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IGF-axis proteins may have a role in development of type 2 diabetes

Researchers at Albert Einstein College of Medicine of Yeshiva University in collaboration with Nurses' Health Study investigators have shown that levels of certain related proteins found in blood are associated with a greatly reduced risk for developing type 2 diabetes up to a decade or more later. The findings, published today in the online edition of Diabetes, could open a new front in the war against diabetes.

4 May 2012

Scientists discover new type of dynamic change in human stem cells

A team led by scientists at The Scripps Research Institute and the University of California (UC) San Diego has discovered a new type of dynamic change in human stem cells.

4 May 2012

Hypoxia may be a primary cause of uncontrollable tumor growth in cancers

Low oxygen levels in cells may be a primary cause of uncontrollable tumor growth in some cancers, according to a new University of Georgia study. The authors' findings run counter to widely accepted beliefs that genetic mutations are responsible for cancer growth.

4 May 2012

Scientists discover key element in DNA repair mechanism

Scientists from the Kavli Institute of Nanoscience at Delft University of Technology have discovered a key element in the mechanism of DNA repair.

4 May 2012

CAPE arrests growth of prostate cancer cells and tumors in mice

An over-the-counter natural remedy derived from honeybee hives arrests the growth of prostate cancer cells and tumors in mice, according to a new paper from researchers at the University of Chicago Medicine.

4 May 2012

Affymetrix to acquire eBioscience

Affymetrix, Inc., and eBioscience, Inc., a privately-held San Diego, CA-based company with an industry-leading position in flow cytometry and immunoassay reagents for immunology and oncology research and diagnostics, today announced they have amended their existing definitive agreement dated November 29, 2011 under which Affymetrix will acquire eBioscience.

4 May 2012

Scientists identify first gene associated with congenital asplenia

Researchers at Weill Cornell Medical College and Rockefeller University have identified the first gene to be linked to a rare condition in which babies are born without a spleen, putting those children at risk of dying from infections they cannot defend themselves against. The gene, Nkx2.5, was shown to regulate genesis of the spleen during early development in mice.

4 May 2012

Metagenics launches NutraGems CoQ10 300 to support cardiovascular health

Metagenics, Inc., a nutrigenomics and lifestyle medicine company focused on improving health, announced today the launch of NutraGems CoQ10 300.

4 May 2012

State of health, not age, should decide treatment for cancer

In a study of patients 65 and older with non-small-cell lung cancer (NSCLC), younger patients were more likely to receive treatment than older patients, regardless of overall health and prognosis.

3 May 2012

A test to predict breast cancer many years before the disease is diagnosed

Ultimately the findings, in the journal Cancer Research, could lead to a simple blood test to screen women, they say. The test looks for how genes are altered by environmental factors like alcohol and hormones - a process known as epigenetics. One in five women is thought to have such a genetic “switch” that doubles breast cancer risk say researchers.

3 May 2012

Large-scale, patient-specific simulations of blood function

Having a virtual copy of a patient's blood in a computer would be a boon to researchers and doctors. They could examine a simulated heart attack caused by blood clotting in a diseased coronary artery and see if a drug like aspirin would be effective in reducing the size of such a clot.

3 May 2012

Symposium at EuroPRevent 2012 highlights benefits of oily fish consumption

Most people, whether healthy or having cardiovascular disease (CVD), would benefit from regular consumption of oily fish, concluded speakers at the EuroPRevent 2012 meeting. While eating whole fish undoubtedly offers the optimum approach for increasing omega-3 intakes in both primary and secondary prevention, delegates heard, supplements have a major role to play in increasing omega-3 intakes for people who do not like fish.

3 May 2012

Novel stem cell transplantation holds promise for HIV prevention

UC Davis Health System researchers are a step closer to launching human clinical trials involving the use of an innovative stem cell therapy to fight the virus that causes AIDS.

3 May 2012

New clues about why immune system fails to kill tumors in mice

A pioneering approach to imaging breast cancer in mice has revealed new clues about why the human immune system often fails to attack tumors and keep cancer in check. This observation, by scientists at the University of California, San Francisco (UCSF), may help to reveal new approaches to cancer immunotherapy.

3 May 2012

NJIT professor receives $340,000 NIH grant to investigate membrane proteins

NJIT Associate Professor Edgardo Farinas has been awarded today a three-year $340,000 National Institutes of Health (NIH) grant to investigate spores as a protein display platform for the directed evolution of membrane proteins.

3 May 2012

Viewpoints: The health law's double count on Medicare funding; Pa. budget endangering health safety net; A doctor's call for more texting

One of the enduring mysteries of President Obama's health law is how its spending constraints and payroll tax hikes on high earners can be used to shore up Medicare finances and at the same time pay for a massive new entitlement program. Isn't this double counting?

3 May 2012

Elsevier, AAGP partner to publish American Journal of Geriatric Psychiatry

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announces that it has entered into an agreement with the American Association for Geriatric Psychiatry (AAGP) to publish The American Journal of Geriatric Psychiatry (AJGP) beginning in January 2013.

3 May 2012

Math models can be useful tools for study of cancer progression

Using mathematical models, researchers in the Integrated Mathematical Oncology (IMO) program at Moffitt Cancer Center are focusing their research on the interaction between the tumor and its microenvironment and the "selective forces" in that microenvironment that play a role in the growth and evolution of cancer.

3 May 2012

Study investigates use of stem cells to treat lower-limb peripheral artery disease

Research led by vascular surgeons at Dartmouth-Hitchcock may offer new hope to sufferers of peripheral artery disease, the cause of nearly 60,000 lower-limb amputations annually, through the use of a patient's own stem cells.

3 May 2012

German BfArM grants Moberg Derma approval to initiate Limtop phase II actinic keratosis trial

The German Federal Institute for Drugs and Medical Devices (BfArM) has granted Moberg Derma approval to initiate a clinical phase II trial for Limtop. The aim is to evaluate the efficacy and safety of three different dose regimens of Limtop in a study involving 96 patients with Actinic Keratosis (AK) on the head or face.

2 May 2012