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University of Oxford scientists develop new candidate malaria vaccine

A new candidate malaria vaccine with the potential to neutralise all strains of the most deadly species of malaria parasite has been developed by a team led by scientists at the University of Oxford.

21 Dec 2011

Takeda enters agreement to acquire Intellikine

Takeda Pharmaceutical Company Limited and Intellikine, Inc. today announced that Takeda America Holdings, Inc., a wholly-owned subsidiary of Takeda, and Intellikine, a privately-held company focused on the discovery and development of innovative, small molecule drugs, have entered into an agreement for Takeda America Holdings to acquire Intellikine by cash.

21 Dec 2011

BMDCs can contribute to olfactory neurons through plasticity mechanism

Bone marrow-derived stem cells (BMDCs) have been recognized as a source for transplantation because they can contribute to different cell populations in a variety of organs under both normal and pathological conditions.

20 Dec 2011

Immunosuppressant combination improves survival of human spinal stem cells in ALS rat model

A team of researchers grafting human spinal stem cells into rats modeled with amyotrophic lateral sclerosis (ALS), also known as "Lou Gehrig's Disease," a degenerative, lethal, neuromuscular disease, have tested four different immunosuppressive protocols aimed at determining which regimen improved long-term therapeutic effects.

20 Dec 2011

Cutting cardiac sympathetic nerve may help control heart rhythms

What do sweaty palms and abnormal heart rhythms have in common? Both can be initiated by the nervous system during adrenaline-driven "flight or fight" stress reaction when the body senses danger.

20 Dec 2011

Hebrew University student wins Kaye Innovation Award for anti-cancer therapy

A strategy for inhibiting a protein that is associated with the spread of cancer has won for a Hebrew University of Jerusalem Ph.D. student in chemistry one of this year's Kaye Innovation Awards at the university.

20 Dec 2011

IRSF announces new grants for research into Rett syndrome

The International Rett Syndrome Foundation (IRSF) announced today that it is awarding over $1.5M to support 18 new grants designed to study a variety of diverse topics from basic science and disease pathology to developing treatments and outcome measures for Rett syndrome.

20 Dec 2011

Math model reveals that spatial tissue structure delays tumor formation

Cancer growth normally follows a lengthy period of development. Over the course of time, genetic mutations often accumulate in cells, leading first to pre-cancerous conditions and ultimately to tumour growth. Using a mathematical model, scientists at the Max Planck Institute for Dynamics and Self-Organization in G-ttingen, University of Pennsylvania and University of California San Francisco, have now shown that spatial tissue structure, such as that found in the colon, slows down the accumulation of genetic mutations, thereby delaying the onset of cancer.

20 Dec 2011

Stabilizing mitochondria protects against Parkinson's in a rat model

Stabilizing the cell's power-generating center protects against Parkinson's disease (PD) in a rat model, according to a report published online this week in the Journal of Experimental Medicine.

20 Dec 2011

Blocking EETs may represent novel strategy for cancer therapy

Recent findings in mice suggest that blocking the production of small molecules produced in the body, known as epoxyeicosatrienoic acids (EETs), may represent a novel strategy for treating cancer by eliminating the blood vessels that feed cancer tumors.

20 Dec 2011

Smoking in women associated with skin cancer: Study

A new study has found a link between tobacco use and skin cancer especially in women. The study found that women who had squamous cell skin cancer were more likely to have smoked than those who were free from the disease. And those who smoked at least 20 years were twice as likely to develop squamous cell skin cancer - a less aggressive form of skin cancer as melanoma.

19 Dec 2011

FDA nod for pediatric Berlin heart

The U.S. Food and Drug Administration (FDA) has approved the Berlin Heart for pediatric patients waiting for heart transplants. The ventricular assist device is similar to the one worn by former Vice President Dick Cheney but scaled down in size for children and babies.

19 Dec 2011

Phase I clinical study of Selexys SelG1 for sickle cell disease completed

Selexys Pharmaceuticals announced today that it has completed a Phase I clinical study of its lead compound SelG1, an antibody specific for the pro-inflammatory cell adhesion molecule P-selectin.

19 Dec 2011

Newgen acquires novel oncology development programs from Kanion

NewGen Therapeutics, Inc. today announced the acquisition of three novel oncology development programs from Kanion USA, Inc. and Kanion Pharmaceutical Co., Ltd..

19 Dec 2011

GreatCall launches new app to make medication management easy

GreatCall, Inc., a leader in wireless services that enable people to stay connected, safe and healthy, today announced the immediate availability of its first Android OS application, MedCoach—a new app designed to make medication management easy for everyone.

19 Dec 2011

ALS TDI, Biogen Idec and UCB enter agreement to study anti-CD40L antibody for ALS

The ALS Therapy Development Institute today announced a research agreement with Biogen Idec and UCB Pharma SA to investigate the use of an anti-CD40L antibody as a potential therapy for Amyotrophic Lateral Sclerosis, also known as Lou Gehrig's or Motor Neuron Disease.

19 Dec 2011

New gel could nip Lyme borreliosis infection in the bud

They come out in the spring, and each year they spread further - the ticks. Thirty percent of them transmit borrelia pathogens, the causative agent of Lyme borreliosis that can damage joints and organs.

19 Dec 2011

Soybean compounds can increase effectiveness of radiation treatment for lung cancer

A Wayne State University researcher has shown that compounds found in soybeans can make radiation treatment of lung cancer tumors more effective while helping to preserve normal tissue.

19 Dec 2011

DDC acquires Orchid Cellmark's government paternity business

DDC (DNA Diagnostics Center), one of the largest DNA testing companies in the world, announced today the acquisition of Orchid Cellmark, Inc.'s government paternity business.

19 Dec 2011

arGEN-X to advance SIMPLE Antibody platform for treatment of autoimmune disorders

arGEN-X, a biopharmaceutical company focused on the discovery and development of human monoclonal antibodies from its proprietary SIMPLE Antibody platform, announced today it has received a grant of €1.3 million to further advance its powerful discovery platform for addressing challenging disease targets.

19 Dec 2011