Bone Marrow News and Research

RSS

Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Statins can stimulate cardiac muscle cell regeneration, improve heart function

Statins, used widely to treat elevated cholesterol, have been shown to prevent progression of coronary narrowing and to have other beneficial effects on the heart, such as reducing inflammation, that are independent of cholesterol.

23 Feb 2009

B-cell clones as early markers for chronic lymphocytic leukemia

Testing of blood specimens may detect abnormal white blood cells in patients years before the chronic form of lymphocytic leukemia (CLL) develops, according to research published in the current issue of the New England Journal of Medicine.

22 Feb 2009

A stem cell bandage for your knee

Building on his previous work, Hollander and his team, which included Dr Wael Kafienah and Dr John Tarlton, announced in 2005 they had, for the first time ever, successfully grown human cartilage from a patient's own bone marrow stem cells.

18 Feb 2009

Trial of Quadramet (153 Samarium-lexidronam) in combo with Velcade shows positive results

Quadramet (153 Samarium-lexidronam) is a radioactive medication that targets the bone, specifically bone cancer, and is used to treat pain caused by cancer that has metastasized or spread to the bone.

15 Feb 2009

$Osteoblast cell injections accelerate fracture healing$

Osteoblast cell injections accelerate fracture healing

Long bone fractures heal faster after injections of bone-building cells.

11 Feb 2009

Bone marrow transplant patients may benefit from new immune research

Bone marrow transplant (BMT) researchers at The Medical College of Wisconsin Cancer Center in Milwaukee may have found a mechanism that could preserve the leukemia-killing effects of a transplant graft, while limiting the damage donor immune cells might do to the recipient host's vital organs.

11 Feb 2009

ViroPharma reports results of trial for Maribavir in bone marrow transplant patients

ViroPharma Incorporated has announced that its Phase 3 trial evaluating maribavir used as prophylaxis in allogeneic stem cell, or bone marrow, transplant (SCT) patients did not achieve its primary endpoint.

10 Feb 2009

Research to explore why lupus therapies work for some, not others

The results should shed light not only on the mechanisms behind the disease, but more broadly on the workings of our immune system, especially how our bodies churn out and "train" key combat-ready immune cells, called B-cells.

8 Feb 2009

Sangamo BioSciences starts trial of CCR5-ZFP therapeutic to treat HIV/AIDS

Sangamo BioSciences, Inc. has announced that its collaborators at the University of Pennsylvania have opened a Phase 1 clinical trial to evaluate SB-728-T for the treatment of HIV/AIDS.

5 Feb 2009

Cultured cells from the bone marrow can heal nerves in diabetes model

Transplanting cells that replenish blood vessels can also restore nerve function in an animal model of diabetic neuropathy, Emory researchers have found.

5 Feb 2009

Researchers identify a cell type that limits brain damage after a stroke

A research team including Serge Rivest of University Laval's Faculty of Medicine has demonstrated the existence of a type of cells that limits brain damage after a stroke.

29 Jan 2009

New study looks at childhood leukaemia, caffeine intake and pregnancy

A study led by Dr Marcus Cooke at the University of Leicester and funded by World Cancer Research Fund (WCRF) UK is looking at whether consuming caffeine during pregnancy might affect the unborn baby's risk of developing leukaemia in childhood.

27 Jan 2009

New understanding on how aging causes broken bones to heal slowly

Researchers have unraveled crucial details of how aging causes broken bones to heal slowly, or not at all, according to study results published today in the Journal of Bone and Mineral Research.

19 Jan 2009

Bone marrow stem cells used to regenerate skin

A new study suggests that adult bone marrow stem cells can be used in the construction of artificial skin.

15 Jan 2009

Algeta completes phase II trial with Alpharadin for treating bone metastases in advanced prostate cancer

Algeta ASA has announced that with the results of the BC1-04 study reported today it has completed its comprehensive phase II clinical program evaluating Alpharadin (radium-223) as a new treatment for bone metastases in patients with hormone-refractory prostate cancer (HRPC).

15 Jan 2009

Gene therapy kills brain tumors through selective recruitment of immune cells

Scientists seeking to harness the power of the immune system to eradicate brain tumors face two major hurdles: recruiting key immune cells called dendritic cells into areas of the brain where they are not naturally found and helping them recognize tumor cells as targets for attack.

13 Jan 2009

Researchers find molecular origin of blood stem cells

A research team led by Nancy Speck, PhD, Professor of Cell and Developmental Biology at the University of Pennsylvania School of Medicine, has identified the location and developmental timeline in which a majority of bone marrow stem cells form in the mouse embryo.

12 Jan 2009

Discovery of new regulatory circuit controlling immune cell production in mice

Using a mouse model, researchers have shown that elevated levels of a small protein known as interleukin 7 (IL-7) plays a central role in regulating the production of a type of white blood cell that is required for effective immune responses.

12 Jan 2009

New hope for transplant recipients and AIDS patients

A researcher from the Université de Montréal and the Maisonneuve-Rosemont Hospital has discovered the mechanism that prevents the regeneration of CD4+ T lymphocytes, which are white cells that are required for the proper functioning of the immune system.

12 Jan 2009

Researchers trick bone marrow into releasing mesenchymal stem cells

Scientists have tricked bone marrow into releasing extra adult stem cells into the bloodstream, a technique that they hope could one day be used to repair heart damage or mend a broken bone, in a new study published today in the journal Cell Stem Cell.

9 Jan 2009