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Drug used to treat TB may also act against various infections, says study

A drug under clinical trials to treat tuberculosis could be the basis for a class of broad-spectrum drugs that act against various bacteria, fungal infections and parasites, yet evade resistance, according to a study by University of Illinois chemists and collaborators.

18 Apr 2014

Research by UCI, Salk Institute points to novel therapies for minimizing stroke-induced brain damage

By discovering a new mechanism that allows blood to enter the brain immediately after a stroke, researchers at UC Irvine and the Salk Institute have opened the door to new therapies that may limit or prevent stroke-induced brain damage.

18 Apr 2014

Engineering cell-based, biological devices may selectively kill cancer cells without disrupting healthy cells

A Northwestern University synthetic biology team has created a new technology for modifying human cells to create programmable therapeutics that could travel the body and selectively target cancer and other sites of disease.

18 Apr 2014

Scientist receives $1.8M defense grant from Kessler Foundation for spinal cord injury research

Kessler Foundation has been named awardee of a three-year grant for $1.8 million from the Department of Defense Spinal Cord Injury Research Program. Gail Forrest, PT, PhD, is principal investigator for the randomized, double-blinded, controlled, multi-site clinical trial, which will test strategies to improve bone and muscle strength after spinal cord injury. Dr. Forrest is assistant director of Human Performance & Engineering Research at Kessler Foundation.

18 Apr 2014

Queen's University professor elected as Fellow of European Academy of Cancer Sciences

Queen's University Belfast's Vice-Chancellor, Professor Patrick Johnston, whose work has transformed cancer care in Northern Ireland, has been elected as a Fellow of the European Academy of Cancer Sciences.

18 Apr 2014

B1/Cdk1 protein which plays key role in cell division also boosts power of mitochondrial activity

An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process.

18 Apr 2014

Hydrogen sulfide regulates bone marrow mesenchymal stem cells, shows study

Stem cells in bone marrow need to produce hydrogen sulfide in order to properly multiply and form bone tissue, according to a new study from the Center for Craniofacial Molecular Biology at the Herman Ostrow School of Dentistry of USC.

18 Apr 2014

Princeton professor receives Agilent Thought Leader Award to research on cellular metabolism activity

Agilent Technologies Inc. today announced that Joshua Rabinowitz, M.D., Ph.D., professor at Princeton University's Department of Chemistry and the Lewis-Sigler Institute for Integrative Genomics, has received an Agilent Thought Leader Award to support his work on quantitative analysis of cellular metabolism.

18 Apr 2014

Agios begins AG-348 Phase 1 study to treat PK deficiency

Agios Pharmaceuticals, Inc., a leader in the fields of cancer metabolism and inborn errors of metabolism (IEM), today announced dose administration of AG-348 in a Phase 1 study in healthy volunteers.

18 Apr 2014

New research may help scientists develop treatments or vaccines for Dengue fever

Two recent papers by a University of Colorado School of Medicine researcher and colleagues may help scientists develop treatments or vaccines for Dengue fever, West Nile virus, Yellow fever, Japanese encephalitis and other disease-causing flaviviruses.

18 Apr 2014

New insight provides potential to improve treatment for sepsis

In a review published in the April issue of Immunity, Kevin J. Tracey, MD, president of The Feinstein Institute for Medical Research, says it's time to take a fresh look at the medical community's approach to treating sepsis, which kills millions worldwide every year, including more than 200,000 Americans.

18 Apr 2014

Research provides fresh insight into structure of sodium channels

Sodium channels are implicated in many serious conditions such as heart disease, epilepsy and pain, making them an important potential target for drug therapies. Unfortunately, there is still much scientists do not know about the molecules.

18 Apr 2014

Special supplement explores the causes of distracted driving among teens

Motor vehicle crashes rank as the leading cause of teen deaths and in 2008, 16% of all distraction-related fatal automobile crashes involved drivers under 20 years of age.

17 Apr 2014

Study provides better understanding of intestinal pathologies associated with inherited, infectious diseases

The "brush border" - a densely packed array of finger-like projections called microvilli - covers the surfaces of the cells that line our intestines.

17 Apr 2014

College of American Pathologists and ASC sign MOU to advance delivery of cytopathology services

The College of American Pathologists and the American Society of Cytopathology announced today the signing of a memorandum of understanding (MOU) to collaborate on initiatives to advance the delivery of cytopathology services and improve patient care.

17 Apr 2014

Research sheds new light on the development of HPV-associated cancer

It's long been known that certain strains of human papillomavirus (HPV) cause cancer. Now, researchers at The Ohio State University have determined a new way that HPV might spark cancer development - by disrupting the human DNA sequence with repeating loops when the virus is inserted into host-cell DNA as it replicates.

17 Apr 2014

Boehringer grants volasertib 'orphan drug designation' for treatment of patients with AML

Boehringer Ingelheim announced today that the US Food and Drug Administration (FDA) and the European Commission have granted volasertib* 'orphan drug designation' for the treatment of patients with acute myeloid leukaemia (AML).

17 Apr 2014

Study shows R9-caPep compound blocks PCNA actions in neuroblastoma cells

Neuroblastoma is one of the deadliest childhood cancers, accounting for 15 percent of pediatric cancer deaths. For patients with high-risk neuroblastomas, the five-year survival rate is 40 to 50 percent even with the most rigorous treatments available today.

17 Apr 2014

Researchers uncover mechanism that may help explain severe forms of schistosomiasis

Researchers at the Sackler School of Graduate Biomedical Sciences at Tufts and Tufts University School of Medicine (TUSM) have uncovered a mechanism that may help explain the severe forms of schistosomiasis, or snail fever, which is caused by schistosome worms and is one of the most prevalent parasitic diseases in the world. The study in mice, published online in The Journal of Immunology, may also offer targets for intervention and amelioration of the disease.

17 Apr 2014

Scientists discover protein structure that helps common fungal pathogen to infect humans

A team that includes scientists from the School of Medicine at The University of Texas Health Science Center at San Antonio, Johns Hopkins University and St. Mary's University reported the structure of a protein that helps a common fungus to infect the body.

17 Apr 2014

Cell News and Research

Drug used to treat TB may also act against various infections, says study

Research by UCI, Salk Institute points to novel therapies for minimizing stroke-induced brain damage

Engineering cell-based, biological devices may selectively kill cancer cells without disrupting healthy cells

Scientist receives $1.8M defense grant from Kessler Foundation for spinal cord injury research

Queen's University professor elected as Fellow of European Academy of Cancer Sciences

B1/Cdk1 protein which plays key role in cell division also boosts power of mitochondrial activity

Hydrogen sulfide regulates bone marrow mesenchymal stem cells, shows study

Princeton professor receives Agilent Thought Leader Award to research on cellular metabolism activity

Agios begins AG-348 Phase 1 study to treat PK deficiency

New research may help scientists develop treatments or vaccines for Dengue fever

New insight provides potential to improve treatment for sepsis

Research provides fresh insight into structure of sodium channels

Special supplement explores the causes of distracted driving among teens

Study provides better understanding of intestinal pathologies associated with inherited, infectious diseases

College of American Pathologists and ASC sign MOU to advance delivery of cytopathology services

Research sheds new light on the development of HPV-associated cancer

Boehringer grants volasertib 'orphan drug designation' for treatment of patients with AML

Study shows R9-caPep compound blocks PCNA actions in neuroblastoma cells

Researchers uncover mechanism that may help explain severe forms of schistosomiasis

Scientists discover protein structure that helps common fungal pathogen to infect humans

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