Cell News and Research

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Cell Therapeutics announces launch of PIXUVRI in the UK for treatment of aggressive B-cell NHL

Cell Therapeutics, Inc. today announced the launch of PIXUVRI (pixantrone), the first new treatment for adult patients in the United Kingdom (UK) with multiply relapsed or refractory aggressive B-cell non-Hodgkin lymphoma (aggressive B-cell NHL), at the 54th annual scientific meeting of the British Society for Haematology.

29 Apr 2014

Single cell type actively suppressed in several experimental cancer vaccines

Most cancer vaccines have not lived up to their promise in clinical trials. The reason, many researchers suspect, is that the immune cells that would help the body destroy the tumor - even those reactions boosted by cancer vaccines - are actively suppressed.

29 Apr 2014

BRCA gene loss may accelerate cancer-promoting chromosome rearrangements

Inherited mutations in the BRCA1 or BRCA2 tumor suppressor genes are by far the most frequent contributors to hereditary cancer risk in the human population, often causing breast or ovarian cancer in young women of child-bearing age.

29 Apr 2014

Life stressors may activate neurological disorders

When mothers are exposed to trauma, illness, alcohol or other drug abuse, these stressors may activate a single molecular trigger in brain cells that can go awry and activate conditions such as schizophrenia, post-traumatic stress disorder and some forms of autism.

26 Apr 2014

Skin Cancer Awareness Month and Melanoma Monday: Mount Sinai experts to share vital skin cancer tips

Skin cancer is the most common form of cancer in the United States, with one in five Americans developing it over the course of their lives. It's also one of the most preventable types of cancers. In recognition of May's Skin Cancer Awareness Month and Melanoma Monday on May 5th, Mount Sinai Health System experts are arming the public with vital tips on prevention and offering FREE skin cancer screenings.

26 Apr 2014

European Commission approves VOKANAMET for treatment of adults with type 2 diabetes mellitus

Janssen-Cilag International NV (Janssen) announced today that the European Commission (EC) has approved VOKANAMET® (a fixed-dose therapy combining canagliflozin and immediate release metformin hydrochloride in a single tablet) in the European Union, for the treatment of adults with type 2 diabetes mellitus to improve glycaemic control.

26 Apr 2014

Researchers identify genetic factors that contribute to ADHD in humans

The 60 trillion cells that comprise our bodies communicate constantly. Information travels when chemical compounds released by some cells are received by receptors in the membrane of another cell.

26 Apr 2014

Cells are more resilient than originally thought, say scientists

New research shows that cells are more resilient in taking care of their DNA than scientists originally thought. Even when missing critical components, cells can adapt and make copies of their DNA in an alternative way.

26 Apr 2014

Virginia Tech scientist receives grant to develop technique to detect subcellular location of protein

Virginia Tech chemical engineer Chang Lu and his colleagues have used a National Science Foundation grant to develop a technique to detect subcellular location of a protein.

26 Apr 2014

Researchers use RNA sequencing to look at early- and late-stage development of the heart

Most people think the development of the heart only happens in the womb, however the days and weeks following birth are full of cellular changes that play a role in the structure and function of the heart. Using mouse models, researchers at Baylor College of Medicine have now been able to categorize the alternative splicing (the process in which genes code proteins, determining their role) that takes place during these changes and what mechanisms they affect.

26 Apr 2014

University of Michigan scientists uncover how cells block mutation-causing activity of junk DNA

There's a civil war going on inside every one of the 37 trillion cells in your body. Now, University of Michigan scientists have uncovered how your cells keep this war from causing too much collateral damage.

26 Apr 2014

New data from EMD Serono's multiple sclerosis portfolio to be presented at the 66th AAN Annual Meeting

EMD Serono, Inc., a subsidiary of Merck KGaA, Darmstadt, Germany, announced today that new data from the company's multiple sclerosis (MS) portfolio will be presented at the American Academy of Neurology's 66th Annual Meeting, taking place from April 26 – May 3, in Philadelphia, PA.

