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New study identifies 40 genes susceptible to migraine

Migraine is one of the most common neurological disorders and it affects 1 out of 7 people in the world. Painful and incapacitating, it has multi-factor origins, with the participation of environmental triggering factors and several altered genes in each individual.

23 Jun 2016

Everolimus-eluting bioresorbable vascular scaffold shows promise in PAD

A first-in-human trial of an everolimus-eluting bioresorbable vascular scaffold has shown that the device can achieve a high 2-year patency rate and low 2-year target lesion revascularisation rate in patients with peripheral artery disease involving the external iliac artery and superficial femoral artery.

23 Jun 2016

Researchers identify 38 independent genomic regions linked to migraine

The results of the largest genetic study on migraine thus far were published online in the journal Nature Genetics today, June 20. The study was based on DNA samples of 375,000 European, American and Australian participants. Almost 60,000 of them suffer from migraine.

21 Jun 2016

Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

Gestational diabetes can put babies at a lifelong risk for cardiovascular disease, and scientists want to better understand how.

21 Jun 2016

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

Researchers have identified a new signaling pathway that helps cancer cells cope with the lack of oxygen found inside tumors. These are the results of a study published in Nature Cell Biology on June 20, and led by researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center, Princess Margaret Cancer Center, the University of Toronto, Harvard Medical School and Oxford University.

21 Jun 2016

VentureMed Group receives FDA 510(k) clearance for FLEX Scoring Catheter

VentureMed Group, Ltd., a medical device company based in northwest Ohio, has received 510(k) clearance from the U.S. Food and Drug Administration for the commercial distribution of a new surgical device for treating peripheral artery disease (PAD).

20 Jun 2016

Study finds link between pontosubicular necrosis and placental pathology

Pediatric and Developmental Pathology – A stillbirth occurs when a baby is born without any signs of life. Placental pathology is found to be related to the cause of death in a significant number of pregnancies that result in stillbirth

20 Jun 2016

Cabozantinib extends advanced RCC overall survival

Patients with advanced or metastatic renal cell carcinoma derive a significant overall survival benefit from second-line treatment with the multi-tyrosine kinase inhibitor cabozantinib relative to everolimus.

18 Jun 2016

Worsening renal function linked to increased cardiovascular risk in AF

Patients with atrial fibrillation and declining renal function are at increased risk of subsequent stroke or systemic embolism, major bleeding and death, US researchers report.

17 Jun 2016

'Nonserious' side effects may lead to antiplatelet discontinuation

Most adverse events that lead patients to discontinue antiplatelet drugs are not rated as serious by clinical trial criteria, shows analysis of the PEGASUS-TIMI 54 trial.

16 Jun 2016

Cerebral vessel disease increases Alzheimer's dementia risk

Cerebral vessel disease may be an under-recognised risk factor for Alzheimer's disease dementia, say researchers.

16 Jun 2016

Potential non-invasive screening biomarker for SSc-PAH

Serum asymmetric dimethylarginine may be an effective non-invasive screening biomarker for systemic sclerosis-related pulmonary arterial hypertension, study findings indicate.

16 Jun 2016

IGF-1 protein may be key to prevent heart disease in older adults

As men and women grow older, their chances for coronary heart disease also increase. Atherosclerosis is a condition in which plaque builds up inside the arteries, which can lead to serious problems, including heart attacks, strokes or even death.

16 Jun 2016

New FcMBL-based pathogen-detecting assay could rapidly detect systemic infections

To date, there are no methods that can quickly and accurately detect pathogens in blood to allow the diagnosis of systemic bloodstream infections that can lead to life-threatening sepsis.

15 Jun 2016

MicroRNA plays role in blocking development of arterial thrombosis

The dangers of arterial thrombosis - the formation of blood clots that can block arteries and cause illness or death - can escalate through a vicious cycle of coagulation and inflammation.

15 Jun 2016

Female migraine patients have increased cardiovascular disease risk

Women who suffer from migraine headaches have a slightly increased risk of developing cardiovascular disease in later life. A team of researchers led by Prof. Tobias Kurth, Head of the Institute of Public Health at Charité - Universitätsmedizin Berlin, has now been able to establish the following: female migraine patients have a higher risk of stroke or heart attacks than women without migraine.

15 Jun 2016

Right ventricular echocardiography predicts targeted therapy outcome in PAH

Echocardiography re-assessment of right ventricular function after targeted therapy is sufficient to predict subsequent prognosis in patients with pulmonary arterial hypertension, say researchers.

15 Jun 2016

Liraglutide cardioprotective in high-risk Type 2 diabetes patients

Findings of the LEADER trial show that liraglutide treatment may confer a reduced risk of cardiovascular events in patients with Type 2 diabetes and a high vascular risk.

15 Jun 2016

Stroke can cause long-term damage to blood-spinal cord barrier, study finds

A team of researchers at the University of South Florida investigating the short and long-term effects of ischemic stroke in a rodent model has found that stroke can cause long-term damage to the blood-spinal cord barrier (BSCB), creating a "toxic environment" in the spinal cord that might leave stroke survivors susceptible to motor dysfunction and disease pathology.

14 Jun 2016

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

A study in the Journal of the American Society of Nephrology suggests a new therapeutic approach to treat the development of chronic kidney disease secondary to chronic heart failure, known as cardiorenal syndrome type 2.

14 Jun 2016