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Finding suggests that retina acts as type of window to the brain

Researchers at the Gladstone Institutes and University of California, San Francisco have shown that a loss of cells in the retina is one of the earliest signs of frontotemporal dementia (FTD) in people with a genetic risk for the disorder-even before any changes appear in their behavior.

25 Aug 2014

Statistical genetic analysis can detect aggressiveness of lymphoma

Each year, more than one thousand Norwegians develop lymphoma. A statistical genetic analysis can detect when the disease will be aggressive. Thereby, treatment can be initiated in time.

25 Aug 2014

Researchers examine impact of BIM deletion on survival outcomes of advanced NSCLC patients

Bcl-2-like protein 11 (BIM) deletion in advanced non-small cell lung cancer (NSCLC) is associated with shorter progression free survival (PFS) in epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) or chemotherapy treated Asian patients.

25 Aug 2014

Clinical study shows long-term effectiveness of Orthocell’s Ortho-ATI™ for treatment resistant tennis elbow

Regenerative medicine company Orthocell Limited has today released results from a long-term clinical study into its Ortho-ATI™ treatment for tennis elbow that provides evidence of the durability and long term success of this treatment.

25 Aug 2014

Study finds a host of new clues on gene-environment interactions in Crohn's disease

A new study finds a wide range of epigenetic changes-alterations in DNA across the genome that may be related to key environmental exposures-in children with Crohn's disease (CD), reports Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America.

23 Aug 2014

SeraCare Life Sciences announces launch of new ACCURUN 501 C. difficile Control

SeraCare Life Sciences, a provider of high-quality biological materials that help optimize diagnostic performance, reliability and repeatability across the IVD lifecycle, today announced the launch of its new ACCURUN 501 C. difficile Control – the company's first molecular control product targeting hospital acquired infections.

23 Aug 2014

FDA approves ViiV Healthcare's Triumeq tablets for treatment of HIV-1 infection

ViiV Healthcare announced today that the US Food and Drug Administration has approved Triumeq (abacavir 600mg, dolutegravir 50mg and lamivudine 300mg) tablets for the treatment of HIV-1 infection.

23 Aug 2014

New mouse model to open door to research on epilepsy, Alzheimer's

University of Utah scientists have developed a genetically engineered line of mice that is expected to open the door to new research on epilepsy, Alzheimer's and other diseases.

22 Aug 2014

Understanding neuron development: an interview with Dr. Brock Grill, The Scripps Research Institute

There’s a big difference between understanding coordination and actually building connectivity. In terms of building connectivity, several molecules have been identified that control this process and a lot has been learned from both genetic and biochemical research in a variety of different systems, particularly studies in the nematode C. elegans, the fruit fly Drosophila and mice.

22 Aug 2014

Race and ethnicity influence outcomes of patients with motor complete SCI

Researchers have published a study examining racial and ethnic influences in the outcomes of patients with motor complete spinal cord injury (SCI). The article, "Racial and ethnic disparities in functioning at discharge and follow-up among patients with motor complete SCI," was published online ahead of print on August 2 by the Archives of Physical Medicine & Rehabilitation.

22 Aug 2014

Three commonly used NSAIDs affect cell membranes, produce unwanted side effects

Researchers have discovered that three commonly used nonsteroidal anti-inflammatory drugs, or NSAIDs, alter the activity of enzymes within cell membranes. Their finding suggests that, if taken at higher-than-approved doses and/or for long periods of time, these prescription-level NSAIDs and other drugs that affect the membrane may produce wide-ranging and unwanted side effects.

22 Aug 2014

ESMO announces names of outstanding individuals receiving annual awards

The European Society for Medical Oncology, the leading pan-European organisation representing medical oncologists, announced the names of outstanding individuals receiving the Society's esteemed annual awards, to be presented during the ESMO 2014 Congress, on 26 September, in Madrid.

22 Aug 2014

Sen. Pryor debuts campaign ad embracing health law provisions

The Arkansas Democrat, who is in a tough reelection fight, talked about his own struggle with cancer and how the health law provisions that prohibit insurance companies from denying coverage to people with medical problems could have helped him.

