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Benefit of using antibody-coated drug-eluting stents for CHD still unclear, shows report

In patients with coronary heart disease requiring a stent implantation, the benefit of treatment with antibody-coated drug-eluting stents (ABC-DES) versus drug-eluting stents without antibody coating (DES) is still unclear.

17 Feb 2016

New study could help explain critical shortcomings in stem cell-driven therapies for heart disease

With every heart attack, billions of cardiomyocytes, the contracting heart muscle cells that make the heart pump time after time over a lifetime, are lost which can lead to heart failure or injury. Stem cell-based replacement strategies could open new and much needed therapeutic avenues.

17 Feb 2016

MemorialCare partners with Fresenius Medical Care to operate 15 dialysis clinics in Southern California

MemorialCare Health System announced today that it has entered into a joint venture partnership with Fresenius Medical Care North America to operate 15 dialysis clinics in Orange and Los Angeles counties. Thirteen of these clinics are fully operational and two additional clinics are being developed in San Juan Capistrano and Huntington Beach.

17 Feb 2016

Vascular surgery safer than stenting for older patients with carotid stenosis

Vascular surgery appears to be safer than stenting for patients over 70 years of age with carotid stenosis, or a blockage of the carotid arteries in the neck, according to new findings published today in the Lancet.

16 Feb 2016

Researchers identify how Toxoplasma parasite crosses blood-brain barrier

An estimated 30 percent of the world's population is chronically infected with the parasite Toxoplasma gondii. Most people live with the infection without noticeable effect, but it can be life-threatening for people with suppressed immune systems, such as people on cancer therapies or who have HIV/AIDS.

16 Feb 2016

Variations in Tie2 gene play significant role in patient responses to infections

Major infections such as influenza and bacterial sepsis kill millions of people each year, often resulting fro dangerous complications that impair the body's blood vessels. But the reasons why some patients experience these dramatic responses to infections -- and others don't -- have been unclear.

16 Feb 2016

Atypical heart attack symptoms lead to delayed treatment, increased injury in women

When having a heart attack, most people will experience some kind of chest pain or pressure that worsens. Pain and pressure, along with sweating, shortness of breath and pain that migrates into the arms or neck are the typical heart attack symptoms.

12 Feb 2016

Scientists find that daily dose of beetroot juice significantly improves exercise endurance, blood pressure

Scientists at Wake Forest Baptist Medical Center have found that a daily dose of beetroot juice significantly improved exercise endurance and blood pressure in elderly patients with heart failure with preserved ejection fraction (HFPEF).

11 Feb 2016

CHLA researchers develop novel model for studying neonatal lung disorder

Investigators at The Saban Research Institute of Children's Hospital Los Angeles have created a novel model for studying a lung disorder of newborn babies. Their study, published in PLOS ONE on February 10, describes the first model that allows investigators to consider the chronic effects of developmental lung disease.

11 Feb 2016

Study finds significant variation in dementia incidence among ethnic and racial groups

In the largest and longest study thus far of ethnic disparities in dementia risk, researchers compared six ethnic and racial groups within the same geographic population and found significant variation in dementia incidence among them.

11 Feb 2016

Researchers devise lipid-based diets to relieve symptoms of Alzheimer's disease

Alzheimer´s disease (AD) is the most common disease underlying memory problems and dementia in the elderly. One of the invariable pathologies in AD is degeneration of cholinergic synapses in brain cortex and hippocampus.

11 Feb 2016

EndoChoice Holdings releases Lumos Adaptive Matrix Imaging system

EndoChoice Holdings, Inc. announced the release of Lumos, a novel and proprietary imaging software system as part of the Fuse Full Spectrum Endoscopy platform. Scientists and engineers at EndoChoice created Lumos based upon Adaptive Matrix Imaging which analyzes and selectively enhances the vascularity, surface texture, and color of abnormal tissue, providing better clarity for physicians.

11 Feb 2016

Dementia incidence highest in African Americans, lowest in Asian Americans

The first study to look at dementia risk in a population representing the diversity of the United States finds dementia incidence to be highest in African Americans and lowest in Asian Americans. The rate of occurrence of dementia in African Americans was found to be 65 percent higher than Asian Americans.

