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New nuclear medicine approach shows potential for precision treatment of solid tumors

A novel nuclear medicine approach is showing great promise for precision treatment of solid tumors in many types of cancer--including lung, breast, pancreas and ovarian in adults and glioma, neuroblastoma and sarcoma in children.

26 Jun 2018

Novel theranostic agent designed for precise tumor diagnosis and therapy

A novel, intelligent theranostic agent for precise tumor diagnosis and therapy has been developed that remains as small molecules while circulating in the bloodstream, can then self-assemble into larger nanostructures in the tumor, and be activated by the tumor microenvironment for therapy guided by photoacoustic imaging.

26 Jun 2018

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Pancreatic cancer is lethal in about 95% of cases mostly due to failure of first-line therapy gemcitabine. AntiCancer Inc.'s oral methioninase (AC 00619), which is in late pre-clinical development as an anti-cancer as well as an anti-aging drug, has now been shown to overcome gemcitabine resistance in mouse models of human pancreatic cancer, including AntiCancer's patient-derived orthotopic xenograft mouse models.

25 Jun 2018

Studying The Effects of Microgravity on Muscle Mass

Studying the effects of gravity on muscle cells can give us an insight into muscle wastage diseases, and potentially guide the development of new therapies. Professor Louis Yuge discusses his research and the cellular changes that occur in response to microgravity.

25 Jun 2018

Researchers discover drug compound that inhibits movement of cancer cells

Fighting cancer means killing cancer cells. However, oncologists know that it's also important to halt the movement of cancer cells before they spread throughout the body.

22 Jun 2018

Researchers develop new guide for using mechanical stimulation to enhance tissue-engineered cartilage

Tissue-engineered articular cartilage for repairing cartilage damaged by trauma or disease can be made to more closely mimic natural AC if mechanical stimulation of particular magnitude and duration is applied during the development process.

22 Jun 2018

Researchers create revolutionary model to study pulmonary diseases

Researchers at the University of Arizona College of Medicine - Phoenix have developed a revolutionary "lung on a leaf" to study pulmonary diseases.

21 Jun 2018

Multidisciplinary Human-Focused Research

The work that we're doing in particular involves the development of better models of the human body. To do that, we need to put together cells, tissues, culture them in an artificial environment so that they feel as if they're inside the human body.

From Logos Biosystems 20 Jun 2018

Quick adoption of new diagnostic tests could help NHS to save nearly £7 billion

Research commissioned by Innovate UK and the British In Vitro Diagnostics Association reveals that the NHS could save over £6.9 billion in five years through quick adoption of new diagnostic tests as they come onto the market. In turn, these savings could help tackle the annual NHS shortfall, widely expected to reach £20 billion by 2022.

20 Jun 2018

Researchers invent medical device for proliferation, differentiation of neural stem cells

The research team of Hong Kong Baptist University invented a medical device with a specific nanotechnology layer for the proliferation and differentiation of neural stem cells in vitro.

20 Jun 2018

Study: Effects of in vitro fertilization depend on genetic variation inherited from parents

In vitro fertilization affects the regulatory region of genes essential for placental and embryonic growth, as well as the birth weight.

19 Jun 2018

Researchers develop new method to preserve fertility in boys with prepubertal cancer

Ben-Gurion University of the Negev and Soroka University Medical Center researchers in Beer-Sheva, Israel are developing a cell culture system that for the first time can change testicular stem cells into sperm-like cells that may enable future fertility for boys with prepubertal cancer.

18 Jun 2018

Study combines gene editing and stem cell technologies to predict person’s risk for heart disease

Scientists may now be able to predict whether carrying a specific genetic variant increases a person's risk for disease using gene editing and stem cell technologies, according to new research in the American Heart Association's journal Circulation.

18 Jun 2018

Gene editing technology predicts heart disease risk

Scientists could now use gene editing and stem cell technologies to predict whether carrying a specific gene variant increases the risk of heart disease.

18 Jun 2018

Novel compound as effective as FDA-approved antibiotics for treating deadly infections

Purdue University researchers have identified a new compound that in preliminary testing has shown itself to be as effective as antibiotics approved by the Food and Drug Administration to treat life-threatening infections while also appearing to be less susceptible to bacterial resistance.

18 Jun 2018

Study suggests state-of-the-art genomic testing for routine autopsy of stillbirths

Pregnancy loss and the death of a newborn baby are devastating events, and as of today around 25% of these perinatal deaths are unexplained despite autopsy.

18 Jun 2018

Researchers show feasibility of stem cell-derived organoids for developing gene therapy vectors

A new study that compared six of the most promising adeno-associated viral gene therapy vectors in human retinal organoid models showed clear distinctions in the efficiency of gene transfer to both retinal pigment epithelial and photoreceptor cells.

14 Jun 2018

Researchers produce snapshots of the cell's 'protein factories'

Berlin-based researchers have produced snapshots of the 'protein factories' of the cell. Their findings could set us on the path towards a new class of antibiotics.

14 Jun 2018

Novel approach induces cell death via dual targeting of DNA repair mechanism

Proteins commonly known as BRCA - short for BReast CAncer susceptibility gene- serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating cancer development.

13 Jun 2018

Immune response in RA patients linked to inflammation and joint damage

To diagnose rheumatoid arthritis, antibodies to the amino acid citrulline are commonly measured. A new study from Uppsala University shows that a broad mix of different antibodies in the joints is the dominant factor that can be associated with severe inflammation and joint damage.

12 Jun 2018

in vitro News and Research

New nuclear medicine approach shows potential for precision treatment of solid tumors

Novel theranostic agent designed for precise tumor diagnosis and therapy

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Studying The Effects of Microgravity on Muscle Mass

Researchers discover drug compound that inhibits movement of cancer cells

Researchers develop new guide for using mechanical stimulation to enhance tissue-engineered cartilage

Researchers create revolutionary model to study pulmonary diseases

Multidisciplinary Human-Focused Research

Quick adoption of new diagnostic tests could help NHS to save nearly £7 billion

Researchers invent medical device for proliferation, differentiation of neural stem cells

Study: Effects of in vitro fertilization depend on genetic variation inherited from parents

Researchers develop new method to preserve fertility in boys with prepubertal cancer

Study combines gene editing and stem cell technologies to predict person’s risk for heart disease

Gene editing technology predicts heart disease risk

Novel compound as effective as FDA-approved antibiotics for treating deadly infections

Study suggests state-of-the-art genomic testing for routine autopsy of stillbirths

Researchers show feasibility of stem cell-derived organoids for developing gene therapy vectors

Researchers produce snapshots of the cell's 'protein factories'

Novel approach induces cell death via dual targeting of DNA repair mechanism

Immune response in RA patients linked to inflammation and joint damage

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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