Biochemistry News and Research

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KCI announces creation of Advanced Research and Technology center

Kinetic Concepts, Inc. announced today the creation of an Advanced Research and Technology (ART) center that will lead the company's efforts to develop revolutionary new wound healing, regenerative medicine, and therapeutic support system technologies and treatments.

13 Jul 2010

Study identifies protein that turns non-malignant tumor into metastatic neuroendocrine tumor

Some types of prostate tumors are more aggressive and more likely to metastasize than others. Nearly one-third of these aggressive tumors contain a small nest of especially dangerous cells known as neuroendocrine-type cells. More rarely, some aggressive prostate tumors are made up entirely of neuroendocrine-type cells. The presence of neuroendocrine-type cancer cells is associated with a poor prognosis, but spotting these rare cells can be like finding a needle in a haystack.

13 Jul 2010

British Mycological Society announces 'The Biology of Fungi' programme at IMC9

The British Mycological Society, in association with Elsevier, the world-leading publisher of scientific, technical and medical information, today announced the final programme for the 9th Mycological Congress IMC9: The Biology of Fungi. This congress takes place every 4 years at a different venue around the world.

12 Jul 2010

Researchers demonstrate that MSNs can effectively suppress tumors in mice

The application of nanotechnology in the field of drug delivery has attracted much attention in recent years. In cancer research, nanotechnology holds great promise for the development of targeted, localized delivery of anticancer drugs, in which only cancer cells are affected.

12 Jul 2010

Research finding uncovers alternative treatments for people with hereditary colorectal cancer

By solving the three-dimensional structure of a protein involved in repairing DNA errors, a group of McMaster University researchers have revealed new avenues to develop assessment tools and alternative treatments for people living with hereditary colorectal cancers.

9 Jul 2010

IRIC scientists identify vitamin B3 as potential antifungal treatment

A team of scientists from the Institute for Research in Immunology and Cancer (IRIC) of the University of Montreal have identified vitamin B3 as a potential antifungal treatment. Led by IRIC Principal Investigators Martine Raymond, Alain Verreault and Pierre Thibault, in collaboration with Alaka Mullick, from the Biotechnology Research Institute of the National Research Council Canada, the study is the subject of a recent article in Nature Medicine.

9 Jul 2010

Japanese scientists identify long-elusive enzyme necessary for proper regulation of cilia

It's safe to say that cilia, the hairlike appendages jutting out from the smooth surfaces of most mammalian cells, have long been misunderstood - underestimated, even.

8 Jul 2010

Article related to MN-166 mechanism of action included in PNAS USA

MediciNova Inc, a biopharmaceutical company publicly traded on the NASDAQ Global Market and the Hercules Market of the Osaka Securities Exchange (Code Number:4875), today reported that the June 22, 2010 issue of Proceedings of the National Academy of Sciences USA included an article related to the mechanism of action of MN-166 (ibudilast), as an emerging therapeutic for neurological disorders.

8 Jul 2010

PolyMAC technique retrieves specific proteins needed to study formation of cancer cells

A Purdue University researcher can better retrieve specific proteins needed to study how cancer cells form by using a newly developed technique and synthetic nanopolymer.

8 Jul 2010

Silence strengthens RNAi IP portfolio with issuance of key patent in structural modification technology

Silence Therapeutics plc announces the issuance of United States patent 7,750,144, titled Methods and Compositions for Enhancing Efficacy and Specificity of RNA Silencing, by the United States Patent and Trademark Office (USPTO). The issued patent generally claims methods of producing double stranded (RNAi) agents having decreased off-target silencing activity through certain structural modifications. The ability to minimize the off-target effects of RNAi therapeutics is critical for controlling unwanted cellular activity and/or potential safety concerns.

8 Jul 2010

Researchers develop computer program to accurately simulate protein folding

All proteins self-assemble in a fraction of the blink of an eye, but it can take a long time to mimic the process. And there has been no guarantee of success, even with the most powerful computers - until now.

8 Jul 2010

Patent issued for jellyfish protein for therapeutic application

Quincy Bioscience, a research-based biotechnology company, announced the issuance of United States patent No.7,671,015. The patent covers the use of aequorin-containing compounds for the purpose of preventing and alleviating symptoms and disorders related to calcium imbalance.

