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Low-dose oral interferon may reduce risk of HCV relapse in patients with mild liver fibrosis

Chronic hepatitis C virus (HCV) infection can lead to serious diseases such as cirrhosis and cancer of the liver, so viral clearance and prevention of relapse are important treatment goals.

6 Mar 2014

Study to understand role of bacterium in heart valve disease

A disease-causing bacterium found in the mouth needs manganese, a trace mineral, in order to cause a serious heart infection, according to a preclinical study led by researchers at Virginia Commonwealth University Philips Institute for Oral Health Research in the School of Dentistry.

6 Mar 2014

Specific protein has vital role in controlling symptoms of allergic asthma, say researchers

An enzyme that helps maintain immune system function by "throwing away" a specific protein has a vital role in controlling symptoms of allergic asthma, new research in mice suggests.

6 Mar 2014

Scientists discover fundamental aggravating factor in autoimmune diseases

Scientists in Freiburg may have discovered a fundamental aggravating factor in autoimmune diseases. If B-lymphocytes lack the protein PTP1B, the cells will become hyperactive for stimulatory signals and can thus promote an autoimmune attack.

6 Mar 2014

Expression of MYC gene important for neurogenesis in the spinal cord

Research from Karolinska Institutet in Sweden suggests that the expression of the so called MYC gene is important and necessary for neurogenesis in the spinal cord. The findings are being published in the journal EMBO Reports.

6 Mar 2014

Verastem presents preliminary data from VS-6063 Phase 1 trial in Japanese patients with solid tumors

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, today presented preliminary data from an ongoing First-in-Asia Phase 1 trial of VS-6063 in Japanese patients with advanced solid tumors, including one patient with mesothelioma. The Phase 1 study assessed the safety and pharmacokinetics of single agent VS-6063.

5 Mar 2014

Treating cystic fibrosis: an interview with Simon Bedson, Senior Vice President and International General Manager at Vertex

Cystic fibrosis is a rare, life-shortening genetic disease for which there is no cure. It affects more than 75,000 people worldwide. In CF, thick, sticky mucus blocks the passages in many organs, leading to a variety of symptoms. In particular, mucus builds up and clogs airways in the lungs making it easier for bacteria to grow.

5 Mar 2014

Agenus reports net loss attributable to common stockholders of $5.8 million for Q4 2013

Agenus Inc., a biopharmaceutical company developing a portfolio of immuno-oncology candidates, including checkpoint modulators (CPMs), heat shock protein vaccines and adjuvants, today announced its financial results and business highlights for the fourth quarter and year ended December 31, 2013.

5 Mar 2014

Kamada initiates Phase 2/3 clinical trial of Glassia to treat pediatric patients with T1D

Kamada Ltd. (NASDAQ:KMDA) (TASE:KMDA), a plasma-derived protein therapeutics company focused on orphan indications, announces the initiation of a Phase 2/3 clinical trial of Glassia®, the Company's proprietary human Alpha-1 Antitrypsin (AAT), to treat newly diagnosed pediatric patients with type 1 diabetes (T1D).

5 Mar 2014

Metabolon agrees to provide biochemical profiling services to Human Longevity

Metabolon, Inc., the world's leading commercial-stage metabolomics company, announces the signing of an agreement with newly-launched Human Longevity Inc., whereby Metabolon will provide biochemical profiling services to assist HLI in its mission to tackle diseases of aging by building the world's largest and most complete human genotype, microbiome and phenotype database.

5 Mar 2014

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that could bring new diagnostic and treatment methods.

5 Mar 2014

New study shows male hormones play important role; may enhance IVF therapy in women

Several fertility clinics across the country are beginning to administer testosterone, either through a patch or a gel on the skin, to increase the number of eggs produced by certain women undergoing in vitro fertilization (IVF).

5 Mar 2014

Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

For the first time, scientists have demonstrated the effectiveness of a small-molecule drug in protecting nonhuman primates from the lethal Marburg virus. Their work, published online in the journal Nature, is the result of a continuing collaboration between Army scientists and industry partners that also shows promise for treating a broad range of other viral diseases.

