Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Surgeon performs first-ever retrograde gene therapy on human heart

Ernie Lively moved to a scenic home in the mountains of Wasatch County to escape the hectic pace of Hollywood when he retired. But retirement didn't provide Lively with the active lifestyle he craved because of simple reality: His heart was failing.

28 Nov 2013

Study highlights unique barriers for African Americans with hypertension

For African-Americans who have hypertension, controlling their high blood pressure is critical to avoid serious complications. However, a history of racial discrimination and/or mistrust in their physicians often causes them to skip taking their necessary medication, finds a new study in the American Journal of Public Health.

27 Nov 2013

Edison initiates coverage of biotechnology company focused on adult stem therapies

Edison Investment Research, a leading international investment research firm, announces the initiation of coverage of Mesoblast (MSB: ASX), an Australian-headquartered biotechnology company focused on adult stem therapies.

27 Nov 2013

AATS, cardiovascular professional societies release overview of transcatheter therapies for mitral regurgitation

AATS and three cardiovascular professional societies today released an overview of transcatheter therapies for mitral regurgitation.

26 Nov 2013

CHMP adopts positive opinion for ABRAXANE with gemcitabine for treatment of metastatic pancreas

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation, today announced that the European Medicines Agency's: Committee for Medicinal Products for Human Use has adopted a positive opinion for ABRAXANE (paclitaxel formulated as albumin bound nanoparticles, or nab-paclitaxel) in combination with gemcitabine for first-line treatment of adult patients with metastatic adenocarcinoma of the pancreas.

25 Nov 2013

Sorin Group receives CE Mark approval for Solo Smart stentless aortic valve

Sorin Group, a global medical company and a leader in the treatment of cardiovascular diseases, announced today that it has received CE Mark approval for the Solo Smart stentless aortic valve.

23 Nov 2013

NEXAVAR tablets receive FDA approval for treatment of patients with thyroid cancer

Bayer HealthCare and Onyx Pharmaceuticals, Inc., an Amgen subsidiary, today announced that the U.S. Food and Drug Administration has approved a supplemental New Drug Application for the oral multi-kinase inhibitor NEXAVAR (sorafenib) tablets for the treatment of patients with locally recurrent or metastatic, progressive, differentiated thyroid carcinoma refractory to radioactive iodine treatment.

23 Nov 2013

New technique can diagnose cancer with high degree of accuracy, say researchers

A team of researchers from UCLA and Harvard University have demonstrated a technique that, by measuring the physical properties of individual cells in body fluids, can diagnose cancer with a high degree of accuracy.

21 Nov 2013

Type 2 diabetes cytokine elevation places teeth at risk

Scientists have detected significant differences in the cytokine and chemokine make up of gingival crevicular fluid taken from chronic periodontitis patients with uncontrolled Type 2 diabetes and those without.

21 Nov 2013

Study: Patients staying on medications does not lower hospital readmission rates

A targeted effort to help high-risk heart failure patients stay on their medications did improve adherence to drug regimens, but had surprisingly little effect lowering hospital readmission rates, according to a study at Duke Medicine.

21 Nov 2013

Top-performing hospitals have fewer readmissions from all diagnoses and time periods after discharge

Checking back into the hospital within 30 days of discharge is not only bad news for patients, but also for hospitals, which now face financial penalties for high readmissions. The key to reducing readmissions may be focusing on the whole patient, rather than the specific conditions that caused their hospitalizations, according to a new study by Yale School of Medicine researchers.

21 Nov 2013

Smokers who quit faster may be able to lower risk of cardiovascular disease-related deaths

Cigarette smokers who are over 65 years of age may be able to lower their risk of cardiovascular disease-related deaths to the level of never-smokers when they quit faster than previously reported, according to research presented at the American Heart Association's Scientific Sessions 2013.

21 Nov 2013

UK's first gene therapy trial for patients with chronic heart failure begins at GJNH

The UK’s first gene therapy trial for advanced heart failure, CUPID 2, has officially begun at the Golden Jubilee National Hospital; with the first candidate recently being administered with a dose of the MYDICAR treatment.

21 Nov 2013

Study identifies possible link between orthostatic hypotension and atrial fibrillation

Results of a Johns Hopkins-led study have identified a possible link between a history of sudden drops in blood pressure and the most common form of irregular heartbeat.

21 Nov 2013

BioCardia reports positive results for Transendocardial Autologous Cells in Ischemic Heart Failure Trial

BioCardia, Inc., a leader in cardiovascular regenerative medicine, today announced positive 12-month results for the randomized Transendocardial Autologous Cells (MSC or BMC) in Ischemic Heart Failure Trial (TAC-HFT).

20 Nov 2013

Study shows cognitively impaired older adults released from hospital less likely to be rehospitalized

Cognitively impaired older adults released from the hospital are less likely to be rehospitalized within 30 days if they go to a nursing home than if they return to their own home or the home of a family member, according to an Indiana University and Regenstrief Institute study.

20 Nov 2013

Research provides first rigorous comparison of 2 surgical approaches for severe heart valve disease

New research presented today at the 2013 Scientific Sessions of the American Heart Association by researchers at the Perelman School of Medicine at the University of Pennsylvaniafound no difference in outcomes at one-year between two recommended surgical options for treating ischemic mitral regurgitation (IMR) - repair of the leaky valve or its replacement with an artificial valve.

20 Nov 2013

Patients at highest risk for suffering full-blown ischemic attack less likely to receive optimal care

Among thousands of hospital patients treated for a "mini stroke," those who were at highest risk for suffering a full-blown ischemic attack were less likely to received optimal care, according to a study led by researchers at Duke Medicine.

20 Nov 2013

Researchers report long-term benefits of gene therapy in advanced heart failure patients

Researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai reported the long-term benefits of a single dose of their gene therapy AAV1/SERCA2a in advanced heart failure patients on Nov. 19 at the American Heart Association Scientific Sessions 2013.

20 Nov 2013

Heart failure patients receiving LVAD may benefit from injection of powerful cells directly into heart

A multicenter team of researchers within the NIH-funded Cardiothoracic Surgical Trials Network, led by Icahn School of Medicine at Mount Sinai, have found end-stage heart failure patients who receive a surgically implanted left ventricular assist device heart pump may also benefit from a single dose of millions of powerful cells injected directly into their heart during surgery.

19 Nov 2013

Heart Failure News and Research

Further Reading

Surgeon performs first-ever retrograde gene therapy on human heart

Study highlights unique barriers for African Americans with hypertension

Edison initiates coverage of biotechnology company focused on adult stem therapies

AATS, cardiovascular professional societies release overview of transcatheter therapies for mitral regurgitation

CHMP adopts positive opinion for ABRAXANE with gemcitabine for treatment of metastatic pancreas

Sorin Group receives CE Mark approval for Solo Smart stentless aortic valve

NEXAVAR tablets receive FDA approval for treatment of patients with thyroid cancer

New technique can diagnose cancer with high degree of accuracy, say researchers

Type 2 diabetes cytokine elevation places teeth at risk

Study: Patients staying on medications does not lower hospital readmission rates

Top-performing hospitals have fewer readmissions from all diagnoses and time periods after discharge

Smokers who quit faster may be able to lower risk of cardiovascular disease-related deaths

UK's first gene therapy trial for patients with chronic heart failure begins at GJNH

Study identifies possible link between orthostatic hypotension and atrial fibrillation

BioCardia reports positive results for Transendocardial Autologous Cells in Ischemic Heart Failure Trial

Study shows cognitively impaired older adults released from hospital less likely to be rehospitalized

Research provides first rigorous comparison of 2 surgical approaches for severe heart valve disease

Patients at highest risk for suffering full-blown ischemic attack less likely to receive optimal care

Researchers report long-term benefits of gene therapy in advanced heart failure patients

Heart failure patients receiving LVAD may benefit from injection of powerful cells directly into heart

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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