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Study shows metastasizing cancer cells undergo molecular change during EMT

For the majority of cancer patients, it's not the primary tumor that is deadly, but the spread or "metastasis" of cancer cells from the primary tumor to secondary locations throughout the body that is the problem. That's why a major focus of contemporary cancer research is how to stop or fight metastasis.

14 Aug 2013

Proton therapy provides organ-sparing treatment option for children with neuroblastoma

Proton therapy, using high-energy subatomic particles, may offer a precise, organ-sparing treatment option for children with high-risk forms of neuroblastoma. For patients in a new study of advanced radiation treatment, proton therapy spared the liver and kidneys from unwanted radiation, while zeroing in on its target.

14 Aug 2013

Doctors create new route to implant artificial heart valve

Doctors at Henry Ford Hospital have created a new route to the heart to implant an artificial heart valve by temporarily connecting major blood vessels that do not normally intersect.

14 Aug 2013

Poly(lactic-co-glycolic acid) conduits suitable for sciatic nerve injury repair

The conventional method for repair of peripheral nerve injury is autogenous nerve grafting, but sources of autogenous nerve are limited. Furthermore, neurological deficits in the donor site and painful neuroma can occur following surgery.

14 Aug 2013

PSA screening shows low-grade prostate cancers do not progress to higher grade over time

Prostate cancer aggressiveness may be established when the tumor is formed and not alter with time, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.

14 Aug 2013

New test hints 3 sodas daily hurt lifespan, reproduction in mice

When mice ate a diet of 25 percent extra sugar - the mouse equivalent of a healthy human diet plus three cans of soda daily - females died at twice the normal rate and males were a quarter less likely to hold territory and reproduce, according to a toxicity test developed at the University of Utah.

14 Aug 2013

Neural stem cells transplantation in tumor-bearing rats can hinder tumor cell growth

Neural stem cells transplanted into tumor-bearing rats can hinder tumor cell growth and prolife-ration; however, the mechanism remains unclear.

14 Aug 2013

New discovery to fight against antibiotic-resistant superbugs

The fight against antibiotic-resistant superbugs has taken a step forward thanks to a new discovery by scientists at The University of Nottingham.

14 Aug 2013

Virus-derived particles developed to kill human blood cancer cells, eradicate disease in mice

Ottawa researchers have developed unique virus-derived particles that can kill human blood cancer cells in the laboratory and eradicate the disease in mice with few side effects. The study is published in Blood Cancer Journal by co-senior authors Drs. David Conrad and John Bell of the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa (uOttawa).

14 Aug 2013

Early surgery offers long-term survival, lowers risk of heart failure in mitral valve regurgitation patients

Patients with severe mitral valve regurgitation who are otherwise healthy should have mitral valve repair surgery sooner rather than later, even if they feel no symptoms, a Mayo Clinic-led study by U.S. and European researchers found.

14 Aug 2013

Risk of infectious gastroenteritis and IBD relapse increases during heat wave periods

Swiss researchers report an increase risk of inflammatory bowel disease (IBD) relapse in patients during heat wave periods. The study published in The American Journal of Gastroenterology also found an increase of infectious gastroenteritis during heat waves, with the strongest impact following a 7 day lag time after the heat wave.

14 Aug 2013

SIgN discovers strategy that cripples ability of dengue virus to escape host immune system

A new strategy that cripples the ability of the dengue virus to escape the host immune system has been discovered by A*STAR's Singapore Immunology Network (SIgN). This breakthrough strategy opens a door of hope to what may become the world's first universal dengue vaccine candidate that can give full protection from all four serotypes of the dreadful virus.

14 Aug 2013

Study reveals cancer in humans linked with high amounts of proteins responsible for cells division

Cancer in humans is frequently associated with unusually high amounts of one or more proteins responsible for controlling the rate at which cells divide. As an example, excessive amounts of the cyclin-dependent kinase CDK6 are often found in types of cancer such as lymphoma.