22 Aug 2014

Study shows new role for protein APC in suppressing colorectal cancer

A study recently published in the journal Carcinogenesis by researchers at the University of Kansas shows a new role for the protein adenomatous polyposis coli (APC) in suppressing colorectal cancer - the second-leading cause of cancer-related deaths in the U.S.

22 Aug 2014

Lilly’s ixekizumab superior to placebo, etanercept on all skin clearance measures in Phase 3 studies

Eli Lilly and Company's investigational medicine ixekizumab was statistically superior to etanercept and placebo on all skin clearance measures in Phase 3 studies, the company said today in disclosing top-line results from its pivotal UNCOVER studies in moderate-to-severe plaque psoriasis.

22 Aug 2014

Penn Medicine launches CAROT to build novel therapies for retinal and ocular disorders

The Perelman School of Medicine at the University of Pennsylvania has launched the Penn Center for Advanced Retinal and Ocular Therapeutics (CAROT) to build on its previous success developing novel therapies for the personalized diagnosis and treatment of retinal and ocular disorders.

22 Aug 2014

DNA testing for congenital cataracts can accurately diagnose diseases linked to childhood blindness

Researchers in the United Kingdom have demonstrated that advanced DNA testing for congenital cataracts can quickly and accurately diagnose a number of rare diseases marked by childhood blindness, according to a study published online today in Ophthalmology, the journal of the American Academy of Ophthalmology.

22 Aug 2014

Allen Institute for Brain Science welcomes visiting scientist engineer

The Allen Institute for Brain Science welcomes a visiting scientist from Harvard and a visiting engineer from Georgia Tech: Sharad Ramanathan, Ph.D.; and Craig Forest, Ph.D. Both Ramanathan and Forest will bring their distinct knowledge and backgrounds to the expanding scientific teams at the Allen Institute.

22 Aug 2014

NeuroDerm signs definitive investment agreements for $16 million financing round

NeuroDerm Ltd., a clinical stage pharmaceutical company developing drugs for central nervous system (CNS) diseases, today announced that it has signed definitive investment agreements for a $16 million financing round led by certain of its existing investors with the participation of new investors, including The Elias Group.

21 Aug 2014

Pre-op PET/CT predicts stage I NSCLC adjuvant chemotherapy benefit

Preoperative imaging could help guide the use of postoperative adjuvant chemotherapy in patients with early non-small-cell lung cancer, Japanese researchers believe.

21 Aug 2014

Cell News and Research

Finding suggests that retina acts as type of window to the brain

Statistical genetic analysis can detect aggressiveness of lymphoma

Researchers examine impact of BIM deletion on survival outcomes of advanced NSCLC patients

Clinical study shows long-term effectiveness of Orthocell’s Ortho-ATI™ for treatment resistant tennis elbow

Study finds a host of new clues on gene-environment interactions in Crohn's disease

SeraCare Life Sciences announces launch of new ACCURUN 501 C. difficile Control

FDA approves ViiV Healthcare's Triumeq tablets for treatment of HIV-1 infection

New mouse model to open door to research on epilepsy, Alzheimer's

Understanding neuron development: an interview with Dr. Brock Grill, The Scripps Research Institute

Race and ethnicity influence outcomes of patients with motor complete SCI

Three commonly used NSAIDs affect cell membranes, produce unwanted side effects

ESMO announces names of outstanding individuals receiving annual awards

Sen. Pryor debuts campaign ad embracing health law provisions

Study shows new role for protein APC in suppressing colorectal cancer

Lilly’s ixekizumab superior to placebo, etanercept on all skin clearance measures in Phase 3 studies

Penn Medicine launches CAROT to build novel therapies for retinal and ocular disorders

DNA testing for congenital cataracts can accurately diagnose diseases linked to childhood blindness

Allen Institute for Brain Science welcomes visiting scientist engineer

NeuroDerm signs definitive investment agreements for $16 million financing round

Pre-op PET/CT predicts stage I NSCLC adjuvant chemotherapy benefit

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