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Study may lead to personalized treatments for mitochondrial energy disorders

Researchers have identified a master network of signaling molecules that acts like a "fuse box" to regulate the cellular effects of defective energy flow in mitochondrial respiratory chain diseases—a diverse set of difficult-to-treat genetic-based energy disorders.

25 Jul 2013

Mechanical tension increases nerve density, nerve growth factor expression in scar tissue

Scars are prone to appear at high tension parts, such as the sternum, shoulder and back, which are serious clinical problems. Surgeons reduce scar formation through Z, W, V-Y flap variation and reducing blade tension, but its specific mechanism are still not very clear.

25 Jul 2013

Study shows 90% of dementia cases in China go undetected; high level in rural areas

An international team of researchers has found that over 90 percent of dementia cases in China go undetected, with a high level of undiagnosed dementia in rural areas. The team of public health experts led by Dr Ruoling Chen at King's College London argues that more mental health education targeting high-risk populations is now needed to improve diagnosis rates, and increase support for sufferers and their families.

25 Jul 2013

Manchester scientists treat fatal genetic brain disease using stem cell gene therapy

Scientists from The University of Manchester have used stem cell gene therapy to treat a fatal genetic brain disease in mice for the first time.

From The University of Manchester 25 Jul 2013

Randomized trial examines purging of tumor cells from stem cells prior to transplantation in neuroblastoma patients

Judith Villablanca, MD, of The Saban Research Institute of Children's Hospital Los Angeles, Susan Kreissman, MD, of Duke University Medical Center, and colleagues reported the results of a randomized, phase 3 clinical trial conducted by the Children's Oncology Group examining the effect of selectively removing (purging) tumor cells from blood stem cells before they are transplanted back into patients with high-risk neuroblastoma following high-dose chemotherapy.

25 Jul 2013

Stem cell-based epilepsy approach may help in search for better medicines to treat seizure disorders

A new stem cell-based approach to studying epilepsy has yielded a surprising discovery about what causes one form of the disease, and may help in the search for better medicines to treat all kinds of seizure disorders.

25 Jul 2013

State abortion clinic restrictions could impact women's health care access

Stateline reports that abortion opponents are advancing new clinic standards that may be impossible to meet. Abortion rights supporters fear these rules could force many clinics to close, making it more difficult for some women to get a broad array of health care services.

25 Jul 2013

Study reveals that black women with breast cancer continue to have lower survival rate

In an analysis of 5-year survival rates among black and white women diagnosed with breast cancer between 1991 and 2005, black women continued to have a lower rate of survival, with most of the difference related to factors including poorer health of black patients at diagnosis and more advanced disease, rather than treatment differences, according to a study in the July 24/31 issue of JAMA.

25 Jul 2013

Mayo Clinic welcomes Trinity Health as newest member of its Network

In a move designed to strengthen the delivery and quality of health care in northwest North Dakota, Mayo Clinic today welcomes Trinity Health as the newest member of the Mayo Clinic Care Network. As a member of the network, Trinity Health's physicians and other providers will have direct access to Mayo Clinic experts and clinical resources.

25 Jul 2013

Study reveals African bats may play a role in evolution of MERS-CoV predecessor viruses

The MERS-coronavirus is regarded as a dangerous novel pathogen: Almost 50 people have died from infection with the virus since it was first discovered in 2012. To date all cases are connected with the Arabian peninsula. Scientists from the University Bonn (Germany) and South Africa have now detected a virus in the faeces of a South African bat that is genetically more closely related to MERS-CoV than any other known virus.

25 Jul 2013

Nearly 1/2 of older adults undergoing surgery with general anesthesia have delirium in PACU

Close to half of older adults undergoing surgery with general anesthesia are found to have delirium in the postanesthesia care unit (PACU), according to a study in the August issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

25 Jul 2013

Researcher identify genetic mutation in Africans with HIV that puts them at higher risk for tuberculosis

A researcher from the Perelman School of Medicine at the University of Pennsylvania and colleagues have identified the genetic mutation in Africans with HIV that puts them at a much higher risk for tuberculosis (TB) infections.

