Knee Replacement News and Research

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Lateral wedge insoles are not effective in reducing knee pain in osteoarthritis patients

Although a pooling of data from 12 studies showed a statistically significant association between use of lateral wedge insoles and lower pain in medial knee osteoarthritis, among trials comparing wedge insoles with neutral insoles, there was no significant or clinically important association between use of wedge insoles and reduction in knee pain, according to a study in the August 21 issue of JAMA.

21 Aug 2013

Dermatology researcher receives NIH grant to investigate role of nervous system in psoriasis

Dermatology researcher Nicole Ward, PhD, has earned her third National Institutes of Health grant in a year - including two that scored in the first percentile. With this most recent award, an R21, she will investigate the role the nervous system plays in psoriasis - an inflammatory autoimmune disease characterized by raised areas of red, scaly, itchy and sometimes painful patches of skin.

17 Aug 2013

Osteoarthritis research: an interview with Dr Deborah Mason, Cardiff University

Osteoarthritis is an extremely common condition affecting about 8 million people in the UK. The elderly are particularly susceptible, with up to 45% of people over 65 years, having the disease.

14 Aug 2013

ConforMIS expands Series E financing to $167.7 million

ConforMIS, Inc., a privately held medical device company pioneering patient-specific orthopedic implants, announced today it has expanded its Series E financing to $167.7 million with participation from top-tier Sovereign Wealth Funds, Government Investment Funds and Private Equity Funds in the U.S., Europe, Asia and the Middle East.

3 Aug 2013

Forced-air patient warming systems may affect airflows in OR; increase exposure to airborne contaminants

Forced-air systems used to keep patients warm during surgery may affect the performance of operating room (OR) ventilation systems-potentially increasing exposure to airborne contaminants, reports a study in the August issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

25 Jul 2013

New noninvasive technique for tracking stem cells after transplantation

A new, noninvasive technique for tracking stem cells after transplantation - developed by a cross-disciplinary team of radiologists, chemists, statisticians and materials scientists at the Stanford University School of Medicine - could help surgeons determine whether a procedure to repair injured or worn-out knees is successful.

12 Jul 2013

Bristol-Myers Squibb, Pfizer announce FDA acceptance of Eliquis sNDA for review

Bristol-Myers Squibb Company and Pfizer Inc. today announced that the U.S. Food and Drug Administration has accepted for review a Supplemental New Drug Application for Eliquis (apixaban), for the prophylaxis of deep vein thrombosis, which may lead to pulmonary embolism, in adult patients who have undergone hip or knee replacement surgery.

11 Jul 2013

Study shows that PCCs can reverse blood thinning effects of XARELTO in healthy subjects

Janssen Research & Development, LLC announced today results of an open label, single-center, parallel group study showing that a type of medication called prothrombin complex concentrates can reverse the blood thinning effects of XARELTO (rivaroxaban) in healthy subjects.

2 Jul 2013

Janssen receives complete response letter from FDA for XARELTO sNDA

Janssen Research & Development, LLC today announced the U.S. Food and Drug Administration has issued a complete response letter for the supplemental New Drug Application for XARELTO (rivaroxaban) to reduce the risk of stent thrombosis in patients with acute coronary syndrome.

28 Jun 2013

Companies examine ways to cut health costs, deal with Obamacare

The New York Times explores how employers are wrestling with approaches to health costs, as well as the health law's new requirements.

25 Jun 2013

Boehringer submits application to EMA for use of Pradaxa for treatment of acute DVT, PE

Boehringer Ingelheim today announced the submission of an application to the European Medicines Agency (EMA) for use of Pradaxa (dabigatran etexilate) for the treatment of acute deep vein thrombosis (DVT) and pulmonary embolism (PE) and the prevention of recurrent DVT and PE.

24 Jun 2013

New drug target may prevent consequences of ACL tear in athletes

Striking the likes of Chicago Bulls' Derrick Rose, L.A. Lakers' Kobe Bryant and Detroit Tigers' Victor Martinez, tears in the anterior cruciate ligament (ACL) are one of the most rampant and serious knee injuries among athletes.

14 Jun 2013

Two studies shed light on joint replacement outcomes in rheumatoid arthritis patients

Two new studies by researchers at Hospital for Special Surgery have shed light on joint replacement outcomes in patients with rheumatoid arthritis. One study overturns the common belief that RA patients have worse outcomes after a total knee replacement than patients who undergo the operation for osteoarthritis. The other study demonstrates that RA patients who undergo a total hip replacement were as likely to have significant improvements in function and pain as patients with osteoarthritis, even though they did not do as well.

12 Jun 2013

Arthritis estimated to cost $33 billion annually to the Canadian economy

Siena Pacheco is five years old, and enjoys swimming and riding her bike. Sheila Stone has a few years on Siena, but she also enjoys swimming and cycling, and the kindergarten teacher insists she still has the spirit of a five-year-old.

10 Jun 2013

$Epidural steroid injection is associated with increased spinal fracture$

Epidural steroid injection is associated with increased spinal fracture

Most aging adults will experience back pain or a spinal disorder at some time in their life. In fact, about 25.8 million visits were made to physicians' offices due to primary back problems. Treatment focuses on pain relief and is available in both non-surgical (medication or physical therapy) and surgical forms.

7 Jun 2013

Revised CPG on treatment of osteoarthritis of the knee addresses two key changes

The American Academy of Orthopaedic Surgeons recently released its revised clinical practice guideline on the treatment of osteoarthritis of the knee, addressing two key changes.

5 Jun 2013

START team examines surgery-free treatment for people with knee osteoarthritis

Lindsay Tise is not the guy you would expect to see pumping iron at the gym. At 94 years old, he suffers from knee osteoarthritis, a debilitating yet common ailment for older Americans that makes physical activity both difficult and painful.

29 May 2013

Lower-income individuals are more likely to report dissatisfaction with knee replacement surgery

Knee replacement surgery is a very common procedure. However, it does not always resolve function or pain in all the recipients of new knees.

22 May 2013

Blue Belt Technologies, DJO Surgical announce implant partnership

Blue Belt Technologies, Inc., an innovative medical technology company commercializing robotic solutions for orthopedic surgery, announces an implant partnership with DJO Surgical, a DJO Global Company.

20 May 2013

GE Healthcare introduces novel MR imaging technology

At an event held today at Hospital for Special Surgery, GE Healthcare introduced MAVRIC SL, a novel magnetic resonance imaging technique designed to address the growing clinical need to more accurately image soft tissue and bone in patients with MR Conditional-labeled implants, such as joint replacements and other instrumentation.

16 May 2013