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Women are most likely to experience serious pain following knee replacement than men

Middle-aged women with rheumatoid arthritis or arthritis resulting from an injury are among the patients most likely to experience serious pain following a knee replacement, researchers from Hospital for Special Surgery (HSS) in New York have found.

12 Mar 2014

MIT biologists discover how cancer cells make their escape

About 90 percent of cancer deaths are caused by tumors that have spread from their original locations. This process, known as metastasis, requires cancer cells to break loose from their neighbors and from the supportive scaffold that gives tissues their structure.

11 Mar 2014

Research could lead to 'smart bandages' to help heal wounds

Researchers at the University of California, Berkeley, found that an electrical current can be used to orchestrate the flow of a group of cells, an achievement that could establish the basis for more controlled forms of tissue engineering and for potential applications such as "smart bandages" that use electrical stimulation to help heal wounds.

11 Mar 2014

Researchers suggest potential treatment target for HCMV infection

Discovering where a common virus hides in the body has been a long-term quest for scientists. Up to 80 percent of adults harbor the human cytomegalovirus (HCMV), which can cause severe illness and death in people with weakened immune systems.

11 Mar 2014

Damage to brain cells plays role in development of epilepsy after traumatic brain injury

Traumatic brain injury is a risk factor for epilepsy, though the relationship is not understood. A new study in mice, published in Cerebral Cortex, identifies increased levels of a specific neurotransmitter as a contributing factor connecting traumatic brain injury (TBI) to post-traumatic epilepsy. The findings suggest that damage to brain cells called interneurons disrupts neurotransmitter levels and plays a role in the development of epilepsy after a traumatic brain injury.

11 Mar 2014

Monash University research offers new hope to people with heart attacks

Melbourne scientists are a step closer to creating a new drug to stop a heart attack in its tracks and reduce the damage caused, without any side effects.

11 Mar 2014

Rexahn reports initial results from Supinoxin Phase I trial in patients with solid cancer tumors

Rexahn Pharmaceuticals, Inc., a clinical stage biopharmaceutical company announced today initial data for the Phase I dose-escalation clinical trial of SupinoxinTM (RX-5902) initiated in August 2013. This trial was designed to study safety and efficacy in patients with solid cancer tumors.

11 Mar 2014

Synta Pharmaceuticals' Hsp90 inhibitor ganetespib selected for study in I-SPY 2 TRIAL

Synta Pharmaceuticals Corp. and QuantumLeap Healthcare Collaborative today announced that Synta's lead drug candidate, the Hsp90 inhibitor ganetespib, has been selected for study in the I-SPY 2 TRIAL (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2).

11 Mar 2014

Clinipace Worldwide closes merger with Choice Pharma

Clinipace Worldwide, a global digital contract research organization (dCRO), announced today the closing of its merger with Choice Pharma, a Pan-Asian contract research organization. Bringing these organizations together strengthens Clinipace Worldwide's operational and therapeutic expertise in Asia, a region in high demand by Clinipace's clients.

11 Mar 2014

NeuroDerm enrolls patients in second ND0612 Phase II clinical trial for treatment of Parkinson's disease

NeuroDerm, Ltd. announced today that enrollment of patients is ongoing in its second Phase II clinical trial of ND0612, a novel drug formulation for the treatment of Parkinson's disease. ND0612 is a proprietary levodopa/carbidopa liquid formulation under development for continuous subcutaneous administration through a patch pump. It is designed to provide steady levodopa blood levels for the treatment of Parkinson's disease.

11 Mar 2014

Exosome Diagnostics closes Series B financing round with the raising of $27 million

Exosome Diagnostics today announced the initial close of its Series B financing round with the raising of $27 million. Proceeds will be used to advance development of the Company's proprietary platform technology and commercial programs for non-invasive, fluid-based molecular diagnostics in oncology, neurodegenerative diseases and other clinical areas.

11 Mar 2014

Bayer and Onyx announce Phase 3 trial evaluating use of NEXAVAR for patients with HCC after local ablation

Bayer HealthCare Pharmaceuticals Inc. and Onyx Pharmaceuticals, Inc., an Amgen subsidiary (Nasdaq: AMGN), today announced that a Phase 3 trial evaluating the investigational use of NEXAVAR® (sorafenib) tablets as an adjuvant treatment for patients with hepatocellular carcinoma (HCC), or liver cancer, who had no detectable disease after surgical resection or local ablation, did not meet its primary endpoint of improving recurrence-free survival.

