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e-Therapeutics announces continuation of ETS2101 phase I trial in brain cancer

e-Therapeutics plc today announces that the investigator-led phase I trial of ETS2101 in brain cancer will continue into 2014. Five dose escalation steps have been completed without any drug-related serious adverse events and the investigator therefore intends to enrol further patients at higher dose levels.

7 Jan 2014

DePuy Synthes develops CONFORM SHEET allograft implant for spinal fusion surgery

DePuy Synthes Spine, in collaboration with DePuy Synthes Biomaterials, announced today the U.S. launch of CONFORM SHEET™, a hydrated, pliable and totally demineralized cancellous bone matrix that fills voids during posterolateral spinal fusion surgery and provides a natural scaffold for new bone formation.

7 Jan 2014

New guidelines provide screening recommendations for people at higher risk of developing lung cancer

Alarmingly, more than 200,000 Americans will be diagnosed with lung cancer this year and nearly 160,000 people will die of the disease. In fact, according to the American Cancer Society, lung cancer takes more lives each year than colorectal, breast and prostate cancers combined.

7 Jan 2014

Cancer cells less likely to develop resistance when multiple drugs delivered simultaneously

Researchers have developed a technique for creating nanoparticles that carry two different cancer-killing drugs into the body and deliver those drugs to separate parts of the cancer cell where they will be most effective. The technique was developed by researchers at North Carolina State University and the University of North Carolina at Chapel Hill.

7 Jan 2014

Study quantifies photoactivation efficiency of fluorescent proteins

To know how many proteins assemble together at the nanoscale is fundamental for understanding protein function. Sometimes, proteins must be in an "oligomeric" state to be functional, although "oligomerization" of certain proteins can also lead to diseases. The ability to determine protein stoichiometry and monitor changes in the balance between monomeric, dimeric and multi-meric proteins can allow scientists to see the differences between a properly functioning cell and a diseased cell. Therefore, there is a great interest in being able to count proteins and determine their stoichiometry.

7 Jan 2014

Researchers work on alternative therapy to boost immune system of patients with lung cancer

Research from the National Institute of Respiratory Diseases informs that besides smoking, there are other factors associated to the development of lung cancer such as the smoke from burning lumber and coal, as well as pollutant particles.

7 Jan 2014

Researchers receive $540M from Ludwig Cancer Research to accelerate research on metastasis

Cancer researchers at the University of Chicago and five other leading institutions will share equally in a $540 million gift from Ludwig Cancer Research, on behalf of its founder Daniel K. Ludwig. Ludwig Cancer Research is an international community of researchers dedicated to pursuing life-changing discoveries to alter the course of cancer.

7 Jan 2014

Study examine effect of high out-of-pocket drug costs for targeted cancer therapies on patients

The cost of insurance co-payments for cutting-edge pharmaceuticals can vary widely from patient to patient. When the patient's share of prescription costs becomes too high, many patients skip doses or stop taking medication entirely, according to research conducted at the University of North Carolina.

6 Jan 2014

Protein may be major culprit when breast cancer metastasizes to the brain

A cancer-research team at the University of Wisconsin-Madison has identified a protein that may be a major culprit when breast cancer metastasizes to the brain.

6 Jan 2014

Adenosine deaminase has potential to improve prognosis, diagnosis and treatment of ESCC

Esophageal Squamous Cell Carcinoma (ESCC), the major histological form of esophageal cancer, is the leading cause of cancer death worldwide. Scientists from the National University of Singapore (NUS) have discovered a biomarker, called adenosine deaminase acting on RNA-1 (ADAR1), which has the potential to improve the diagnosis, prognosis and treatment of this disease.

6 Jan 2014

New approach aims to prevent brain cancer recurrence by attacking tumors at the source

Researchers at the Cedars-Sinai Maxine Dunitz Neurosurgical Institute and Department of Neurosurgery identified immune system targets on cancer stem cells - cells from which malignant brain tumors are believed to originate and regenerate - and created an experimental vaccine to attack them.

6 Jan 2014

Researchers hope to improve treatment, survival rates of ischemic heart disease

Researchers at Case Western Reserve University and University Hospitals Case Medical Center hope to improve treatment and survival rates of ischemic heart disease patients by providing doctors an unprecedented look at the stents they place in coronary arteries.