10 Feb 2016

Vanderbilt researchers use cotton candy machines to produce artificial capillary system

For several years, Leon Bellan, assistant professor of mechanical engineering at Vanderbilt University, has been tinkering with cotton candy machines, getting them to spin out networks of tiny threads comparable in size, density and complexity to the patterns formed by capillaries - the tiny, thin-walled vessels that deliver oxygen and nutrients to cells and carry away waste.

9 Feb 2016

Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

Researchers have new insight into the complex interchange that can raise blood levels of unhealthy lipids, or fat, in type 1 diabetes, and early evidence that a drug under study to block cancer cell growth can restore healthier levels.

8 Feb 2016

Incidence and severity emerging CVD risk factors may differ between genders

The incidence and severity of both traditional and emerging cardiovascular disease (CVD) risk factors as well as the response to treatment may differ between genders. In this narrative review, several emerging CVD risk factors (i.e. inflammatory and haemostatic markers, endothelial dysfunction, homocysteine, lipid disorders, microalbuminuria/proteinuria, coronary artery calcium score, arterial stiffness, periodontitis, inflammatory bowel syndrome, obstructive sleep apnea, impaired glucose metabolism, metabolic syndrome and non-alcoholic fatty liver disease) are discussed in the context of gender differences.

5 Feb 2016

BMPR2 mutations affect outcomes of PAH patients

Mutations in the bone morphogenetic protein receptor type II gene affect not only the risk of developing pulmonary arterial hypertension but also the severity and outcomes of the disease, shows a meta-analysis of individual patient data.

4 Feb 2016

Combined MRI and ultramicroscopy toolkit could help study vessel growth in glioma models in more detail

Stopping the growth of blood vessels in tumours is a key target for glioblastoma therapies, and imaging methods are essential for initial diagnosis and monitoring the effects of treatments. While mapping vessels in tumours has proven a challenge, researchers have now developed a combined magnetic resonance imaging (MRI) and ultramicroscopy 'toolkit' to study vessel growth in glioma models in more detail than previously possible.

3 Feb 2016

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

RNA is becoming an interesting drug target as it takes possible intervention back one step to the synthesis of a target protein, instead of trying to block or inhibit a process.

1 Feb 2016

Researchers develop new sensor for continuous monitoring of blood flow in vascular diseases patients

Frequent measurement of blood flow changes could improve the ability of health care providers to diagnose and treat patients with vascular conditions, such as those associated with diabetes and high blood pressure.

30 Jan 2016

Vascular News and Research

Benefit of using antibody-coated drug-eluting stents for CHD still unclear, shows report

New study could help explain critical shortcomings in stem cell-driven therapies for heart disease

MemorialCare partners with Fresenius Medical Care to operate 15 dialysis clinics in Southern California

Vascular surgery safer than stenting for older patients with carotid stenosis

Researchers identify how Toxoplasma parasite crosses blood-brain barrier

Variations in Tie2 gene play significant role in patient responses to infections

Atypical heart attack symptoms lead to delayed treatment, increased injury in women

Scientists find that daily dose of beetroot juice significantly improves exercise endurance, blood pressure

CHLA researchers develop novel model for studying neonatal lung disorder

Study finds significant variation in dementia incidence among ethnic and racial groups

Researchers devise lipid-based diets to relieve symptoms of Alzheimer's disease

EndoChoice Holdings releases Lumos Adaptive Matrix Imaging system

Dementia incidence highest in African Americans, lowest in Asian Americans

Vanderbilt researchers use cotton candy machines to produce artificial capillary system

Study provides new insight into complex interchange that can raise blood levels of fat in type 1 diabetes

Incidence and severity emerging CVD risk factors may differ between genders

BMPR2 mutations affect outcomes of PAH patients

Combined MRI and ultramicroscopy toolkit could help study vessel growth in glioma models in more detail

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

Researchers develop new sensor for continuous monitoring of blood flow in vascular diseases patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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