Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Research: Underweight puts people at highest risk of dying, just as obesity does

Being underweight puts people at highest risk of dying, just as obesity does, new research has found. The connection between being underweight and the higher risk of dying is true for both adults and fetuses.

29 Mar 2014

Takeda to present results from global EXAMINE CV safety outcomes trial at ACC 2014

Takeda Pharmaceuticals Company Limited will present sub-analyses from the global EXAMINE (EXamination of CArdiovascular OutcoMes: AlogliptIN vs. Standard of CarE in Patients with Type 2 Diabetes Mellitus and Acute Coronary Syndrome) cardiovascular (CV) safety outcomes trial in a poster session at the American College of Cardiology’s 63rd Annual Scientific Session in Washington, DC.

28 Mar 2014

Formula for peak exercise heart rate does not account for differences between men and women

The formula for peak exercise heart rate that doctors have used for decades in tests to diagnose heart conditions may be flawed because it does not account for differences between men and women, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Heart failure patients benefit from new device till transplant

The largest single-center study of patients implanted with a total artificial heart finds the device may help patients in severe heart failure survive until they can receive a heart transplant, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Study links broken heart syndrome to natural disasters

Dramatic spikes in cases of Takotsubo cardiomyopathy, also called broken heart syndrome, were found in two states after major natural disasters, suggesting the stress of disasters as a likely trigger, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

28 Mar 2014

Cardiovascular disease related deaths drop after implementation of public smoking ban

A new study on the impact of Michigan's statewide smoking ban adds to mounting evidence that policies prohibiting tobacco smoking in workplaces and other public spaces may substantially improve public health by reducing heart disease and death, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

27 Mar 2014

Study: Depression treatments reduce mortality in patients with cardiovascular disease

Can treating depression in patients with heart failure help them live longer? That's one of the questions that University of Pittsburgh researchers hope to answer with a new five-year, $7.3 million grant from the National Heart, Lung, and Blood Institute, part of the National Institutes of Health (NIH).

27 Mar 2014

Expert highlights the importance of gender-specific approach for treating diabetes mellitus

The international guidelines on the drug-based therapy of diabetes mellitus specify which factors need to be taken into account during treatment.

27 Mar 2014

Mast Therapeutics reports net loss of $5.7 million for fourth quarter 2013

Mast Therapeutics, Inc. today reported financial results for the fourth quarter and year ended December 31, 2013.

26 Mar 2014

ZS Pharma starts patient enrollment in ZS-9 Phase 3 trial for treatment of hyperkalemia

ZS Pharma, a specialty pharmaceutical company developing novel treatments for kidney, cardiovascular and liver disorders, today announced that it has begun enrolling patients in ZS004, its second Phase 3 clinical trial of ZS-9, a novel investigational treatment for hyperkalemia.

25 Mar 2014

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

A protein known to promote cancer appears to give the blood vessels strength and shape, researchers report. When yes-associated protein, or YAP, is deleted from vascular smooth muscle cells during development, the protein makes thin-walled blood vessels that over-dilate in response to the usual pressure of blood flow, said Dr. Jiliang Zhou, vascular biologist at the Medical College of Georgia at Georgia Regents University.

25 Mar 2014

‘Residual risk’ concern for treated Japanese hypertension patients

Physicians should be alert to other sources of cardiovascular risk in patients with hypertension, even if they are receiving optimal antihypertensive treatment, say Japanese researchers.

24 Mar 2014

FDA approves Allure Quadra Cardiac Resynchronization Therapy Pacemaker

St. Jude Medical, Inc., a global medical device company, today announced approval from the U.S. Food and Drug Administration (FDA) for the Allure Quadra™ Cardiac Resynchronization Therapy Pacemaker (CRT-P), which provides additional pacing innovations for physicians to treat patients with heart failure.

24 Mar 2014

GHIT Fund announces grants to speed up innovative drug development for neglected diseases

The Global Health Innovative Technology Fund, a new public health partnership that is bringing Japanese know-how and investment to the global fight against infectious diseases, today announced three grants worth a total of US$6.8 million to speed the development of innovative drugs for some of the world’s most neglected diseases—schistosomiasis, Chagas disease and parasitic roundworms.

20 Mar 2014

Consuming alcohol several times a week 'ups' risk of stroke mortality

Consuming alcohol more frequently than twice a week increases the risk of stroke mortality in men, according to a study carried out at the University of Eastern Finland. The results show that the effects of alcohol are not limited to the amount consumed, but also the frequency of drinking matters. The results were published in Acta Neurologica Scandinavica on 8 March.

19 Mar 2014

Study: Daily dietary supplements not associated with reduced risk for CVD in elderly

Daily dietary supplements of omega-3 polyunsaturated fatty acids (also found in fish) or lutein and zeaxanthin (nutrients found in green leafy vegetables) were not associated with reduced risk for cardiovascular disease (CVD) in elderly patients with the eye disease age-related macular degeneration.

19 Mar 2014

Shortness of breath while bending over is a new heart failure symptom

UT Southwestern Medical Center cardiologists have defined a novel heart failure symptom in advanced heart failure patients: shortness of breath while bending over, such as when putting on shoes.

19 Mar 2014

Amgen announces results from Phase 3 TESLA Trial of evolocumab in patients with HoFH

Amgen (NASDAQ: AMGN) today announced that the Phase 3 TESLA (Trial Evaluating PCSK9 Antibody in Subjects with LDL Receptor Abnormalities) trial evaluating evolocumab met its primary endpoint of the percent reduction from baseline at week 12 in low-density lipoprotein cholesterol (LDL-C).

19 Mar 2014

Cardiac arrest during childbirth may be 2 times more common than previously reported

Although cardiac arrest during childbirth is rare, it may be two times more common than previously reported in the literature, suggests the first large U.S. study on the potentially deadly condition published in the April issue of Anesthesiology.

19 Mar 2014

Lung ultrasound could help determine if pregnant woman with preeclampsia is at risk for respiratory failure

18 Mar 2014

Heart Failure News and Research

Further Reading

Research: Underweight puts people at highest risk of dying, just as obesity does

Takeda to present results from global EXAMINE CV safety outcomes trial at ACC 2014

Formula for peak exercise heart rate does not account for differences between men and women

Heart failure patients benefit from new device till transplant

Study links broken heart syndrome to natural disasters

Cardiovascular disease related deaths drop after implementation of public smoking ban

Study: Depression treatments reduce mortality in patients with cardiovascular disease

Expert highlights the importance of gender-specific approach for treating diabetes mellitus

Mast Therapeutics reports net loss of $5.7 million for fourth quarter 2013

ZS Pharma starts patient enrollment in ZS-9 Phase 3 trial for treatment of hyperkalemia

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

‘Residual risk’ concern for treated Japanese hypertension patients

FDA approves Allure Quadra Cardiac Resynchronization Therapy Pacemaker

GHIT Fund announces grants to speed up innovative drug development for neglected diseases

Consuming alcohol several times a week 'ups' risk of stroke mortality

Study: Daily dietary supplements not associated with reduced risk for CVD in elderly

Shortness of breath while bending over is a new heart failure symptom

Amgen announces results from Phase 3 TESLA Trial of evolocumab in patients with HoFH

Cardiac arrest during childbirth may be 2 times more common than previously reported

Lung ultrasound could help determine if pregnant woman with preeclampsia is at risk for respiratory failure

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Bringing real-time analytics to downstream bioprocess monitoring

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Evaluating new approaches for rare disease genomics

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