25 Jul 2013

State highlights: Medicaid pilot project costs $32B more than expected

A selection of health policy stories from the District of Columbia, New York, Georgia, Minnesota, Illinois, North Carolina, Colorado and California.

24 Jul 2013

Innovative microsurgery technique helps prevent lymphedema in patients with breast cancer

A team of surgeons and members of the breast cancer program of the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital/Columbia University Medical Center is conducting a two-year pilot study of an innovative microsurgery technique coupled with imaging technology to not only prevent lymphedema but also potentially detect and treat it early.

24 Jul 2013

Cambridge Consultants help Clinigen Group to breathe new life into old drugs

Innovative product development and technology consultancy firm Cambridge Consultants has collaborated with Clinigen Group to create a new way of identifying fresh market applications for drugs nearing the end of their product lifecycle.

From Clinigen Group 24 Jul 2013

Liveprocess gains international presence

LiveProcess, the nation's leader in healthcare emergency preparedness and emergency management solutions, has gained an international presence, recently adding 60 new installations including facilities in Europe, the Middle East and Caribbean to its growing customer base.

24 Jul 2013

Mortality rates declining among dialysis patients despite rise in coronary artery disease, study finds

A new study led by researchers at the University of Limerick’s Graduate Entry Medical School has found that deaths among dialysis patients are falling despite a rise in coronary artery disease.

24 Jul 2013

Child cancer survival: an interview with Prof Kathy Pritchard-Jones, University College London

Back in the early 1960s, just before chemotherapy really started to be used, only about 30% of children survived cancer. That was mainly because they had cancers that were amenable to surgery.

24 Jul 2013

Academic hospitals have higher mammography recall rates than community radiology centers

A new study at Rhode Island Hospital has found that academic medical centers have higher rates of recall following mammography than community radiology centers. The recall rate is the frequency at which a radiologist interprets an examination as positive and the patient is instructed to return for more testing.

24 Jul 2013

Family and friends' fears of recurrence impact on patient's recovery after SAH

Researchers from Durham University and Kings College London (United Kingdom) and the University of Erlangen-N-rnberg (Germany) found that patients who have suffered a subarachnoid hemorrhage (SAH) may not recover psychosocially as well as expected if their significant other is excessively fearful about the possibility of SAH recurrence.

24 Jul 2013

Hospital News and Research

Study may lead to personalized treatments for mitochondrial energy disorders

Mechanical tension increases nerve density, nerve growth factor expression in scar tissue

Study shows 90% of dementia cases in China go undetected; high level in rural areas

Manchester scientists treat fatal genetic brain disease using stem cell gene therapy

Randomized trial examines purging of tumor cells from stem cells prior to transplantation in neuroblastoma patients

Stem cell-based epilepsy approach may help in search for better medicines to treat seizure disorders

State abortion clinic restrictions could impact women's health care access

Study reveals that black women with breast cancer continue to have lower survival rate

Mayo Clinic welcomes Trinity Health as newest member of its Network

Study reveals African bats may play a role in evolution of MERS-CoV predecessor viruses

Nearly 1/2 of older adults undergoing surgery with general anesthesia have delirium in PACU

Researcher identify genetic mutation in Africans with HIV that puts them at higher risk for tuberculosis

State highlights: Medicaid pilot project costs $32B more than expected

Innovative microsurgery technique helps prevent lymphedema in patients with breast cancer

Cambridge Consultants help Clinigen Group to breathe new life into old drugs

Liveprocess gains international presence

Mortality rates declining among dialysis patients despite rise in coronary artery disease, study finds

Child cancer survival: an interview with Prof Kathy Pritchard-Jones, University College London

Academic hospitals have higher mammography recall rates than community radiology centers

Family and friends' fears of recurrence impact on patient's recovery after SAH

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

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