Research News and Research

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Smoking continues to be a leading cause of cancer-related death

A new study led by researchers at the American Cancer Society (ACS) reports nearly 123,000 cancer deaths, or close to 30 percent of all cancer deaths, were from cigarette smoking in the United States in 2019, leading to more than two million Person-Years of Lost Life (PYLL) and nearly $21 billion in annual lost earnings. These losses were disproportionately higher in states with weaker tobacco control policies in the South and Midwest. The results were published today in the International Journal of Cancer.

11 Aug 2022

Adults who use cannabis daily do not perceive smoking as harmful, study finds

A growing number of Americans are using cannabis as it becomes legalized for recreational use in a rapidly increasing number of U.S. states. Questions abound about what impact legalization will have on adult and youth health.

11 Aug 2022

Repurposed drug shows promise as potential new treatment for motor neuron disease

A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND), according to a new study.

11 Aug 2022

Interferon beta reduces binding of three components to RBCs, study finds

Drugs called interferon betas are common treatments for multiple sclerosis (MS), reducing relapses and slowing motor function decline. Interferon beta, a protein known to contain a zinc binding pocket, is thought to reduce proinflammatory molecules and even increase production of anti-inflammatory species in MS patients.

11 Aug 2022

Study aims to understand how female fertility is established at the molecular level

Fertility is finite for mammalian females. From birth, females possess a limited number of primordial follicles, collectively called the ovarian reserve. Within each follicle is an oocyte that eventually becomes an egg. But with age, the follicles in the ovarian reserve decrease.

11 Aug 2022

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable.

11 Aug 2022

Study quantifies the prognostic accuracy of two protein biomarkers

Blood tests taken within 24 hours of a traumatic brain injury (TBI) flag which patients are likely to die and which patients are likely to survive with severe disability, according to a study headed by UC San Francisco, the University of Pennsylvania and the University of Michigan. Their results -- available within minutes -- may confirm the need for prompt surgical interventions or may help guide conversations with families in cases of devastating injury.

11 Aug 2022

Study finds high level of resilience among children and adolescents living with glaucoma

Children and adolescents living with glaucoma develop a high level of emotional and social resilience to cope with this rare, chronic eye condition, a new Flinders University study reveals.

11 Aug 2022

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

In a new University of California, Irvine-led study, researchers define how the circadian clock influences cell growth, metabolism and tumor progression.

11 Aug 2022

Gene expression in male and female brains become more similar with age, study says

When male and female fruit flies age, their brains become desexualized. Age-related changes take place in both sexes, but the male brain becomes feminized to a larger extent than the female brain becomes masculinized. This is the conclusion of a study performed by a research group at Linköping University. The findings are published in the journal Proceedings of the Royal Society of London B.

11 Aug 2022

International medical experts aim to use biomarker-based approaches to advance precision medicine

The diagnostics company SphingoTec GmbH (SphingoTec), announces that, during the 4th Scientific Symposium held near Potsdam, Germany, international medical experts discussed the latest developments in diagnostic and therapeutic innovations for advancing precision medicine in critically ill patients.

11 Aug 2022

Collagen XII likely to be a potential marker for patients at high risk of metastatic relapse

Collagen type XII plays a key role in regulating the organization of the tumor matrix, reveals a new study from the Garvan Institute of Medical Research. A team of scientists led by Associate Professor Thomas Cox, Head of the Matrix and Metastasis lab, also discovered that high levels of collagen XII can trigger breast cancer cells to spread from the tumor to other parts of the body, a process known as metastasis.

11 Aug 2022

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Stimulator of interferon genes, or STING, helps regulate immune activation. Thus, drugs that activate STING are being tested as a form of cancer immunotherapy and for treating certain infections.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Study: Family caregivers in the UK felt 'powerless, voiceless and choiceless' during the early pandemic

Family caregivers in the UK were marginalised during the pandemic, and vulnerable older people were let down by the health system, a new study has found.

11 Aug 2022

Traditional Chinese medicine reduces severity of radiation-induced gastrointestinal mucositis in rats

For tens of thousands of Australians who receive radiotherapy as part of their cancer treatment, mucositis is a serious side effect that may cause inflammation, ulcers, diarrhea, nausea and vomiting, abdominal pain and bloating.

11 Aug 2022

New compound proves to be potent against more than 300 drug-resistant bacteria

Urinary tract infections are common, yet are increasingly tough to treat because the bacteria that cause them are becoming resistant to many antibiotics.

10 Aug 2022

How ultraprocessed foods affect gut microbiome and health

Researchers describe the association between the consumption of ultraprocessed foods and chronic medical conditions.

10 Aug 2022

Pressure ulcers' number and severity found to be underreported by U.S. nursing homes

Researchers at the University of Chicago have found that the number and severity of pressure ulcers suffered by Medicare residents in U.S. nursing homes is substantially underreported, leading to unreliable data that many consumers use to determine where to receive long- or short-term care.

10 Aug 2022

Prenatal bisphenol A exposure may affect brain volume in children

Scientists report that gestational exposure to low levels of bisphenol A may induce structural alterations in some fetal brain regions.

10 Aug 2022

Research News and Research

Smoking continues to be a leading cause of cancer-related death

Adults who use cannabis daily do not perceive smoking as harmful, study finds

Repurposed drug shows promise as potential new treatment for motor neuron disease

Interferon beta reduces binding of three components to RBCs, study finds

Study aims to understand how female fertility is established at the molecular level

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

Study quantifies the prognostic accuracy of two protein biomarkers

Study finds high level of resilience among children and adolescents living with glaucoma

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

Gene expression in male and female brains become more similar with age, study says

International medical experts aim to use biomarker-based approaches to advance precision medicine

Collagen XII likely to be a potential marker for patients at high risk of metastatic relapse

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Study: Family caregivers in the UK felt 'powerless, voiceless and choiceless' during the early pandemic

Traditional Chinese medicine reduces severity of radiation-induced gastrointestinal mucositis in rats

New compound proves to be potent against more than 300 drug-resistant bacteria

How ultraprocessed foods affect gut microbiome and health

Pressure ulcers' number and severity found to be underreported by U.S. nursing homes

Prenatal bisphenol A exposure may affect brain volume in children

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