5 Mar 2014

New PhoneSoap Charger is most effective way to kill bacteria growing on cell phones

Cell phones have become our constant companions, and as a result, they are exposed to many bacteria and viruses. When we open a door, shake hands, use an ATM or dozens of other daily tasks, our hands come in contact with germs, and numerous studies have shown that a significant number of bacteria, such as the flu virus, staph, strep, E. coli, and salmonella, are transferred from our hands to our cell phones every time we pick them up.

5 Mar 2014

Plymouth University enters partnership with Brain Tumour Research

Patients, carers, scientists, clinicians and charities from across the UK are heading to Westminster today for the launch of a ground-breaking new collaborative partnership between the charity Brain Tumour Research and Plymouth University Peninsula Schools of Medicine and Dentistry. The announcement will open a new chapter in long-term sustainable and continuous research into the biggest cancer killer of children and adults under 40.

5 Mar 2014

Researchers develop adjuvant which enhances effect of virus transduction

Lentiviruses, which belong to the family of retroviruses, are used as vectors to exchange genetic material in cells and can be used to replace a defective gene as defined by gene therapy.

5 Mar 2014

Set of genes appear to predict which tumors can evade detection by immune system

Johns Hopkins researchers say they have identified a set of genes that appear to predict which tumors can evade detection by the body's immune system, a step that may enable them to eventually target only the patients most likely to respond best to a new class of treatment.

5 Mar 2014

Cell-cycle arrest biomarkers validated for acute kidney injury

Saeed A. Jortani, Ph.D., associate clinical professor in the University of Louisville's Department of Pathology and Laboratory Medicine, headed up one of three labs in the United States involved in determining two new markers for acute kidney injury (AKI). The research group's paper, "Validation of Cell-Cycle Arrest Biomarkers for Acute Kidney Injury Using Clinical Adjudication," was posted online Feb. 25 by the American Journal of Respiratory and Critical Care Medicine.

5 Mar 2014

Low-amplitude electric fields help hard-to-heal chronic wounds

Naturally occurring electricity in our cells is key to how our bodies function, and that includes the healing of wounds.

5 Mar 2014

Berkeley Lab scientists explore bacteria-resistant materials as a line of defense against Staph infection

The bacterium Staphylococcus aureus (S. aureus) is a common source of infections that occur after surgeries involving prosthetic joints and artificial heart valves. The grape-shaped microorganism adheres to medical equipment, and if it gets inside the body, it can cause a serious and even life-threatening illness called a Staph infection. The recent discovery of drug-resistant strains of S. aureus makes matters even worse.

5 Mar 2014

Cell News and Research

Low-dose oral interferon may reduce risk of HCV relapse in patients with mild liver fibrosis

Study to understand role of bacterium in heart valve disease

Specific protein has vital role in controlling symptoms of allergic asthma, say researchers

Scientists discover fundamental aggravating factor in autoimmune diseases

Expression of MYC gene important for neurogenesis in the spinal cord

Verastem presents preliminary data from VS-6063 Phase 1 trial in Japanese patients with solid tumors

Treating cystic fibrosis: an interview with Simon Bedson, Senior Vice President and International General Manager at Vertex

Agenus reports net loss attributable to common stockholders of $5.8 million for Q4 2013

Kamada initiates Phase 2/3 clinical trial of Glassia to treat pediatric patients with T1D

Metabolon agrees to provide biochemical profiling services to Human Longevity

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

New study shows male hormones play important role; may enhance IVF therapy in women

Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

New PhoneSoap Charger is most effective way to kill bacteria growing on cell phones

Plymouth University enters partnership with Brain Tumour Research

Researchers develop adjuvant which enhances effect of virus transduction

Set of genes appear to predict which tumors can evade detection by immune system

Cell-cycle arrest biomarkers validated for acute kidney injury

Low-amplitude electric fields help hard-to-heal chronic wounds

Berkeley Lab scientists explore bacteria-resistant materials as a line of defense against Staph infection

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