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TSRI scientists receive $2.3M to study viruses that cause tropical diseases

The outbreak of dengue fever that infected some 20 people in Florida's Martin County late last year unnerved many who feared the tropical disease had once again established a foothold in Florida. The last outbreaks occurred in 2009 and 2010 in Key West—before that, the disease hadn't struck Florida in more than 70 years.

28 Mar 2014

Researchers find new drug target for mitochondrial dysfunction

Mitochondria, long known as "cellular power plants" for their generation of the key energy source adenosine triphosphate (ATP), are essential for proper cellular functions. Mitochondrial defects are often observed in a variety of diseases, including cancer, Alzheimer's disease, and Parkinson's disease, and are the hallmarks of a number of genetic mitochondrial disorders whose manifestations range from muscle weakness to organ failure. Despite a fairly strong understanding of the pathology of such genetic mitochondrial disorders, efforts to treat them have been largely ineffective.

28 Mar 2014

$Patrys reports final results from PAT-SM6 Phase I/IIa study in patients with refractory or relapsed MM$

Patrys reports final results from PAT-SM6 Phase I/IIa study in patients with refractory or relapsed MM

Patrys Limited, a clinical stage biotechnology company, is pleased to announce the final results from its Phase I/IIa, open-label study in patients with refractory or relapsed multiple myeloma (MM).

28 Mar 2014

Research findings help explain rare genetic disorder that causes immunodeficiency syndrome

IRCM researchers led by Javier M. Di Noia, PhD, uncovered a new function of AID, a crucial enzyme for the immune response. The discovery, recently published by the scientific journal Proceedings of the National Academy of Sciences, helps explain a rare genetic disorder that causes an immunodeficiency syndrome.

28 Mar 2014

BioTek to highlight latest microplate instrumentation technologies at Analytica 2014

BioTek Instruments, Inc., will highlight their latest microplate instrumentation technologies, designed to automate and improve lab efficiency, at Hall A3, Stand #310 during Analytica 2014, the 24th International Trade Fair for Laboratory Technology, Analysis and Biotechnology. The exhibition will be held April 1-4 at the Munich Trade Fair Centre / ICM in Munich, Germany.

28 Mar 2014

Cells measure surface area using cdr2p protein

One of the scientists who revealed how plants "do maths" can now reveal how cells take measurements of size. Size is important to cells as it determines when they divide.

28 Mar 2014

IRB researchers identify dual role of p38 protein in colon cancer

A team headed by Angel R. Nebreda at the Institute for Research in Biomedicine identifies a dual role of the p38 protein in colon cancer. The study demonstrates that, on the one hand, p38 is important for the optimal maintenance of the epithelial barrier that protects the intestine against toxic agents, thus contributing to decreased tumour development.

28 Mar 2014

Scientists move a step closer to preserving fertility in young boys with cancer

Scientists have moved a step closer to being able to preserve fertility in young boys who undergo chemotherapy and radiation treatments for cancer. The new research, published in Fertility and Sterility, the journal of the American Society for Reproductive Medicine, addresses the safety of an option scientists are developing for boys who aren't sexually mature and cannot bank sperm.

28 Mar 2014

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Novartis today announced that The New England Journal of Medicine (NEJM) published clinical trial results showing the investigational compound LDK378 (ceritinib) achieved an overall response rate (ORR, including complete response [CR] and partial response [PR]) of 58% and a median progression-free survival (PFS) of seven months in adults with advanced anaplastic lymphoma kinase positive (ALK+) non-small cell lung cancer (NSCLC) who received 400 mg or higher of LDK378 per day.

28 Mar 2014

Discovery could lead to new medications for cancer, say Rice University scientists

A new understanding of proteins at the nexus of a cell's decision to survive or die has implications for researchers who study cancer and age-related diseases, according to biophysicists at the Rice University-based Center for Theoretical Biological Physics.

28 Mar 2014

Scientists identify two markers that predict patient's resistance to radiation therapy for cancer

An international team of researchers, led by Beaumont Health System's Jan Akervall, M.D., Ph.D., looked at biomarkers to determine the effectiveness of radiation treatments for patients with squamous cell cancer of the head and neck.