6 Jan 2014

Stephen J. Teach receives $2.2M award to study how cell phones help manage asthma in children

Stephen J. Teach, MD, MPH, Associate Chief of Emergency Medicine at Children's National Health System, says that aggressively managing parental stress and using cell phone apps to monitor medication usage in at-risk youth with asthma may improve children's adherence to asthma medications.

6 Jan 2014

Portage acquires approximately 54% equity in Biohaven

Portage Biotech Inc., is pleased to announce that it has acquired approximately 54% equity in Biohaven Pharmaceutical Holding Company Limited, a private corporation formed under the laws of the British Virgin Islands, for $3.5 million, payable as $1.75 million upfront and the balance in three installments over the next eleven months.

6 Jan 2014

Thermo Fisher Scientific agrees to sell three businesses to GE Healthcare for $1.06 billion

Thermo Fisher Scientific, the world leader in serving science, today announced that it has signed an agreement to sell its cell culture (sera and media), gene modulation and magnetic beads businesses to GE Healthcare, a unit of General Electric Company, for approximately $1.06 billion. The businesses will become part of GE Healthcare's Life Sciences division.

6 Jan 2014

Cord Blood America achieves AABB accreditation for cell therapy activity

Cord Blood America, Inc. today announced it has achieved AABB accreditation for cell therapy activity associated with cord blood processing, storage and distribution.

6 Jan 2014

BioLife Solutions announces preliminary revenue of $9 million for 2013

BioLife Solutions, Inc., a leading developer, manufacturer and marketer of proprietary clinical-grade hypothermic storage and cryopreservation freeze media and precision thermal shipping products for cells and tissues, today announced preliminary revenue of $9.0 million for the full year 2013.

6 Jan 2014

FDA grants orphan drug designation for DiaVacs' type 1 diabetes mellitus therapy

DiaVacs, Inc. announced today that the Office of Orphan Products Development of the Food and Drug Administration has granted orphan drug designation for the company's type 1 diabetes mellitus (T1DM) therapy.

6 Jan 2014

Editing of protein-making sequences promotes development of ESCC, find NUS researchers

Esophageal Squamous Cell Carcinoma, the major histological form of esophageal cancer, is the leading cause of cancer death worldwide. Scientists from the National University of Singapore have discovered a biomarker, called adenosine deaminase acting on RNA-1, which has the potential to improve the diagnosis, prognosis and treatment of this disease.

6 Jan 2014

NICE issues Final Appraisal Determination for PIXUVRI (pixantrone) drug

Cell Therapeutics, Inc. (CTI) (NASDAQ and MTA: CTIC) today reported that the National Institute for Health and Care Excellence (NICE), the independent body responsible for driving improvement and excellence in the health and social care system in the United Kingdom (UK), has issued its Final Appraisal Determination (FAD) for PIXUVRI® (pixantrone).

6 Jan 2014

Cell News and Research

e-Therapeutics announces continuation of ETS2101 phase I trial in brain cancer

DePuy Synthes develops CONFORM SHEET allograft implant for spinal fusion surgery

New guidelines provide screening recommendations for people at higher risk of developing lung cancer

Cancer cells less likely to develop resistance when multiple drugs delivered simultaneously

Study quantifies photoactivation efficiency of fluorescent proteins

Researchers work on alternative therapy to boost immune system of patients with lung cancer

Researchers receive $540M from Ludwig Cancer Research to accelerate research on metastasis

Study examine effect of high out-of-pocket drug costs for targeted cancer therapies on patients

Protein may be major culprit when breast cancer metastasizes to the brain

Adenosine deaminase has potential to improve prognosis, diagnosis and treatment of ESCC

New approach aims to prevent brain cancer recurrence by attacking tumors at the source

Researchers hope to improve treatment, survival rates of ischemic heart disease

Stephen J. Teach receives $2.2M award to study how cell phones help manage asthma in children

Portage acquires approximately 54% equity in Biohaven

Thermo Fisher Scientific agrees to sell three businesses to GE Healthcare for $1.06 billion

Cord Blood America achieves AABB accreditation for cell therapy activity

BioLife Solutions announces preliminary revenue of $9 million for 2013

FDA grants orphan drug designation for DiaVacs' type 1 diabetes mellitus therapy

Editing of protein-making sequences promotes development of ESCC, find NUS researchers

NICE issues Final Appraisal Determination for PIXUVRI (pixantrone) drug

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