Colon News and Research

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High resolution confocal endomicroscopy probe system tells whether colon polyp is benign without removal

A probe so sensitive that it can tell whether or not a cell living within the human body is veering towards cancer development may revolutionize how future colonoscopies are done, say researchers from the Mayo Clinic in Jacksonville, Fla.

21 May 2008

DNA modification seen in colorectal tumors helps predict outcomes, John Wayne Cancer Institute researchers find

An international study led by researchers at the John Wayne Cancer Institute at Saint John's Health Center has found that modifications to DNA found on multiple chromosomes in tumors can help to predict outcomes in patients with early-stage rectal cancer.

21 May 2008

Body mass index in adolescence in relation to cause-specific mortality

People who were already overweight in adolescence (14-19 years old) have an increased mortality rate from a range of chronic diseases as adults; endocrine, nutritional and metabolic diseases, cardiovascular diseases, colon cancer and respiratory diseases. There were also many cases of sudden death in this group. This comes from a new study from the Norwegian Institute of Public Health (NIPH).

20 May 2008

New Wilmot Cancer Center offers expanded care, research for cures

The University of Rochester Medical Center (URMC) today celebrates the expansion of cancer care and research as it dedicates the new James P. Wilmot Cancer Center. The Center introduces leading-edge technology, greater access to multidisciplinary care, a new model for breast care, and more opportunities to receive tomorrow's therapies today.

15 May 2008

Discovery of new gene that causes cancer

Researchers at the OU Cancer Institute have identified a new gene that causes cancer. The ground-breaking research appears in Nature's cancer journal Oncogene.

8 May 2008

Whole-organ genomic survey depicts journey from normal to malignant cell

Whole-organ maps that superimpose genetic information over the terrain of cancerous bladders chart the molecular journey from normal cell to invasive cancer, an international research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports online at the journal Laboratory Investigation.

5 May 2008

New understanding of colon tumor development

Recent work from the Finnish Academy Center of Excellence on Cancer Biology at the University of Helsinki, Finland, has shed light on the mechanisms of colon tumor development and may help to design better treatment for this disease.

5 May 2008

Epidermal growth factor receptor protects cancer cells from starving

A growth factor receptor found abundantly on the surface of cancer cells and long known to fuel cancer growth also protects tumor cells from starvation by a newly identified mechanism, researchers at The University of Texas M. D. Anderson Cancer Center report in the May 5 issue of Cancer Cell.

5 May 2008

AMPK signaling helps explain how cell growth is inhibited when nutrients are low

A team of scientists at the Salk Institute for Biological Studies think they know how many-if not most-living organisms answer this question. They recently showed that when food supplies dwindle, mammals, fruitflies, or frogs probably activate the same ancient cell signaling pathway in order to conserve energy.

24 Apr 2008

Competency in colonoscopy requires experience with 150 cases or more

Researchers from Korea have found that technically efficient screening and diagnostic colonoscopy generally requires experience with 150 cases or more.

23 Apr 2008

Discovery of new cell targets for preventing growth of breast and other tumors

Researchers at the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have discovered new targets for cancer treatment aimed at blocking a key step in tumor progression.

23 Apr 2008

MacroChem acquires Virium Pharmaceuticals

MacroChem Corporation announced today that on April 18, 2008 it acquired Virium Pharmaceuticals Inc., a non-public, development stage company developing and commercializing novel therapeutics, with a portfolio of clinical stage product candidates focused in oncology, including its next generation nucleoside analogue licensed from the Southern Research Institute.

23 Apr 2008

Cisplatin found to be less effective than standard treatment for patients with anal cancer

When administered before chemoradiation, the common anti-cancer drug cisplatin neither improved disease-free survival nor reduced the number of colostomies needed when compared to the standard treatment for patients with anal canal cancer, according to a study published in the April 23 issue of the JAMA, the Journal of the American Medical Association.

22 Apr 2008

Chemotherapy causes delayed severe neural damage

Cancer treatment with chemotherapeutic agents is often associated with delayed adverse neurological consequences - an occurrence often referred to as "chemobrain" - that may compromise the quality of life of a proportion of cancer survivors.

21 Apr 2008

The limits of observational data in determining outcomes from cancer therapy

Certain biases may exist in observational studies that compare outcomes of different cancer therapies, making the results questionable.

21 Apr 2008

Hypertension all about what you eat and drink

Scientific research on human metabolism based on people from around the world has revealed compounds in urine indicate surprising differences affecting blood pressure.

20 Apr 2008

Inherited cancer gene mutation more common than formerly believed

A gene mutation responsible for the most common form of inherited colon cancer is older and more common than formerly believed, according to a recent study.

17 Apr 2008

New type of drug shrinks primary breast cancer tumours significantly in just six weeks

A drug that targets the cell surface receptors that play an important role in many types of cancer can bring about significant tumour regression in breast cancer after only six weeks of use, a scientist told the 6th European Breast Cancer Conference (EBCC-6) (Thursday 17 April).

17 Apr 2008

Wild Mediterranean plant provides potential anticancer medicines

A group of scientists from the Department of Organic Chemistry and the Biotechnology Institute of the University of Granada have found out that the plant “Dittirichia viscose”, known as elecampe, can be used to obtain inhibitors of neurogenic vasodilatation, a significant progress in migraine and cancer treatments.

17 Apr 2008

An effective colon cancer prevention treatment

Using a combination of a targeted cancer-fighting agent called DFMO and a low dose of an anti-inflammatory drug, UC Irvine researchers have reduced the risk of reoccurring colorectal polyps, an early sign of colon cancer, by as much as 95 percent with fewer toxic side effects.

15 Apr 2008