravenous feeding can cause liver damage, say researchers

Researchers know that feeding some patients intravenously can save their lives - but also can cause liver damage. Now scientists at the University of Colorado and Children's Hospital Colorado have figured out the likely culprit, one of the ingredients in intravenous food, behind the liver problems.

10 Oct 2013

BMC finds patients with high degree of skills, confidence less likely to have hospital readmissions

A study by physicians at Boston Medical Center (BMC), has found that patients with a high degree of activation (possessing the knowledge, skills, confidence and inclination to assume responsibility for managing one's health and health-care needs) were less likely to be readmitted to the hospital within 30 days of discharge than those with a low level of activation.

10 Oct 2013

Hospital News and Research

Researchers identify gene that orchestrates important branching of nerve fibers

Suppression of mitochondria: A dominant feature of diabetic kidney disease

Rutgers Eric B. Chandler Health Center gets Level 2 Patient-Centered Medical Home recognition

Involving patients, families in healthcare system enhances safety and quality outcomes

US health care spending to grow at an average annual rate of 5.8% for 2012-22

Reducing risk factors like hypertension might lower risk of heart disease for childhood survivors

Depression in Parkinson's disease people associated with reduced dopamine synthesis capacity

Cleveland healthcare institutions receive $1M grant to develop Stroke Clinical Trials Coordinating Center

Children who stutter have less grey matter in brain regions responsible for speech production

Palliative chemoradiation boosts survival, QoL in poor-prognosis NSCLC

Constellation Pharmaceuticals awarded grant to facilitate study of epigenetic control of inflammation

FDA clears Sotera Wireless' patented continuous non-invasive blood pressure technology

First Edition: October 10, 2013

Drugs often fail to bring acromegaly under control in routine clinical practice

Combining gene therapy with stem cells leads to faster healing of burns

Patients who received care at multiple HIV clinics have higher HIV viral loads

Bluhm Institute enrolls first patient in SALUS trial to evaluate movable, non-metallic heart valve

Charles J. Sherr to receive Prize for Scientific Excellence in Medicine

Intravenous feeding can cause liver damage, say researchers

BMC finds patients with high degree of skills, confidence less likely to have hospital readmissions

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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