pH News and Research

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pH comes from the term “power of Hydrogen”, or the hydrogen ion concentration present in a given solution. It helps to measure the acidity or alkalinity of a substance.

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Scientists from St. Jude Children's Research Hospital have shown that the innate immune sensor, ZBP1, and its associated inflammatory cell death pathway, PANoptosis, are major contributors to the negative effects of interferon treatment and high interferon levels in some COVID-19 patients.

20 May 2022

Montefiore Einstein Cancer Center partners with the Price Family Foundation to advance cancer equity

The National Cancer Institute-designated Montefiore Einstein Cancer Center (MECC) has partnered with the Price Family Foundation to fund eight research teams developing novel cancer therapies and improving cancer outcomes for historically marginalized communities in the Bronx.

20 May 2022

Research provides new insight into how Crimean-Congo hemorrhagic fever virus causes disease

Army scientists determined that the body's own natural immune response contributes to disease severity in mice infected with Crimean-Congo hemorrhagic fever virus (CCHFV), which causes a widespread tick-borne viral infection in humans.

20 May 2022

New training scheme for convolutional neural networks automates cell segmentation and counting

The use of machine learning to perform blood cell counts for diagnosis of disease instead of expensive and often less accurate cell analyzer machines has nevertheless been very labor-intensive as it takes an enormous amount of manual annotation work by humans in the training of the machine learning model.

20 May 2022

Researchers discover how one type of T cell creates functionally distinct, but genetically identical daughter cells

Scientists at St. Jude Children's Research Hospital have solved an immunology puzzle. A CD8+ T cell can have two functionally distinct daughter cells after it divides, despite the cells being genetically identical.

20 May 2022

UNC-Chapel Hill secures $65 million NIH grant for establishing Antiviral Drug Discovery Center

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health awarded the UNC Gillings School of Global Public Health a $65 million grant establishing an Antiviral Drug Discovery Center to develop oral antivirals that can combat pandemic-level viruses like COVID-19.

20 May 2022

Novel brain-permeable Cdk5 inhibitor alters neurobehavior in mice

James Bibb, Ph.D., and colleagues have described a novel preclinical drug that could have the potential to combat depression, brain injury and diseases that impair cognition. The drug, which notably is brain-permeable, acts to inhibit the kinase enzyme Cdk5.

20 May 2022

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

In studies with mouse and human tissue, as well as live mice, Johns Hopkins Medicine researchers report that a snag in the normal process of cleaning up broken DNA in brain cells may hasten the progression of Parkinson's disease.

19 May 2022

Preclinical study may pave the way toward prevention and recovery of neonatal brain injuries

The findings of a new pre-clinical study published in The Journal of Neuroscience are helping pave the way toward better understanding, prevention and recovery of neonatal brain injuries.

19 May 2022

New study helps to better understand re-infection rates and correlates of protection for SARS-CoV-2

By uniting research from 8 cohorts across the U.S., a group of researchers has accelerated collection of data integral in answering questions about immune responses needed for long lasting protection from SARS-CoV-2.

19 May 2022

Black people continue to bear a higher cancer burden even after steady decline in mortality rates

From 1999 to 2019, rates of cancer deaths declined steadily among Black people in the United States. Nevertheless, in 2019, Black people still had considerably higher rates of cancer death than people in other racial and ethnic groups, a large epidemiologic study has found.

19 May 2022

Psychological risk factors may increase chances of hospitalization after COVID-19 diagnosis

People who reported in a survey that they felt worried, depressed or lonely had a greater chance of being hospitalized after a COVID-19 diagnosis, suggests a study funded by the National Institutes of Health.

19 May 2022

Prenatal choline supplementation makes essential nutrient available for fetal development

The nutrient choline – shown to have long-term benefits for children whose mothers consume it during pregnancy – also helps the body more efficiently use an omega 3 fatty acid that is essential for fetal brain, cognition and vision development, a new study finds.

18 May 2022

Molecular pathway allows cells to sense when their lipid supplies become depleted

UT Southwestern researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation.

18 May 2022

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded approximately $577 million to establish nine Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern.

18 May 2022

Study identifies cancer biomarkers based on a type of genetic modification

Biomarkers are often used during the management of cancer to guide treatment decisions and predict patient outcomes. However, it is often difficult to identify appropriate biomarkers that can be consistently reproduced and are easily analyzed with limited patient specimens.

18 May 2022

Health screening and genetic tests may help detect people who carry a gene for familial hypercholesterolemia

Health screening and genetic tests might identify more than 1 million U.S. adults who carry a gene for familial hypercholesterolemia, a common genetic disorder that causes elevated low-density lipoprotein (LDL) cholesterol, known as "bad cholesterol," which may lead to premature heart attack or death, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

18 May 2022

pH News and Research

Further Reading

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Montefiore Einstein Cancer Center partners with the Price Family Foundation to advance cancer equity

Research provides new insight into how Crimean-Congo hemorrhagic fever virus causes disease

New training scheme for convolutional neural networks automates cell segmentation and counting

Researchers discover how one type of T cell creates functionally distinct, but genetically identical daughter cells

UNC-Chapel Hill secures $65 million NIH grant for establishing Antiviral Drug Discovery Center

Novel brain-permeable Cdk5 inhibitor alters neurobehavior in mice

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

Preclinical study may pave the way toward prevention and recovery of neonatal brain injuries

New study helps to better understand re-infection rates and correlates of protection for SARS-CoV-2

Black people continue to bear a higher cancer burden even after steady decline in mortality rates

Psychological risk factors may increase chances of hospitalization after COVID-19 diagnosis

Prenatal choline supplementation makes essential nutrient available for fetal development

Molecular pathway allows cells to sense when their lipid supplies become depleted

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

Study identifies cancer biomarkers based on a type of genetic modification

Health screening and genetic tests may help detect people who carry a gene for familial hypercholesterolemia

Insight into sustained-release drug delivery systems

Dense breasts and benign breast disease associated with elevated risk of breast cancer

Origin, evolution and ecological relationships of yeasts

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