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Targeted drug delivery now possible using nanoparticle-apatamer conjugates

Ground-breaking results from researchers at Harvard Medical School and Massachusetts Institute of Technology (MIT), USA, disclosed at the 13th European Cancer Conference (ECCO) have shown for the first time that targeted drug delivery is possible using nanoparticle-apatamer conjugates.

3 Nov 2005

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

Ground-breaking results from researchers at Harvard Medical School and Massachusetts Institute of Technology (MIT), USA, disclosed at the 13th European Cancer Conference (ECCO) in Paris have shown for the first time that targeted drug delivery is possible using nanoparticle-apatamer conjugates.

1 Nov 2005

Possible toxic damage from inhaled nanoparticles

A physicist and a medical researcher at the University of Leicester have received a grant of £100,000 from the Engineering and Physical Sciences Research Council to look at possible toxic damage from inhaled nanoparticles used for a range of everyday purposes.

27 Oct 2005

Number of color-sensitive cones in the human retina differs dramatically among people

First-ever images of living human retinas have yielded a surprise about how we perceive our world.

25 Oct 2005

New model important step toward understanding the molecular basis of cell membrane mechanics

A human red blood cell is a dimpled ballerina, ceaselessly spinning, tumbling, bending, and squeezing through openings narrower than its width to dispense life-giving oxygen to every corner of the body.

24 Oct 2005

Scientists discover molecular structure related to cell growth and cancer

Researchers discovered a special type of molecular structure that helps keep genes properly turned off until the structure is ejected from those genes in a regulated manner to help turn the genes on.

23 Oct 2005

Method to count the absolute number of individual protein molecules inside a living cell

Yale researchers have reported a method to count the absolute number of individual protein molecules inside a living cell, and to measure accurately where they are located, two basic hurdles for studying biology quantitatively.

20 Oct 2005

New prostate cancer test far more accurate

At present in order to predict prostate cancer outcomes, doctors rely on measures that suggest how far the tumour has spread and how abnormal the cancer cells appear under the microscope.

18 Oct 2005

New findings on brain tumors called ependymomas

Brain tumors called ependymomas that occur in different parts of the central nervous system appear to arise from subpopulations of stem cells called radial glia cells (RGCs), according to investigators at St. Jude Children's Research Hospital. The discovery explains why some identical-looking ependymomas are actually distinctly different diseases, the researchers said.

17 Oct 2005

Curry spice appears to shut down a protein active in the spread of breast cancer

Curcumin, the main ingredient of turmeric and the compound that gives curry its mustard-yellow color, inhibits metastasis to the lungs of mice with breast cancer, report researchers at The University of Texas M. D. Anderson Cancer Center

16 Oct 2005

Performing a sentinel node biopsy prior to mastectomy and reconstruction gives best results

Altering the standard step-by-step procedure that takes women facing a mastectomy from diagnosis to surgery to reconstruction can improve the process and help in determining if immediate reconstruction is the best course of action, according to new research from the University of North Carolina at Chapel Hill.

10 Oct 2005

New insights that advance the current model of protein motility and muscle contraction

Scientists from the Burnham Institute for Medical Research and the University of Vermont have captured the first 3-dimensional (3D) atomic-resolution images of the motor protein myosin V as it "walks" along other proteins, revealing new structural insights that advance the current model of protein motility and muscle contraction.

3 Oct 2005

Clostridium botulinum exposed

A discovery by Institute of Food Research (IFR) scientists is set to improve the food industry’s ability to predict foodborne botulism.

28 Sep 2005

Pulsing heart cell provides clues into how heart disease develops

A pulsing heart cell is giving Oregon Health & Science University researchers insight into how it sends and receives signals, and that's providing clues into how heart disease and other disorders develop.

27 Sep 2005

Discovery of molecule that causes transverse myelitis

Hopkins researchers have discovered a single molecule that is a cause of an autoimmune disease in the central nervous system, called transverse myelitis (TM), that is related to multiple sclerosis.

26 Sep 2005

Researchers gain insights into how malaria pathogen destroys the cells in which it resides

By specially tagging the outer and inner membranes of red blood cells infected with the malaria parasite and tracking the cellular changes that precede the cell bursting event that disperses parasites to other blood cells, a group of researchers has deepened our understanding of how the malaria pathogen destroys the cells in which it resides.

26 Sep 2005

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

Their findings, which may point to new approaches to developing improved treatment options for the disease, are published in the journal Nature.

26 Sep 2005

Extreme gene pin-pointed

One teenager likes to snowboard off a cliff. Another prefers to read a book and wouldn't think of trading places. Why these differences exist is a mystery, but for the first time researchers have identified a possible genetic explanation behind risk-seeking behavior.

26 Sep 2005

New way to create a permanent chemical bond between antibiotics and titanium

Infections associated with inserting a medical device can be devastating, painful, and cause prolonged disability, costing tens of thousands of dollars.

26 Sep 2005

Dilute bleach neutralizes the mold allergens that cause most mold-related health complaints

Researchers at National Jewish Medical and Research Center have demonstrated that dilute bleach not only kills common household mold, but may also neutralize the mold allergens that cause most mold-related health complaints.

22 Sep 2005

Microscopy News and Research

Targeted drug delivery now possible using nanoparticle-apatamer conjugates

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

Possible toxic damage from inhaled nanoparticles

Number of color-sensitive cones in the human retina differs dramatically among people

New model important step toward understanding the molecular basis of cell membrane mechanics

Scientists discover molecular structure related to cell growth and cancer

Method to count the absolute number of individual protein molecules inside a living cell

New prostate cancer test far more accurate

New findings on brain tumors called ependymomas

Curry spice appears to shut down a protein active in the spread of breast cancer

Performing a sentinel node biopsy prior to mastectomy and reconstruction gives best results

New insights that advance the current model of protein motility and muscle contraction

Clostridium botulinum exposed

Pulsing heart cell provides clues into how heart disease develops

Discovery of molecule that causes transverse myelitis

Researchers gain insights into how malaria pathogen destroys the cells in which it resides

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

Extreme gene pin-pointed

New way to create a permanent chemical bond between antibiotics and titanium

Dilute bleach neutralizes the mold allergens that cause most mold-related health complaints

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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