Cell News and Research

RSS

Scientists receive 2013 Louisa Gross Horwitz Prize for advancements in field of neuroscience

For discoveries about how the brain calculates and remembers where it is—which could be part of the foundation of memory—Columbia University will award the 2013 Louisa Gross Horwitz Prize to Edvard I. Moser, PhD, and May-Britt Moser, PhD, of the Norwegian University of Science and Technology in Norway, and John Michael O'Keefe, PhD, of University College London in the UK.

6 Dec 2013

Combination drug therapy does not work well in clinical trials for cancer patients, say researchers

Medical researchers at the University of Alberta have discovered that combination drug therapy didn't work well in clinical trials for cancer patients because one drug was making the other drug ineffective.

6 Dec 2013

Johns Hopkins researchers discover some cases of scleroderma likely to be initiated by cancer

The Scleroderma Research Foundation today reported that researchers at The Johns Hopkins University have discovered that some cases of scleroderma are likely to have been initiated by cancer.

6 Dec 2013

Researchers produce erythrocyte progenitor cells by transducing two genes into iPS and ES cells

By transducing two genes (c-MYC and BCL-XL) into iPS cells and ES cells, a Kyoto University research team led by Prof. Koji Eto at CiRA has succeeded in producing erythrocyte progenitor cells with almost unlimited ability to replicate in vitro, which they then differentiated successfully into mature erythrocytes. Although these erythrocytes consisted mostly of fetal-type hemoglobin, they were confirmed to have oxygen-carrying capacity and to have circulatory capacity following transfusion into mice.

6 Dec 2013

Scientists identify key factor for limiting inflammatory responses, particularly in skin

Sanford-Burnham scientists have identified the B and T Lymphocyte Attenuator (BTLA) inhibitory receptor as a key factor in limiting inflammatory responses, particularly in the skin. The study, published online today in Immunity, provides clarity on how T cells get fired up to protect against pathogens, and then cool down to restore immune homeostasis.

6 Dec 2013

Telomerase inhibiting drug induces morphologic, molecular, clinical remissions in myelofibrosis patients

metelstat, a novel telomerase inhibiting drug, has been found to induce morphologic, molecular and clinical remissions in some patients with myelofibrosis a Mayo Clinic study has found. The results were presented today at the 2013 American Society of Hematology Annual Meeting in New Orleans.

6 Dec 2013

Researchers identify biomarker that may accurately predict prostate cancer spread

Researchers at Vanderbilt University Medical Center and the University of Alberta in Canada have identified a biomarker for a cellular switch that accurately predicts which prostate cancer patients are likely to have their cancer recur or spread.

6 Dec 2013

Tel Aviv University says caffeine and alcohol can change part of DNA linked to aging, cancer

Coffee and beer are polar opposites in the beverage world. Coffee picks you up, and beer winds you down.

6 Dec 2013

Cancer triggers scleroderma, shows evidence

Johns Hopkins scientists have found evidence that cancer triggers the autoimmune disease scleroderma, which causes thickening and hardening of the skin and widespread organ damage.

6 Dec 2013

Manipulation of Wnt/B-catenin pathway provides therapeutic targets for hair loss, skin cancer

A pathway known for its role in regulating adult stem cells has been shown to be important for hair follicle proliferation, but contrary to previous studies, is not required within hair follicle stem cells for their survival, according to researchers with the Perelman School of Medicine at the University of Pennsylvania.

5 Dec 2013

Researchers identify gene involved in building circuitry that relays signals via brain

Using a powerful gene-hunting technique for the first time in mammalian brain cells, researchers at Johns Hopkins report they have identified a gene involved in building the circuitry that relays signals through the brain.

5 Dec 2013

Training advised to plug lung cancer care gaps

Guideline-consistent care for patients with suspected lung cancer with mediastinal lymphadenopathy without distant metastases varies by region and physician characteristics, say researchers.

5 Dec 2013

Genocea commences GEN-004 Phase 1 study to prevent pneumococcus infections

Genocea Biosciences, Inc., a clinical-stage company pioneering novel T cell vaccines, announced today that it has initiated a Phase 1 study of GEN-004, an investigational vaccine candidate for pneumococcus (Streptococcus pneumoniae), a major cause of infectious disease-related death globally. GEN-004 is the first vaccine candidate designed to prevent infections caused by all strains of pneumococcus through a novel T cell-mediated mechanism of action.

