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ICU risk scores can be repurposed as continuous markers of illness severity

Commonly used ICU risk scores can be "repurposed" as continuous markers of severity of illness in critically ill patients--providing ongoing updates on changes in the patient's condition and risk of death, according to a study in the March issue of Critical Care Medicine, official journal of the Society of Critical Care Medicine. The journal is published by Wolters Kluwer.

27 Feb 2018

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Celgene Corporation today announced that it has received a Refusal to File letter from the United States Food and Drug Administration regarding its New Drug Application for ozanimod in development for the treatment of patients with relapsing forms of multiple sclerosis.

27 Feb 2018

Carnegie Mellon to help develop novel camera that peers deep beneath the skin

Carnegie Mellon University is part of a five-year, $10 million program sponsored by the National Science Foundation to develop a new type of camera that peers deep beneath the skin to help diagnose and monitor a wide variety of health conditions.

27 Feb 2018

Researchers create models that predict spread of flu in the United States

Using several large datasets describing health care visits, geographic movements and demographics of more than 150 million people over nine years, researchers at the University of Chicago have created models that predict the spread of influenza throughout the United States each year.

27 Feb 2018

New guidelines aim to improve quality of high altitude medicine

The aim of these guidelines is to standardize data capture in this area of research and thereby guarantee and indeed improve the quality of clinical research. Scientists from Eurac Research led the evaluation and coordinated the group of experts.

27 Feb 2018

Expanded model of care could relieve depression and fatigue in chronic heart failure patients

Patients with chronic heart failure face related problems, such as depression and fatigue, that could be relieved by an expanded model of care, according to a recently published study led by a researcher from the University of Colorado School of Medicine.

27 Feb 2018

New treatment shows promise to fight against serious inflammatory disease

Still's disease is a serious orphan disease manifested by high fevers, skin and joint involvement, including paralysis, as well as damage to other organs such as the liver or spleen. It is caused by a deregulation of the immune system triggering an acute inflammatory response.

27 Feb 2018

Survival of cardiac arrest victims improves when bystanders use AED shock therapy

Survival from cardiac arrest doubled when a bystander stepped in to apply an automated external defibrillator (AED) before emergency responders arrived, according to new research in the American Heart Association's journal Circulation.

27 Feb 2018

Artificial intelligence methods used for developing precision cancer medicine

A patient's own molecular data can be used to identify, with the use of artificial intelligence methods, the best combinatorial multi-drug therapy for that patient. Network modelling plays a major role in this line of work.

27 Feb 2018

Study finds no relationship between hormonal birth control and depression

A new study has found no connection between hormonal birth control and depression, drawing on data related to several contraception methods, including implants, pills and injections.

27 Feb 2018

Study suggests novel approach for protecting diabetes patients from vascular disease

Recent findings suggest a novel approach for protecting people with diabetes from their higher risk of advanced blood vessel disease, which sets the stage for early heart attacks and strokes.

27 Feb 2018

New military vehicle shock absorbing device may protect troops from blast-induced TBI

Researchers from theUniversity of Maryland School of Medicine and the University of Maryland A. James Clark School of Engineering have developed a new military vehicle shock absorbing device that may protect troops from traumatic brain injury (TBI) after a land mine blast.

27 Feb 2018

Research reveals how mutant p53 enhances tumor metastasis

Scientists at The Wistar Institute have found a novel mechanism through which mutant p53 enhances metastasis by controlling tumor metabolism. The research, published online in Genes & Development, also revealed how this process is influenced by a naturally occurring p53 gene variant.

26 Feb 2018

University of Illinois at Chicago awarded $4.6 million NIH grant for chronic pain research

The University of Illinois at Chicago has been awarded a $4.6 million grant from the National Heart, Lung, and Blood Institute to study the molecular neurobiology of chronic pain in patients with sickle cell disease and to develop potential new drug treatments.

26 Feb 2018

New discovery may allow doctors to treat inflammation in neurodegenerative diseases

A new discovery about the immune system may allow doctors to treat harmful inflammation that damages the brain in neurodegenerative diseases such as Alzheimer's. It might also let doctors save patients from the potentially deadly inflammation of sepsis, a full-body infection that kills a quarter-million Americans every year.

26 Feb 2018

Vitamin D cannot be metabolized without sufficient magnesium levels, review finds

There is a caveat to the push for increased Vitamin D: Don't forget magnesium. A review published in The Journal of the American Osteopathic Association found Vitamin D can't be metabolized without sufficient magnesium levels, meaning Vitamin D remains stored and inactive for as many as 50 percent of Americans.

26 Feb 2018

Lacto-ovo-vegetarian and Mediterranean diets appear to be equally effective in reducing heart disease risk

A lacto-ovo-vegetarian diet, which includes eggs and dairy but excludes meat and fish, and a Mediterranean diet are likely equally effective in reducing the risk of heart disease and stroke, according to new research in the American Heart Association's journal Circulation.

26 Feb 2018

Researchers find no evidence to support link between hormonal birth control and depression

Women face several options when it comes to birth control, so potential side effects often factor into their decision. Depression is a common concern for many women, but a new study by researchers at The Ohio State University Wexner Medical Center is putting patients at ease. It found there's no evidence to support a link between hormonal birth control and depression.

26 Feb 2018

Researchers discover key inner control mechanism of cell's 'smart glue'

Researchers at St. Jude Children's Research Hospital have discovered that a protein critical to a process called liquid-liquid phase separation within the cell undergoes internal changes in conformation that are key to its function.

26 Feb 2018

Research reveals anti-cancer effects of natural extract from Daffodils

A research describes the anti-cancer effects of a natural alkaloid extracted from Daffodils. Led by Denis Lafontaine, affiliated with the Faculty of Sciences at the ULB, the researchers have discovered that this compound triggers the activation of an anti-tumoral surveillance pathway.

26 Feb 2018

Medicine News and Research

ICU risk scores can be repurposed as continuous markers of illness severity

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Carnegie Mellon to help develop novel camera that peers deep beneath the skin

Researchers create models that predict spread of flu in the United States

New guidelines aim to improve quality of high altitude medicine

Expanded model of care could relieve depression and fatigue in chronic heart failure patients

New treatment shows promise to fight against serious inflammatory disease

Survival of cardiac arrest victims improves when bystanders use AED shock therapy

Artificial intelligence methods used for developing precision cancer medicine

Study finds no relationship between hormonal birth control and depression

Study suggests novel approach for protecting diabetes patients from vascular disease

New military vehicle shock absorbing device may protect troops from blast-induced TBI

Research reveals how mutant p53 enhances tumor metastasis

University of Illinois at Chicago awarded $4.6 million NIH grant for chronic pain research

New discovery may allow doctors to treat inflammation in neurodegenerative diseases

Vitamin D cannot be metabolized without sufficient magnesium levels, review finds

Lacto-ovo-vegetarian and Mediterranean diets appear to be equally effective in reducing heart disease risk

Researchers find no evidence to support link between hormonal birth control and depression

Researchers discover key inner control mechanism of cell's 'smart glue'

Research reveals anti-cancer effects of natural extract from Daffodils

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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