14 Aug 2013

Cultural mythologies strongly influence women’s expectations during pregnancy

Morning sickness, shiny hair and bizarre and intense cravings for pickles and ice cream -- what expectations do pregnant women impose on their bodies, and how are those expectations influenced by cultural perspectives on pregnancy? University of Cincinnati researcher Danielle Bessett, an assistant professor of sociology, presented her research at the 108th annual meeting of the American Sociological Association in New York, N.Y.

14 Aug 2013

Chemical compound prevents fungal cells from adhering to surfaces

Targeting serious and sometimes deadly fungal infections, a team of researchers at Worcester Polytechnic Institute (WPI) and the University of Massachusetts Medical School (UMMS) has discovered a chemical compound that prevents fungal cells from adhering to surfaces, which, typically, is the first step of the infection process used by the human pathogen Candida albicans (C. albicans).

14 Aug 2013

Three winners announced for biomedical engineering design competition in DEBUT challenge

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13 Aug 2013

Researchers discover why early pregnancy reduces breast cancer

An international scientific collaborative led by the Harvard Stem Cell Institute's Kornelia Polyak, MD, PhD, has discovered why women who give birth in their early twenties are less likely to eventually develop breast cancer than women who don't, triggering a search for a way to confer this protective state on all women.

13 Aug 2013

X-linked methyl-CpG protein may be potential target for treatment of Parkinson's

X-linked methyl-CpG binding protein 2 plays important role in the regulation of neuronal development, proliferation and maturation, and synaptic regeneration and apoptosis.

13 Aug 2013

Researchers identify clear genetic risk factors in patients with severe epilepsy

Neurologists and epilepsy researchers from NYU Langone Medical Center were among scientists who have 329 random genetic mutations associated with two of the most severe forms of epilepsy, according to a paper published today in Nature.

13 Aug 2013

Viewpoints: Obama overlooking legal constraints on employer mandate delay; Bush's 'unnecessary' heart procedure; discrimination against people with mental illnesses

In his Friday remarks, Mr. Obama also claimed that he had the "executive authority" for the mandate delay. But if he really believes that, then why did he say he would normally ask for a legislative "tweak." Either the fix requires legislation or it doesn't. His comments are certainly revealing about his attitudes on Presidential power and the constraints of the U.S. Constitution. Article II, Section 3 instructs him to take care that the laws be faithfully executed, not merely what he thinks is "the essence" of laws (8/10).

13 Aug 2013

Hospital News and Research

Study shows metastasizing cancer cells undergo molecular change during EMT

Proton therapy provides organ-sparing treatment option for children with neuroblastoma

Doctors create new route to implant artificial heart valve

Poly(lactic-co-glycolic acid) conduits suitable for sciatic nerve injury repair

PSA screening shows low-grade prostate cancers do not progress to higher grade over time

New test hints 3 sodas daily hurt lifespan, reproduction in mice

Neural stem cells transplantation in tumor-bearing rats can hinder tumor cell growth

New discovery to fight against antibiotic-resistant superbugs

Virus-derived particles developed to kill human blood cancer cells, eradicate disease in mice

Early surgery offers long-term survival, lowers risk of heart failure in mitral valve regurgitation patients

Risk of infectious gastroenteritis and IBD relapse increases during heat wave periods

SIgN discovers strategy that cripples ability of dengue virus to escape host immune system

Study reveals cancer in humans linked with high amounts of proteins responsible for cells division

Cultural mythologies strongly influence women’s expectations during pregnancy

Chemical compound prevents fungal cells from adhering to surfaces

Three winners announced for biomedical engineering design competition in DEBUT challenge

Researchers discover why early pregnancy reduces breast cancer

X-linked methyl-CpG protein may be potential target for treatment of Parkinson's

Researchers identify clear genetic risk factors in patients with severe epilepsy

Viewpoints: Obama overlooking legal constraints on employer mandate delay; Bush's 'unnecessary' heart procedure; discrimination against people with mental illnesses

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

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