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Men with common genetic variant twice as likely to develop dementia

New research has found that men who carry a common genetic variant are twice as likely to develop dementia in their lifetime compared to women.

31 May 2025

Triplet therapy significantly improves survival in BRAF V600E-mutated metastatic colorectal cancer

First-line treatment with the triplet combination of encorafenib, cetuximab and mFOLFOX6 significantly improved survival compared to the standard of care in patients with BRAF V600E-mutated metastatic colorectal cancer, according to new data from the Phase III BREAKWATER trial led by researchers from The University of Texas MD Anderson Cancer Center.

30 May 2025

New trial offers hope for men with aggressive prostate cancer

Many men with aggressive prostate cancer can experience a high rate of recurrence despite treatment.

30 May 2025

Research uncovers new links between blood lipid profiles and risk of developing Alzheimer's

People who are at higher risk for heart disease also seem more likely to develop dementia.

30 May 2025

New AI test identifies prostate cancer patients who benefit from abiraterone

A new artificial intelligence (AI) test can identify which men with prostate cancer will benefit most from the life-extending drug abiraterone, in clinical trial results presented by scientists from UCL and the Institute of Cancer Research.

30 May 2025

Pitt professor wins NSF CAREER Award for AI-driven immunotherapy research

The University of Pittsburgh's Natasa Miskov-Zivanov, assistant professor of electrical and computer engineering, has received a prestigious Faculty Early Career Development (CAREER) Award of $581,503 from the National Science Foundation (NSF) for her project titled "Artificial Intelligence-Driven Framework for Efficient and Explainable Immunotherapy Design."

30 May 2025

New electrochemical device advances point-of-care HIV diagnostics

Accurate monitoring of CD4+ T cell counts is vital for evaluating immune health and guiding treatment in people living with Human Immunodeficiency Virus (HIV).

30 May 2025

Out-of-hospital cardiac arrest survival drops during COVID-19 with racial disparities

Survival rates for out-of-hospital cardiac arrest (OHCA) fell during the early years of the COVID-19 pandemic, with Black and Hispanic patients experiencing larger decreases in survival, according to a study led by UT Southwestern Medical Center researchers published in Resuscitation.

30 May 2025

LUCAS technology revolutionizes rapid viral diagnostics

Mass General Brigham researchers are shining a powerful new light into the viral darkness with the development of Luminescence CAscade-based Sensor (LUCAS), a rapid, portable, highly-sensitive diagnostic tool for processing complex biological samples.

30 May 2025

TTF1 identified as key biomarker for advanced KRAS G12C-mutated non-small cell lung cancer

Researchers from The University of Texas MD Anderson Cancer Center have identified a new biomarker, TTF-1, that was predictive of survival outcomes for patients with advanced KRAS G12C-mutated non-small cell lung cancer (NSCLC), following treatment with the KRAS targeted therapy sotorasib.

30 May 2025

What drives insulin resistance? Proteomics reveals key pathways in human skeletal muscle

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes therapies based on molecular profiles.

30 May 2025

New insights into decades-old bladder cancer treatment offers clues for immunotherapy

More than three decades ago, the U.S. Food and Drug Administration (FDA) approved Bacillus Calmette-Guérin (BCG) as the first immunotherapy against cancer. And it is still used today to treat early-stage bladder cancer.

29 May 2025

Midlife weight loss may lower your long-term risk of diabetes, study finds

This study shows that midlife weight loss, without medical interventions, reduces chronic disease risk and supports longevity, beyond diabetes benefits.

29 May 2025

Study highlights scholastic needs of adolescents and young adults with cancer

Young patients with cancer need support when it comes to scholastic performance, which can be an empowering and motivating force during the challenges of cancer treatment, UF Health Cancer Center researchers have found.

29 May 2025

Researchers report a new avenue for targeted drug delivery

A new avenue for targeted drug delivery has been proposed by researchers from The Grainger College of Engineering at the University of Illinois Urbana-Champaign.

29 May 2025

Study: General service in the US military may lower the risk of depression

General service in the US military may lower, rather than heighten, the risk of depression, despite the relatively high prevalence of the condition among active duty and veteran personnel, finds a large observational study published online in BMJ Military Health.

29 May 2025

Choosing better carbs in low-carb diets boosts health outcomes

A long-term study of the Framingham Heart Study Offspring cohort found that low-carbohydrate diets emphasizing high-quality carbs, like whole grains, fruits, and vegetables, were linked to reduced inflammation and oxidative stress. Diets low in carbohydrate quality offered no such benefits.

29 May 2025