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New test detects Parkinson's disease before symptoms appear

In the development of Parkinson's disease (PD), the changes that will lead to neurodegeneration take place in the brain long before patients show any symptoms.

8 Jan 2024

3D mini-organs from human fetal brain tissue unlock new frontier in brain research

Scientists have developed 3D mini-organs from human fetal brain tissue that self-organize in vitro. These lab-grown organoids open up a brand-new way of studying how the brain develops.

8 Jan 2024

Unraveling the brain-fat pathway that dictates aging in mice

In recent years, research has begun to reveal that the lines of communication between the body's organs are key regulators of aging.

8 Jan 2024

Portable light technique pinpoints brain activity for object recognition

The brain is not only the most complex organ of the human body, but also one of the most difficult to study.

8 Jan 2024

UCSF research lays the groundwork for preventing deafness

Researchers have found a gene that links deafness to cell death in the inner ear in humans – creating new opportunities for averting hearing loss.

8 Jan 2024

Bacterial "freight elevator" unpacked: How pathogens hide from the immune system

Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane.

8 Jan 2024

Growing tiny tumors in the lab for personalized lung cancer treatment

Lung cancer accounts for nearly 20% of annual cancer-related deaths worldwide. According to 2022 statistics from the Swiss Cancer League, nearly 5,000 new cases of lung cancer are reported in Switzerland each year.

8 Jan 2024

Genomic analysis of uncultured bacteria from patients identifies more than thirty new species

Unknown germs are a common occurrence in hospitals. Researchers at the University of Basel have spent many years collecting and analyzing them.

8 Jan 2024

Introducing Teledyne LABS

A new brand and website for several well-known laboratory instrument brands.

From Teledyne LABS 8 Jan 2024

Research reveals post-Christmas cholesterol spike: Expert offers rescuing resolutions

Many of us have eaten too much of the wrong foods over Christmas, while seldom leaving the sofa. A leading testing expert reveals four realistic New Year’s Resolutions to help us recover from festive feasts.

8 Jan 2024

Does SARS-CoV-2's ability to infect humans stem from its evolutionary past?

Study challenges the hypothesis of genetic recombination in SARS-CoV-2's evolution, suggesting its ancestral virus already possessed human-infecting traits, based on analyses of over 100 viral genomes.

7 Jan 2024

University of Louisville scientists aim to disarm Yersinia pestis, the bubonic plague bacteria

When the body encounters bacteria, viruses or harmful substances, its innate immune cells, neutrophils, assemble at the site to combat the invader.

5 Jan 2024

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment.

5 Jan 2024

Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code.

5 Jan 2024

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Compounds that obstruct the "landing gear" of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19, a study published today and led by Dana-Farber Cancer Institute scientists shows.

5 Jan 2024

Uncovering the true culprit behind nanofiber-induced lung disease

The pathogenic potential of inhaling the inert fibrous nanomaterials used in thermal insulation (such as asbestos or fiberglass) is actually connected not to their chemical composition, but instead to their geometrical characteristics and size.

5 Jan 2024

YAP and TAZ proteins guide bone development in the womb

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

4 Jan 2024

Anti-CTLA-4 nanobodies offer promising strategy to prevent colitis in cancer immunotherapy

Microbiota-reactive T cells trigger colitis in mice harboring the microbiota of wild-caught mice following CTLA-4 blockade, according to a new study that reveals a major mechanism by which anti-CTLA-4 antibodies induce inflammatory toxicities during antitumor immune checkpoint inhibitor therapies.

4 Jan 2024

USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

4 Jan 2024

Sample type and time of collection play a role in the diagnosis of scrub typhus

Announcing a new article publication for Zoonoses journal. Scrub typhus (ST) is an acute febrile illness caused by Orientia tsutsugamushi. Laboratory tests are needed to confirm the diagnosis when the characteristic eschar is absent.

4 Jan 2024

Laboratory News and Research

New test detects Parkinson's disease before symptoms appear

3D mini-organs from human fetal brain tissue unlock new frontier in brain research

Unraveling the brain-fat pathway that dictates aging in mice

Portable light technique pinpoints brain activity for object recognition

UCSF research lays the groundwork for preventing deafness

Bacterial "freight elevator" unpacked: How pathogens hide from the immune system

Growing tiny tumors in the lab for personalized lung cancer treatment

Genomic analysis of uncultured bacteria from patients identifies more than thirty new species

Introducing Teledyne LABS

Research reveals post-Christmas cholesterol spike: Expert offers rescuing resolutions

Does SARS-CoV-2's ability to infect humans stem from its evolutionary past?

University of Louisville scientists aim to disarm Yersinia pestis, the bubonic plague bacteria

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Uncovering the true culprit behind nanofiber-induced lung disease

YAP and TAZ proteins guide bone development in the womb

Anti-CTLA-4 nanobodies offer promising strategy to prevent colitis in cancer immunotherapy

USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

Sample type and time of collection play a role in the diagnosis of scrub typhus

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