5 Dec 2013

Soligenix initiates SGX942 Phase 2 study for treatment of oral mucositis

Soligenix, Inc., a clinical stage biopharmaceutical company focused on developing products to treat serious inflammatory diseases where there remains an unmet medical need, as well as developing several biodefense vaccines and therapeutics, announced today that it has initiated a Phase 2, randomized, double-blind, placebo-controlled study evaluating SGX942, a first-in-class innate defense regulator, as a treatment for oral mucositis in patients undergoing chemoradiation therapy for head and neck cancer.

5 Dec 2013

"Virtual T cell" predicts how human immune system reacts to foreign substances

A platform that simulates how the body defends itself: The T cells of the immune system decide whether to trigger an immune response against foreign substances.

5 Dec 2013

Researchers find correlation between biomarker and patient’s ability to respond to Imprime PGG

Biothera researchers have broadened their understanding of a biomarker that may enable doctors to predict which cancer patients will best respond to Imprime PGG®, the company's immunotherapy in Phase 3 drug development for colorectal cancer.

5 Dec 2013

Elsevier strengthens long-standing relationship with China Science Publishing & Media

Elsevier, a world-leading provider of scientific, technical and medical (STM) information products and services, and part of the Reed Elsevier group, announced today that it is strengthening and refocusing the scope of its long-standing relationship with China Science Publishing & Media Ltd. (CSPM) to create an international publishing platform for English-language STM journals that brings the expanding wealth of research originating from China to the world.

5 Dec 2013

Findings suggest new approach for treating inflammatory bone diseases and skeletal metastases

The skeleton is constantly being remodelled by the breakdown of old bone by cells called osteoclasts and the formation of new bone by cells called osteoblasts. This coordinated activity is essential for maintaining healthy bone. However, excessive osteoclast activity leads to bone destruction in skeletal diseases such as osteoporosis, rheumatoid arthritis and cancer metastases in bone. A family of signaling enzymes known as phosphatidylinositol 3-kinases control diverse cell functions but, up until now, little was known about the function of specific PI3K isoforms in osteoclasts.

5 Dec 2013

Biologists discover how nerve cells recycle tiny vesicles

University of Utah and German biologists discovered how nerve cells recycle tiny bubbles or "vesicles" that send chemical nerve signals from one cell to the next. The process is much faster and different than two previously proposed mechanisms for recycling the bubbles.

5 Dec 2013

New report analyzes growth and development of stem cell field

Elsevier, EuroStemCell, and Kyoto University's Institute for Integrated Cell-Material Sciences, today released "Stem Cell Research report: Trends and Perspectives on the Evolving International Landscape" at the World Stem Cell Summit. This new, comprehensive analysis of the growth and development of the stem cell field as a whole, closely examines the research landscape for embryonic stem cell, human embryonic stem cell and induced pluripotent stem cell.

5 Dec 2013

Cell News and Research

Scientists receive 2013 Louisa Gross Horwitz Prize for advancements in field of neuroscience

Combination drug therapy does not work well in clinical trials for cancer patients, say researchers

Johns Hopkins researchers discover some cases of scleroderma likely to be initiated by cancer

Researchers produce erythrocyte progenitor cells by transducing two genes into iPS and ES cells

Scientists identify key factor for limiting inflammatory responses, particularly in skin

Telomerase inhibiting drug induces morphologic, molecular, clinical remissions in myelofibrosis patients

Researchers identify biomarker that may accurately predict prostate cancer spread

Tel Aviv University says caffeine and alcohol can change part of DNA linked to aging, cancer

Cancer triggers scleroderma, shows evidence

Manipulation of Wnt/B-catenin pathway provides therapeutic targets for hair loss, skin cancer

Researchers identify gene involved in building circuitry that relays signals via brain

Training advised to plug lung cancer care gaps

Genocea commences GEN-004 Phase 1 study to prevent pneumococcus infections

Soligenix initiates SGX942 Phase 2 study for treatment of oral mucositis

"Virtual T cell" predicts how human immune system reacts to foreign substances

Researchers find correlation between biomarker and patient’s ability to respond to Imprime PGG

Elsevier strengthens long-standing relationship with China Science Publishing & Media

Findings suggest new approach for treating inflammatory bone diseases and skeletal metastases

Biologists discover how nerve cells recycle tiny vesicles

New report analyzes growth and development of stem cell field

Improve fermentation and cell culture performance with real-time gas analysis eBook

Latest eBooks

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms