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MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

About one-fifth of often deadly head and neck cancers harbor genetic mutations in a pathway that is key to normal cell growth, and scientists report those mutations, which enable abnormal cancer cell growth, can also make the cancer vulnerable.

28 Apr 2022

Researchers unravel why neuropsychiatric symptoms appear in Alzheimer's patients before memory loss

Researchers from Indiana University School of Medicine are studying why neuropsychiatric symptoms, such as apathy and irritability, appear in most Alzheimer's disease patients before the onset of memory loss.

28 Apr 2022

Excess all-cause deaths during the COVID pandemic in the US

In a recent study posted to the medRxiv* preprint server, researchers evaluated excess all-cause mortality, including deaths due to coronavirus disease 2019 (COVID-19) across the United States.

27 Apr 2022

Low dose aspirin is downgraded for preventing cardiovascular disease

A recent article posted in the Journal of the American Medical Association (JAMA) analyzed aspirin use to prevent cardiovascular disease (CVD) and colorectal cancer (CRC).

27 Apr 2022

Green tea catechin as pan-coronavirus attachment inhibitor

In a recent study posted to the Research Square* preprint server, researchers assessed the impact of green tea catechin epigallocatechin gallate (EGCG) on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

27 Apr 2022

Synthetic data accurately replicates the results of analyses from real COVID-19 patient data

Research led by Washington University School of Medicine in St. Louis has demonstrated that analyzing synthetic data generated from real COVID-19 patients accurately replicates the results of the same analyses conducted on the real patient data.

27 Apr 2022

Study uses Twitter posts to examine public attitudes toward COVID-19 vaccination

A new study from the University of Illinois Chicago examines key themes and topics from almost three million COVID-19 vaccine-related tweets posted by individuals and explores the trends and variations in public opinions and sentiments about vaccines and vaccination programs.

27 Apr 2022

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

A plant virus that infects legumes, called cowpea mosaic virus, has a special power that you may not have known about: when injected into a tumor, it triggers the immune system to treat the cancer - even metastatic cancer - and prevents it from recurring.

27 Apr 2022

Novel plug-and-play multi-organ chip can be customized to the patient

Engineered tissues have become a critical component for modeling diseases and testing the efficacy and safety of drugs in a human context.

27 Apr 2022

Researchers show how chronic pain leads to maladaptive anxiety in mice

Hokkaido University researchers have shown how chronic pain leads to maladaptive anxiety in mice, with implications for treatment of chronic pain-related psychiatric disorders in humans.

27 Apr 2022

Research reveals a therapeutic opportunity to prevent rhabdomyosarcoma recurrence

Rhabdomyosarcoma is a type of soft tissue cancer. Scientists at St. Jude Children's Research Hospital studied the population of cells that persists after therapy, causing rhabdomyosarcoma recurrence.

27 Apr 2022

New insights could lead to better treatments for Dravet syndrome and related conditions

Children with Dravet syndrome, a severe form of epilepsy that begins in infancy, experience seizures, usually for their entire life.

27 Apr 2022

Misexpression of non-cardiac genes may lead to congenital heart disease

Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA – a crucial regulatory step before proteins are created. Then, organs develop and hopefully function properly.

27 Apr 2022

Researchers use a systems biology approach to parse the genetic diversity of C. difficile

Researchers at University of California San Diego School of Medicine and Jacobs School of Engineering, with colleagues at Baylor College of Medicine, have used a systems biology approach to parse the genetic diversity of Clostridioides difficile, a particularly problematic pathogen in health care settings.

27 Apr 2022

Study examines whether having MS plays a role in regular cancer screenings and diagnosis

Women with multiple sclerosis (MS) are less likely to have breast cancers detected through cancer screenings than women without MS, according to new research published in the April 27, 2022, online issue of Neurology, the medical journal of the American Academy of Neurology.

27 Apr 2022

Prevalence of multiple sclerosis in Black and white people is similarly high, study says

The rate of multiple sclerosis (MS) cases varies greatly by race and ethnicity. A new study suggests that the prevalence of MS in Black and white people is similarly high, while much lower in Hispanic and Asian people.

27 Apr 2022

Combination therapy shows promise for treating triple-negative breast cancer

Researchers at Baylor College of Medicine and collaborating institutions have identified a combination therapy for treating triple-negative breast cancer (TNBC) that results in durable tumor regression in an animal model of the condition.

27 Apr 2022

New insight into the body’s response to tuberculosis may help design a more effective vaccine

More than 1.7 billion people - or a quarter of the world's population - are infected with Mycobacterium tuberculosis, the bacterial strain that causes tuberculosis (TB).

27 Apr 2022

New findings show rise in racial disparities as availability of proton beam therapy increased in the U.S.

Two new large studies led by researchers at the American Cancer Society (ACS) show an increase in the use of proton beam therapy (PBT) for patients with cancer in the United States during the past decade.

27 Apr 2022

Adult vaccination rates and social determinants of health influenced children’s mental health during pandemic

Adult vaccination rates and social determinants of health - or the social and economic conditions in which families live and work - have played an important role in children's mental health during the pandemic, according to a new study led by Weill Cornell Medicine investigators.

27 Apr 2022

Research News and Research

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

Researchers unravel why neuropsychiatric symptoms appear in Alzheimer's patients before memory loss

Excess all-cause deaths during the COVID pandemic in the US

Low dose aspirin is downgraded for preventing cardiovascular disease

Green tea catechin as pan-coronavirus attachment inhibitor

Synthetic data accurately replicates the results of analyses from real COVID-19 patient data

Study uses Twitter posts to examine public attitudes toward COVID-19 vaccination

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

Novel plug-and-play multi-organ chip can be customized to the patient

Researchers show how chronic pain leads to maladaptive anxiety in mice

Research reveals a therapeutic opportunity to prevent rhabdomyosarcoma recurrence

New insights could lead to better treatments for Dravet syndrome and related conditions

Misexpression of non-cardiac genes may lead to congenital heart disease

Researchers use a systems biology approach to parse the genetic diversity of C. difficile

Study examines whether having MS plays a role in regular cancer screenings and diagnosis

Prevalence of multiple sclerosis in Black and white people is similarly high, study says

Combination therapy shows promise for treating triple-negative breast cancer

New insight into the body’s response to tuberculosis may help design a more effective vaccine

New findings show rise in racial disparities as availability of proton beam therapy increased in the U.S.

Adult vaccination rates and social determinants of health influenced children’s mental health during pandemic

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