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Experts at ABTA conference reveal possible causes, risk factors for brain tumors

Today, nearly 700,000 people in the U.S. are living with a brain tumor, and yet, when it comes to pinpointing causes or risk factors, scientists are still searching for answers.

25 Jul 2014

Genticel provides update on patents granted in the USA and Asia

Genticel, a French biotechnology company and leading developer of therapeutic vaccines, provides an update on patents that have recently enriched its intellectual property estate.

25 Jul 2014

Autophagy prevents accumulation of toxic proteins associated with type 2 diabetes

People with Type 2 diabetes have an excess of a protein called islet amyloid polypeptide, or IAPP, and the accumulation of this protein is linked to the loss of insulin-producing pancreatic beta cells.

25 Jul 2014

CCC study provides hope that SapC-DOPS could be used for metastatic brain cancer treatment

Over half of patients being seen in the clinic for a diagnosed brain tumor have metastatic cancer, which has no treatment and detrimental outcomes in most cases.

25 Jul 2014

Study identifies molecular mechanisms could lead to new therapies to treat obesity, diabetes

A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, UT Southwestern Medical Center researchers have found.

25 Jul 2014

UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

Millions of people in the United States have a circulatory problem of the legs called peripheral vascular disease. It can be painful and may even require surgery in serious cases. This disease can lead to severe skeletal muscle wasting and, in turn, limb amputation.

25 Jul 2014

Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Bayer HealthCare and Onyx Pharmaceuticals Inc., an Amgen subsidiary, today announced that an investigational Phase 3 trial of NEXAVAR (sorafenib) tablets in patients with advanced breast cancer did not meet its primary endpoint of improving progression-free survival (PFS).

25 Jul 2014

Immunologic mechanism makes broadly neutralizing antibodies in people infected with HIV

Scientists at Duke Medicine have found an immunologic mechanism that makes broadly neutralizing antibodies in people who are HIV-1 infected.

25 Jul 2014

Researchers recommend low carbohydrate diet for Type 1 and Type 2 diabetes

A new study involving researchers from the University of Alabama at Birmingham and other institutions says patients with Type 1 and Type 2 diabetes should eat a diet low in carbohydrates.

25 Jul 2014

Discovery could lead to novel drugs to tackle melanoma

Skin Cancer cells work together to spread further and faster, according to a new study published in Cell Reports. The discovery could lead to new drugs to tackle melanoma, the most deadly form of skin cancer.

25 Jul 2014

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers at UC San Francisco (UCSF) have discovered that endostatin, a protein that once aroused intense interest as a possible cancer treatment, plays a key role in the stable functioning of the nervous system.

25 Jul 2014

Researchers working to develop new drugs for treating chronic inflammatory diseases

Science and industry are collaborating to develop future pharmaceuticals for treating chronic inflammatory diseases. The medicines will combat immunological processes that have gone wrong.

25 Jul 2014

Clinical study aims to validate preventive treatment against tumor metastasis

Metastasis, the strategy adopted by tumor cells to transform into an aggressive form of cancer, are often associated with a gloomy prognosis. Managing to block the metastasis or, even better, prevent their formation would be a giant step towards the fight against cancer.

25 Jul 2014

Scientists one step closer to creating viable cell replacement therapy for multiple sclerosis patients

Scientists at The New York Stem Cell Foundation Research Institute are one step closer to creating a viable cell replacement therapy for multiple sclerosis from a patient's own cells.

25 Jul 2014

Kinex receives FDA approval to begin Phase I study of KX2-391 Ointment for actinic keratosis

Kinex Pharmaceuticals announced the receipt of an allowance by the US FDA for the Company's KX2-391 Ointment for the commencement of a Phase I clinical study in actinic keratosis. This is the Company's third IND to be allowed by the US FDA in the past 12 months.

25 Jul 2014

Compounds developed for cancer treatment show promise as potential oral therapy for Alzheimer's

Currently, no cure exists for Alzheimer's disease, the devastating neurological disease affecting more than 5 million Americans. But scientists are now reporting new progress on a set of compounds, initially developed for cancer treatment, that shows promise as a potential oral therapy for Alzheimer's. Their study appears in ACS' Journal of Medicinal Chemistry.

24 Jul 2014

Clinic-based audio project gives HIV patients a chance to share experiences with diagnosis

The voice on the recording was low and calm as the speaker recounted the telephone call that brought the news he was infected with the human immunodeficiency virus (HIV) that causes AIDS: "My heart just stopped for a little bit and next thing you know I was on the floor flat on my face boohooing, crying like a baby."

24 Jul 2014

Study identifies three genetic changes linked to increased risk of breast cancer in East Asian women

A new study in East Asian women has identified three genetic changes linked to an increased risk of breast cancer. The research, led by Vanderbilt University investigators, was published online July 20 in Nature Genetics.

24 Jul 2014

NYSCF and Beyond Batten Disease Foundation partner to find cure for juvenile Batten disease

The New York Stem Cell Foundation (NYSCF) and Beyond Batten Disease Foundation (BBDF) have partnered to develop stem cell resources to investigate and explore new treatments and ultimately find a cure for juvenile Batten disease, a fatal illness affecting children.

24 Jul 2014

Capsazepine shows dramatic tumor shrinkage without damaging surrounding tissues

Mouse models of human oral cancer treated with an agent called capsazepine showed dramatic tumor shrinkage without damage to surrounding tissues, researchers from the School of Dentistry and School of Medicine at The University of Texas Health Science Center at San Antonio found.

24 Jul 2014

Cell News and Research

Experts at ABTA conference reveal possible causes, risk factors for brain tumors

Genticel provides update on patents granted in the USA and Asia

Autophagy prevents accumulation of toxic proteins associated with type 2 diabetes

CCC study provides hope that SapC-DOPS could be used for metastatic brain cancer treatment

Study identifies molecular mechanisms could lead to new therapies to treat obesity, diabetes

UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Immunologic mechanism makes broadly neutralizing antibodies in people infected with HIV

Researchers recommend low carbohydrate diet for Type 1 and Type 2 diabetes

Discovery could lead to novel drugs to tackle melanoma

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers working to develop new drugs for treating chronic inflammatory diseases

Clinical study aims to validate preventive treatment against tumor metastasis

Scientists one step closer to creating viable cell replacement therapy for multiple sclerosis patients

Kinex receives FDA approval to begin Phase I study of KX2-391 Ointment for actinic keratosis

Compounds developed for cancer treatment show promise as potential oral therapy for Alzheimer's

Clinic-based audio project gives HIV patients a chance to share experiences with diagnosis

Study identifies three genetic changes linked to increased risk of breast cancer in East Asian women

NYSCF and Beyond Batten Disease Foundation partner to find cure for juvenile Batten disease

Capsazepine shows dramatic tumor shrinkage without damaging surrounding tissues

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