Immune Response News and Research

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Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

A study conducted at the University of Campinas in the state of São Paulo, Brazil, shows that compounds produced by gut microbiota (bacteria and other microorganisms) during fermentation of insoluble fiber from dietary plant matter do not affect the ability of the novel coronavirus SARS-CoV-2 to enter and replicate in cells lining the intestines.

30 Mar 2021

Single dose of Pfizer and Oxford vaccines shows 60% efficacy in elderly care home residents

A new study deals with the effect of two widely used vaccines in eliciting humoral immunity against the virus in this group. These are the Oxford/AstraZeneca viral-vectored vaccine (ChAdOx1 nCoV-19), and the Pfizer/BioNTech’s messenger RNA-based vaccine (BNT162b2). Both express the viral spike antigen, and both are currently being employed in the UK’s vaccination program.

30 Mar 2021

Study finds rapid increase in IgG and IgA antibody levels following COVID-19 mRNA vaccination

A new study describes the kinetics of the antibody response to the earliest approved vaccines against COVID-19, which were developed on an mRNA platform.

30 Mar 2021

Researchers develop broadly neutralizing SARS-CoV-2 ferritin nanoparticle vaccine

In the continued need for next-generation vaccines that confer broad protection against COVID-19, scientists developed an adjuvanted SARS-CoV-2 Spike Ferritin Nanoparticle (SpFN) vaccine.

30 Mar 2021

Determination of vaccine-elicited SARS-CoV-2 antibodies in breastmilk

A new study has analyzed the levels of SARS-CoV-2 antibodies elicited by the novel COVID-19 vaccines in breastmilk.

30 Mar 2021

New study reports increased spread of B.1.1.7 variant in Houston, Texas

Research led by Jimmy Gollihar from the CCDC Army Research Laboratory-South in Austin, Texas found the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant B.1.1.7 —first detected last fall in England — increased in Houston, Texas. The B.1.1.7 variant is rapidly spreading with a case doubling time of 6.9 days.

29 Mar 2021

Apes mount a much stronger early immune response compared to African and Asian monkeys

A new study out of the University of Chicago and the University of Illinois Urbana-Champaign in humans, chimpanzees, rhesus macaques and baboons has found key differences in early gene expression in response to pathogen exposure, highlighting the importance of choosing the right animal model for the right questions.

29 Mar 2021

Rare genetic variant may explain severe COVID-19 in young healthy male patients

A recent study describes the association of rare alleles in a specific gene with severe COVID-19 in young male patients.

29 Mar 2021

Researchers develop novel nanoadjuvant COVID-19 vaccine candidate

Researchers at the National Center for Nanoscience and Technology of China, the Chinese Academy of Sciences (CAS), introduced a new vaccine, which compromises the spike protein’s receptor-binding domain (RBD) and the manganese nanoadjuvant (MnARK), inducing humoral and cellular responses.

29 Mar 2021

In his continued sparring with Fauci, Sen. Rand Paul oversimplified the science

That Sen. Rand Paul of Kentucky often disagrees with infectious-disease expert Dr. Anthony Fauci is well known.

29 Mar 2021

Large U.S. study identifies sociodemographic and clinical factors associated with SARS-CoV-2 testing and positivity

The massive and continuing outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), throughout the world, has led to a staggering toll of over 549,000 deaths in the USA, among over 30 million cases. A new preprint research paper posted to the medRxiv* server discusses the factors related to the chances of testing positive for this virus.

29 Mar 2021

Persistent impact on smell and taste in COVID-19 patients one year later

The presentation of the infection ranges from asymptomatic, through dry cough with fever, anosmia/dysgeusia, to shortness of breath with severe acute respiratory distress syndrome (ARDS). A new preprint research paper posted to the medRxiv* server reports on the clinical progression of anosmia and dysgeusia, in particular, one year after the infection.

29 Mar 2021

Single Sputnik V vaccine dose elicits robust immune response in previously infected individuals

A new preprint research paper posted to the medRxiv server describes successful immunization of the vaccinated population with a single dose of the Russian-made Sputnik V vaccine.

29 Mar 2021

Linear epitope mapping of the SARS-CoV-2 spike protein

The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been the primary target of many drug discovery efforts and is similarly utilized in each of the approved COVID-19 vaccines to elicit the generation of anti-spike protein antibodies, thereby granting immunity.

28 Mar 2021

New project receives $9 million CIHR funding to track global threat of COVID-19 variants

A project spearheaded by a researcher at the University of Ottawa's Faculty of Medicine has been awarded $9 million in Canadian Institutes of Health Research (CIHR) funding to create a national network for better researching and responding to the global threat COVID-19 variants pose.

26 Mar 2021

A novel approach to oral vaccination against Covid-19

Scientists at the University of Würzburg together with a pharmaceutical company are working on a novel approach to oral vaccination against the coronavirus.

26 Mar 2021

Longitudinal study of SARS-CoV-2 antibodies following vaccination

A longitudinal study of IgG antibody levels in vaccinated healthcare workers was recently uploaded to the preprint server medRxiv*, suggesting that IgG levels could be a reliable indicator of successful vaccination.

26 Mar 2021

One dose of Pfizer vaccine generates strong immune response against COVID-19

A new study led by the Universities of Sheffield and Oxford with support from the UK Coronavirus Immunology Consortium (UK-CIC) has found that 99 per cent of people generate a robust immune response against Covid-19 after just one dose of the Pfizer vaccine.

26 Mar 2021

DAPK3 slows tumor growth by activating fierce-sounding STING pathway

The glow of a panther's eyes in the darkness. The zig-zagging of a shark's dorsal fin above the water. Humans are always scanning the world for threats.

26 Mar 2021

Newly identified pathway controls dangerous overreactions in the body's immune system

Scientists at Sinai Health say they have discovered a new pathway that controls dangerous overreactions in a body's immune system, including deadly forms of hyper-inflammation.

26 Mar 2021

Immune Response News and Research

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

Single dose of Pfizer and Oxford vaccines shows 60% efficacy in elderly care home residents

Study finds rapid increase in IgG and IgA antibody levels following COVID-19 mRNA vaccination

Researchers develop broadly neutralizing SARS-CoV-2 ferritin nanoparticle vaccine

Determination of vaccine-elicited SARS-CoV-2 antibodies in breastmilk

New study reports increased spread of B.1.1.7 variant in Houston, Texas

Apes mount a much stronger early immune response compared to African and Asian monkeys

Rare genetic variant may explain severe COVID-19 in young healthy male patients

Researchers develop novel nanoadjuvant COVID-19 vaccine candidate

In his continued sparring with Fauci, Sen. Rand Paul oversimplified the science

Large U.S. study identifies sociodemographic and clinical factors associated with SARS-CoV-2 testing and positivity

Persistent impact on smell and taste in COVID-19 patients one year later

Single Sputnik V vaccine dose elicits robust immune response in previously infected individuals

Linear epitope mapping of the SARS-CoV-2 spike protein

New project receives $9 million CIHR funding to track global threat of COVID-19 variants

A novel approach to oral vaccination against Covid-19

Longitudinal study of SARS-CoV-2 antibodies following vaccination

One dose of Pfizer vaccine generates strong immune response against COVID-19

DAPK3 slows tumor growth by activating fierce-sounding STING pathway

Newly identified pathway controls dangerous overreactions in the body's immune system

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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