11 Mar 2014

UTSA College of Sciences faculty members honored at 2014 Annual Meeting of AAAS

UTSA College of Sciences faculty members Andrew Tsin, Garry Cole and Donald Kurtz were honored recently at the 2014 Annual Meeting of the American Association for the Advancement of Science (AAAS) in Chicago.

11 Mar 2014

Researchers investigate stickiness of leukaemia cells and its link to drug resistance

Researchers in Manchester have investigated the stickiness of leukaemia cells, and whether this is linked to drug resistance.

11 Mar 2014

Aged mice lacking antioxidant protein Nrf2 show poor stem cell regeneration

Good news for lifelong exercisers: Along with its salutary effects on the heart, weight, and other facets of health, physical activity also helps to regenerate muscle mass, which tends to diminish as people age.

11 Mar 2014

Thirteen graduate students to receive 2014 Harold M. Weintraub Graduate Student Award

Thirteen graduate students from institutes throughout North America have been chosen to receive the 2014 Harold M. Weintraub Graduate Student Award sponsored by the Basic Sciences Division of Fred Hutchinson Cancer Research Center.

11 Mar 2014

Controlled TB vaccine trial designed to study prevention of Mtb infection by vaccination

Aeras today announced the initiation of the first randomized, controlled tuberculosis (TB) vaccine trial designed to study prevention of Mycobacterium tuberculosis (Mtb) infection by vaccination.

11 Mar 2014

Novel treatment strategy during transplantation surgery could spare patients from rejection

Organ-transplant recipients often reject donated organs, but a new, two-pronged strategy developed by UC San Francisco researchers to specifically weaken immune responses that target transplanted tissue has shown promise in controlled experiments on mice.

11 Mar 2014

Promethera Biosciences, EMD Millipore partner to develop ready-to-use microfluidic perfusion liver assay

Promethera Biosciences, a company that develops innovative therapies for the treatment of liver diseases, today announces a collaboration with EMD Millipore to develop an improved ready-to-use microfluidic perfusion liver assay. This new product is designed to perform more robust studies in pre-clinical toxicity and drug metabolism.

11 Mar 2014

Researchers identify microbe that 'eats' electricity

There have been plenty of fad diets that captured the public's imagination over the years, but Harvard scientists have identified what may be the strangest of them all - sunlight and electricity.

11 Mar 2014

Cell News and Research

Women are most likely to experience serious pain following knee replacement than men

MIT biologists discover how cancer cells make their escape

Research could lead to 'smart bandages' to help heal wounds

Researchers suggest potential treatment target for HCMV infection

Damage to brain cells plays role in development of epilepsy after traumatic brain injury

Monash University research offers new hope to people with heart attacks

Rexahn reports initial results from Supinoxin Phase I trial in patients with solid cancer tumors

Synta Pharmaceuticals' Hsp90 inhibitor ganetespib selected for study in I-SPY 2 TRIAL

Clinipace Worldwide closes merger with Choice Pharma

NeuroDerm enrolls patients in second ND0612 Phase II clinical trial for treatment of Parkinson's disease

Exosome Diagnostics closes Series B financing round with the raising of $27 million

Bayer and Onyx announce Phase 3 trial evaluating use of NEXAVAR for patients with HCC after local ablation

UTSA College of Sciences faculty members honored at 2014 Annual Meeting of AAAS

Researchers investigate stickiness of leukaemia cells and its link to drug resistance

Aged mice lacking antioxidant protein Nrf2 show poor stem cell regeneration

Thirteen graduate students to receive 2014 Harold M. Weintraub Graduate Student Award

Controlled TB vaccine trial designed to study prevention of Mtb infection by vaccination

Novel treatment strategy during transplantation surgery could spare patients from rejection

Promethera Biosciences, EMD Millipore partner to develop ready-to-use microfluidic perfusion liver assay

Researchers identify microbe that 'eats' electricity

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