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TSRI scientists identify small subset of immune cells that play major role in development of Crohn's disease

Two-thirds to three-quarters of the estimated 700,000 Americans living with Crohn's disease, an autoimmune condition that can disrupt the entire gastrointestinal tract, will require surgery at some point during their life.

9 Jan 2014

GSK receives FDA approval for combination of Mekinist with Tafinlar for treatment of melanoma

GlaxoSmithKline plc announced today that the U.S. Food and Drug Administration (FDA) has approved Mekinist® (trametinib) for use in combination with Tafinlar® (dabrafenib) for the treatment of patients with unresectable melanoma (melanoma that cannot be removed by surgery) or metastatic melanoma (melanoma which has spread to other parts of the body) with BRAF V600E or V600K mutations.

9 Jan 2014

UMMS assistant professor recognized with Presidential Early Career Award for Scientists and Engineers

University of Massachusetts Medical School Assistant Professor Thomas G. Fazzio, PhD, was recognized as a rising scientific star by President Obama with a Presidential Early Career Award for Scientists and Engineers.

9 Jan 2014

High presence of bacteria linked to early water breaking during pregnancy

A high presence of bacteria at the site where fetal membranes rupture may be the key to understanding why some pregnant women experience their "water breaking" prematurely, researchers at Duke Medicine report.

9 Jan 2014

Researchers use stem cells to study bone disorders from patients afflicted with genetic bone disease

Researchers have developed a new way to study bone disorders and bone growth, using stem cells from patients afflicted with a rare, genetic bone disease.

9 Jan 2014

Montreal researchers identifies two specific key players in growth of GBM

Glioblastoma (GBM) is the most common and deadly form of primary malignant brain cancer accounting for approximately 15% of all brain tumours and occurring mostly in adults between the ages of 45 and 70.

9 Jan 2014

Rexahn Pharmaceuticals initiates RX-3117 Phase Ib trial in cancer patients with solid tumors

Rexahn Pharmaceuticals, Inc. a clinical stage biopharmaceutical company, announced today the initiation of a Phase Ib clinical trial to study the safety and efficacy of RX-3117 in cancer patients with solid tumors.

9 Jan 2014

NYSCF and ISMMS scientists successfully generate stem cell model of familial Alzheimer's disease

Scientists at The New York Stem Cell Foundation Research Institute in collaboration with scientists at the Icahn School of Medicine at Mount Sinai successfully generated a stem cell model of familial Alzheimer's disease.

8 Jan 2014

Hebrew University research could lead to efficient and fast-acting antidepressant drugs

The World health Organization calls depression "the leading cause of disability worldwide," causing more years of disability than cancer, HIV/AIDS, and cardiovascular and respiratory diseases combined.

8 Jan 2014

C. parvum and cryptosporidiosis: an interview with Dr. Momar Ndao, McGill University

Cryptosporidium parvum is one of the most common enteropathogens to affect humans in the world. The protozoan parasite causes a gut infection referred to as cryptosporidiosis.

8 Jan 2014

Immunocore, MedImmune sign oncology research collaboration and licensing agreement

Immunocore Limited, the Oxford-based biotechnology company developing novel biological drugs to treat cancer and viral disease, today announced that it has entered into an oncology research collaboration and licensing agreement with MedImmune, the global biologics research and development arm of AstraZeneca. Both companies will research and develop novel cancer therapies using Immunocore’s Immune Mobilising Monoclonal T-Cell Receptor Against Cancer technology.

8 Jan 2014

Emmaus completes all patient visits for Phase 3 trial of L-glutamine for treatment of sickle cell disease

Emmaus Medical, Inc., a biopharmaceutical company engaged in the discovery, development and commercialization of innovative and cost-effective treatments and therapies primarily for rare and orphan diseases, today announced it has completed all patient visits for its Phase 3 clinical trial for the treatment of sickle cell disease. Emmaus expects top-line data from the Phase 3 clinical trial to be available in the first quarter of 2014.

8 Jan 2014

Study compares relative rate of molecular evolution between humans and chimps with their lice

A new study compares the relative rate of molecular evolution between humans and chimps with that of their lice. The researchers wanted to know whether evolution marches on at a steady pace in all creatures or if subtle changes in genes - substitutions of individual letters of the genetic code - occur more rapidly in some groups than in others.