26 Apr 2014

Biologists identify how T-type channels change electrochemical signaling of heart and brain cells

Biologists have discovered how an outer shield over T-type channels change the electrochemical signaling of heart and brain cells. Understanding how these shields work will help researchers eventually develop a new class of drugs for treating epilepsy, cardiovascular disease and cancer.

26 Apr 2014

Stem cell production becomes much easier with polymer-based 3D culture system

Mass producing human pluripotent stem cells (hPSCs), including embryonic stem cells and induced pluripotent stem cells, for regenerative medicine and drug discovery may have gotten much easier, thanks to a polymer-based 3D culture system developed by Japanese researchers.

26 Apr 2014

UTMB awarded $6.6 million grant to establish Translational Addiction Sciences Center

The National Institute on Drug Abuse has awarded a five-year, $6.6 million grant to the University of Texas Medical Branch at Galveston to establish the Translational Addiction Sciences Center. The center will investigate the mechanisms underlying addiction with the goal of discovering and validating novel treatment options.

26 Apr 2014

Johns Hopkins research may help manage the disruptive effects experienced by shift workers

Johns Hopkins researchers report that they have identified a protein essential to the formation of the tiny brain region in mice that coordinates sleep-wake cycles and other so-called circadian rhythms.

26 Apr 2014

Study could lead to better understanding of how Notch protein directs healthy development of organs

Johns Hopkins researchers report they have figured out how the aptly named protein Botch blocks the signaling protein called Notch, which helps regulate development. In a report on the discovery, to appear online April 24 in the journal Cell Reports, the scientists say they expect the work to lead to a better understanding of how a single protein, Notch, directs actions needed for the healthy development of organs as diverse as brains and kidneys.

26 Apr 2014

Findings shed light on evolution of mammalian behaviors and their brain mechanisms

A team led by scientists at The Scripps Research Institute has deciphered the surprisingly versatile code by which chemical cues help trigger some of the most basic behaviors in mice.

26 Apr 2014

Methadone safety: New clinical practice guideline from American Pain Society

Improved physician education and patient counseling about methadone safety and ECG monitoring to identify patients at high risk for cardiac problems will lead to safer use of the medication, according to the American Pain Society's Clinical Practice Guideline on Methadone Safety, published this week in The Journal of Pain.

26 Apr 2014

Discovery offers potential target for reversing progression of end-stage liver disease

A team of researchers in the University of Arizona's College of Pharmacy has discovered a molecular pathway that could be key to creating new therapeutics that would slow or even reverse the progression of end-stage liver disease.

26 Apr 2014

Cell News and Research

Cell Therapeutics announces launch of PIXUVRI in the UK for treatment of aggressive B-cell NHL

Single cell type actively suppressed in several experimental cancer vaccines

BRCA gene loss may accelerate cancer-promoting chromosome rearrangements

Life stressors may activate neurological disorders

Skin Cancer Awareness Month and Melanoma Monday: Mount Sinai experts to share vital skin cancer tips

European Commission approves VOKANAMET for treatment of adults with type 2 diabetes mellitus

Researchers identify genetic factors that contribute to ADHD in humans

Cells are more resilient than originally thought, say scientists

Virginia Tech scientist receives grant to develop technique to detect subcellular location of protein

Researchers use RNA sequencing to look at early- and late-stage development of the heart

University of Michigan scientists uncover how cells block mutation-causing activity of junk DNA

New data from EMD Serono's multiple sclerosis portfolio to be presented at the 66th AAN Annual Meeting

Biologists identify how T-type channels change electrochemical signaling of heart and brain cells

Stem cell production becomes much easier with polymer-based 3D culture system

UTMB awarded $6.6 million grant to establish Translational Addiction Sciences Center

Johns Hopkins research may help manage the disruptive effects experienced by shift workers

Study could lead to better understanding of how Notch protein directs healthy development of organs

Findings shed light on evolution of mammalian behaviors and their brain mechanisms

Methadone safety: New clinical practice guideline from American Pain Society

Discovery offers potential target for reversing progression of end-stage liver disease

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