Angiotensin Converting Enzyme 2 News and Research

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Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States described a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) SP1-77 that broadly neutralized its multiple variants of concern (VOCs).

28 Jun 2022

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

Scientists from China have recently deciphered the genetic network and biological mechanisms associated with COVID-19 myocarditis using bioinformatic methods.

28 Jun 2022

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Researchers performed genomic comparisons between alphacoronaviruses (αCoVs) and betacoronaviruses (βCoVs) originating from South Korean Bats.

28 Jun 2022

The potential of DNA-based SARS-CoV-2 vaccine candidates

Researchers evaluated the immunogenicity of DNA-based candidate vaccines against SARS-CoV-2 in mice.

28 Jun 2022

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

A recent study by scientists at Celentyx Ltd, the University of Birmingham, and the University of Warwick and posted to the bioRxiv* preprint server illustrated a cell-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein attachment assay.

28 Jun 2022

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

In a recent article posted to the bioRxiv* preprint server, researchers at Texas Biomedical Research Institute, Georgia State University, and the University of Alabama at Birmingham developed a bireporter-expressing recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) for tracking SARS-CoV-2 infection.

27 Jun 2022

Omicron variant of SARS-CoV-2 leads to less severe disease in mouse models

Georgia State University researchers have found that the Alpha, Beta and Delta variants of SARS-CoV-2 were substantially more fatal in mouse models than the original strain of the virus that causes COVID-19.

27 Jun 2022

Scientists conduct meta-analysis of the impact of SARS-CoV-2 on sperm parameters

Scientists conducted a meta-analysis to study the impacts of COVID-19 on the male reproductive system.

27 Jun 2022

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

Researchers constructed a full-length SARS-CoV-2 spike structure in its membrane-bound state to study functionally relevant aspects of its global conformational dynamics.

27 Jun 2022

The prevalence of long-COVID in children and adolescents

A recent study published in the Scientific Reports journal assessed the incidence of long-coronavirus disease (COVID) among adolescents and children.

27 Jun 2022

Scientists develop suitable human cell line for anti-SARS-CoV-2 drug screening

Scientists have described the development of a modified A549 cell line that shows a robust expression of ACE2 and TMPRSS2 and high susceptibility to SARS-CoV-2 infection.

24 Jun 2022

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

A recent article posted to the bioRxiv* preprint server identified numerous efficacious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from convalescent SARS-CoV-2 patients.

23 Jun 2022

SARS-CoV-2 evades natural killer cell cytotoxic responses

In a recent study posted to the bioRxiv* preprint server, researchers at Stanford University School of Medicine revealed the mechanism via severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escapes natural killer (NK) cell cytotoxic reactions.

22 Jun 2022

Angiotensin Converting Enzyme 2 News and Research

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

The potential of DNA-based SARS-CoV-2 vaccine candidates

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

Omicron variant of SARS-CoV-2 leads to less severe disease in mouse models

Scientists conduct meta-analysis of the impact of SARS-CoV-2 on sperm parameters

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

The prevalence of long-COVID in children and adolescents

Scientists develop suitable human cell line for anti-SARS-CoV-2 drug screening

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

SARS-CoV-2 evades natural killer cell cytotoxic responses

The effect of the COVID-19 BNT162b2 vaccine on semen parameters among semen donors

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

The impact of epistatic interactions on the ACE2 affinity in the SARS-CoV-2 Omicron variant

Study explains the structural basis of higher ACE2 binding affinity of Omicron sub-variants

Researchers investigate COVID fog and chemokine C–C motif ligand 11

Scientists explore effectiveness of neutralizing antibodies against SARS-CoV-2 Omicron variant

Researchers evaluate artemisinin for COVID-19 management

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