28 Mar 2014

Tgen professor to receive 2014 Hope Funds Award for developing numerous cancer treatments

Dr. Daniel D. Von Hoff, who has been instrumental in developing numerous new cancer treatments, is among this year's recipients of the Award of Excellence from the Hope Funds for Cancer Research.

28 Mar 2014

Researchers provide new clues for adult vertebrate tissue regeneration

The reason why some animals can regenerate tissues after severe organ loss or amputation while others, such as humans, cannot renew some structures has always intrigued scientists. In a study now published in PLOS ONE, a research group from Instituto Gulbenkian de Ci-ncia (IGC, Portugal) led by Joaqu-n Rodr-guez Le-n provided new clues to solve this central question by investigating regeneration in an adult vertebrate model: the zebrafish.

27 Mar 2014

Tumor suppressor gene linked to stem cell function

Just as archeologists try to decipher ancient tablets to discern their meaning, UT Southwestern Medical Center cancer biologists are working to decode the purpose of an ancient gene considered one of the most important in cancer research.

27 Mar 2014

Schizophrenia Research: Cognition, an online open access journal from Elsevier

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the launch of Schizophrenia Research: Cognition, a new open access journal dedicated to publishing original research, concise research reports, brief reports, letters to the editor, and review papers addressing the role of cognitive functioning in schizophrenia.

27 Mar 2014

Cytrx releases statement in response to two recent lawsuits

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, today issued the following statement in response to two recent lawsuits filed in the name of CytRx shareholders:

27 Mar 2014

Study to understand how protein motor works for development of targeted cancer therapies

Researchers at Warwick Medical School have shown for the first time how a protein motor, Kif15, uses acrobatic flexibility to navigate within the mitotic spindle. Understanding how it works could prove vital for the development of targeted cancer therapies.

27 Mar 2014

Treatment option for women with squamous cell carcinoma of the vulva

A team of researchers from Women & Infants Hospital of Rhode Island commanded a national stage to present the results of a study evaluating the use of sentinel lymph node dissection in women with vulvar malignancies, and then follow the patients for complications and recurrence.

27 Mar 2014

Johns Hopkins researchers use 3-D MRI scans to accurately measure tumor viability and death

In a series of studies involving 140 American men and women with liver tumors, researchers at Johns Hopkins have used specialized 3-D MRI scans to precisely measure living and dying tumor tissue to quickly show whether highly toxic chemotherapy - delivered directly through a tumor's blood supply - is working.

27 Mar 2014

Orthofix net sales reduce 10% to $106.1M in fourth quarter 2013

Orthofix International N.V., today reported results for the fourth quarter and full year ended Dec. 31, 2013. For full-year 2013, net sales were $400.5 million, decreasing 11 percent on a reported basis and constant currency basis from $447.6 million in the prior year.

27 Mar 2014

Cell News and Research

TSRI scientists receive $2.3M to study viruses that cause tropical diseases

Researchers find new drug target for mitochondrial dysfunction

Patrys reports final results from PAT-SM6 Phase I/IIa study in patients with refractory or relapsed MM

Research findings help explain rare genetic disorder that causes immunodeficiency syndrome

BioTek to highlight latest microplate instrumentation technologies at Analytica 2014

Cells measure surface area using cdr2p protein

IRB researchers identify dual role of p38 protein in colon cancer

Scientists move a step closer to preserving fertility in young boys with cancer

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Discovery could lead to new medications for cancer, say Rice University scientists

Scientists identify two markers that predict patient's resistance to radiation therapy for cancer

Tgen professor to receive 2014 Hope Funds Award for developing numerous cancer treatments

Researchers provide new clues for adult vertebrate tissue regeneration

Tumor suppressor gene linked to stem cell function

Schizophrenia Research: Cognition, an online open access journal from Elsevier

Cytrx releases statement in response to two recent lawsuits

Study to understand how protein motor works for development of targeted cancer therapies

Treatment option for women with squamous cell carcinoma of the vulva

Johns Hopkins researchers use 3-D MRI scans to accurately measure tumor viability and death

Orthofix net sales reduce 10% to $106.1M in fourth quarter 2013

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