8 Jan 2014

IDMC recommends early stopping of Phase 3 study of ibrutinib in treatment of CLL/SLL

Janssen-Cilag International NV today announced the early stopping of PCYC-1112-CA, the Phase 3 study of ibrutinib in the treatment of Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, based on the recommendation of an Independent Data Monitoring Committee, which concluded that the study showed a significant difference in progression-free survival as compared to the control, the primary endpoint of the study.

8 Jan 2014

StemGenex offers stem cell treatment studies to patients diagnosed with diabetes, neurological diseases

According to The American Diabetes Association there are over 25 million people in the US living with diabetes. These patients are suffering from complications such as heart disease, stroke, high blood pressure, blindness, kidney disease, neuropathy and amputation.

8 Jan 2014

Cancer Treatment Centers of America recognized with Clinical Nutrition Team of Distinction Award

Cancer Treatment Centers of America has been recognized by the American Society for Parenteral and Enteral Nutrition with the organization's "Clinical Nutrition Team of Distinction Award". Members of the CTCA professional staff will be honored by A.S.P.E.N at its Clinical Nutrition Week Conference in Savannah, GA this January 2014. This award is presented to multi-discipline clinical teams that exemplify excellence in interdisciplinary clinical nutrition practice in compliance with A.S.P.E.N. standards, guidelines and values.

8 Jan 2014

Professor receives ALSF grant to develop cancer vaccine technology that help children to have healthy life

In 2004, a form of cancer known as neuroblastoma claimed the life of Alexandra (Alex) Scott, a little girl who gained national attention for using her lemonade stand to raise money for cancer research.

8 Jan 2014

Analog Devices unveils high-precision meter-on-a-chip for different portable health applications

Analog Devices, Inc. unveiled today a high-precision, low-power meter-on-a-chip for a range of portable health applications such as point-of-care diagnostics, home/self-test health devices, and wearable vital signs monitors, including those for sports and fitness.

8 Jan 2014

Insight Genetics receives $1.5M SBIR contract to research on resistance mutations in NSCLC patients

Insight Genetics, Inc. today announced it has received a new $1.5 million Phase II Small Business Innovation Research contract from the National Cancer Institute.

8 Jan 2014

CytoDyn receives FDA approval to start Phase 2b study of PRO 140 for treatment of HIV-1

CytoDyn Inc., a biotechnology company focused on the development of new therapies for combating infection with immune deficiency viruses, announced today the Company has received approval from the United States Food and Drug Administration (FDA) to commence patient screening of a Phase 2b study of PRO 140, a monoclonal CCR5 antibody, for the treatment of patients with Human Immunodeficiency Virus Type 1.

8 Jan 2014

Cell News and Research

TSRI scientists identify small subset of immune cells that play major role in development of Crohn's disease

GSK receives FDA approval for combination of Mekinist with Tafinlar for treatment of melanoma

UMMS assistant professor recognized with Presidential Early Career Award for Scientists and Engineers

High presence of bacteria linked to early water breaking during pregnancy

Researchers use stem cells to study bone disorders from patients afflicted with genetic bone disease

Montreal researchers identifies two specific key players in growth of GBM

Rexahn Pharmaceuticals initiates RX-3117 Phase Ib trial in cancer patients with solid tumors

NYSCF and ISMMS scientists successfully generate stem cell model of familial Alzheimer's disease

Hebrew University research could lead to efficient and fast-acting antidepressant drugs

C. parvum and cryptosporidiosis: an interview with Dr. Momar Ndao, McGill University

Immunocore, MedImmune sign oncology research collaboration and licensing agreement

Emmaus completes all patient visits for Phase 3 trial of L-glutamine for treatment of sickle cell disease

Study compares relative rate of molecular evolution between humans and chimps with their lice

IDMC recommends early stopping of Phase 3 study of ibrutinib in treatment of CLL/SLL

StemGenex offers stem cell treatment studies to patients diagnosed with diabetes, neurological diseases

Cancer Treatment Centers of America recognized with Clinical Nutrition Team of Distinction Award

Professor receives ALSF grant to develop cancer vaccine technology that help children to have healthy life

Analog Devices unveils high-precision meter-on-a-chip for different portable health applications

Insight Genetics receives $1.5M SBIR contract to research on resistance mutations in NSCLC patients

CytoDyn receives FDA approval to start Phase 2b study of PRO 140 for treatment of HIV-1

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