7 Jul 2010

Map of herpes virus "cell-entry machinery" provides new target for antiviral drugs

The mechanism by which a herpes virus invades cells has remained a mystery to scientists seeking to thwart this family of viruses. New research funded by the National Institutes of Health and published online in advance of print in Nature Structural & Molecular Biology reveals the unusual structure of the protein complex that allows a herpes virus to invade cells. This detailed map of a key piece of the herpes virus "cell-entry machinery" gives scientists a new target for antiviral drugs.

7 Jul 2010

Study finds additional targets for new therapies to treat advanced prostate cancer patients

In its early stages, prostate cancer requires androgens (hormones that promote the development and maintenance of male sex characteristics) for growth, and current first-line therapies target the receptor for these hormones to slow cancer's development and spread.

7 Jul 2010

Antioxidant supplements increase artery elasticity in patients with multiple cardiovascular risk factors

Long-term supplementation with dietary antioxidants has beneficial effects on sugar and fat metabolism, blood pressure and arterial flexibility in patients with multiple cardiovascular risk factors. Researchers writing in BioMed Central's open access journal Nutrition and Metabolism report these positive results in a randomized controlled trial of combined vitamin C, vitamin E, coenzyme Q10 and selenium capsules.

6 Jul 2010

Lensless cell phone microscope

Cell phones are accumulating a Swiss Army Knife-esqe assortment of capabilities; substituting as cameras, providing internet access, and soon operating as medical labs if Aydogan Ozcan's plans come to fruition. This month's cover article of the journal Lab on a Chip features the latest creation by the Ozcan group, a functioning prototype of a cell phone microscope.

1 Jul 2010

FnBP is central to bacteria's ability to invade organs: Researchers

Scientists studying the so-called "superbug" MRSA have identified one of the components responsible for making it so deadly. Staphylococcus aureus is a type of bacteria commonly found on the skin that is relatively harmless unless it gets into the bloodstream, where it can cause blood poisoning and create abscesses in organs such as the heart and brain.

1 Jul 2010

Studies link anti-cholesterol statin drugs to increased risk of anxiety and depression

Scientists are reporting a possible explanation for the symptoms of anxiety and depression that occur in some patients taking the popular statin family of anti-cholesterol drugs, and reported by some individuals on low-cholesterol diets. These symptoms could result from long-term, low levels of cholesterol in the brain, the report suggests. It appears in ACS' weekly journal Biochemistry.

1 Jul 2010

Bortezomib may offer hope for treating inflammatory diseases: New research

Those looking for a new treatment for a range of inflammatory diseases like arthritis, multiple sclerosis, inflammatory bowel disease, and lupus may need to look no further than a drug already available for treating cancer. In a research report published in the July 2010 print issue of the Journal of Leukocyte Biology, Japanese scientists use mice to show that bortezomib, currently used to treat cancers that affect white blood cells, induces cell death only in harmful (active and proliferating) T cells, leaving the rest unharmed.

1 Jul 2010

New chemical method for drug design, agrichemicals

University of Delaware scientist Donald Watson is part of a research team that has discovered an easier method for incorporating fluorine into organic molecules, giving chemists an important new tool in developing materials ranging from new medicines to agricultural chemicals.

30 Jun 2010

Biochemistry News and Research

KCI announces creation of Advanced Research and Technology center

Study identifies protein that turns non-malignant tumor into metastatic neuroendocrine tumor

British Mycological Society announces 'The Biology of Fungi' programme at IMC9

Researchers demonstrate that MSNs can effectively suppress tumors in mice

Research finding uncovers alternative treatments for people with hereditary colorectal cancer

IRIC scientists identify vitamin B3 as potential antifungal treatment

Japanese scientists identify long-elusive enzyme necessary for proper regulation of cilia

Article related to MN-166 mechanism of action included in PNAS USA

PolyMAC technique retrieves specific proteins needed to study formation of cancer cells

Silence strengthens RNAi IP portfolio with issuance of key patent in structural modification technology

Researchers develop computer program to accurately simulate protein folding

Patent issued for jellyfish protein for therapeutic application

Map of herpes virus "cell-entry machinery" provides new target for antiviral drugs

Study finds additional targets for new therapies to treat advanced prostate cancer patients

Antioxidant supplements increase artery elasticity in patients with multiple cardiovascular risk factors

Lensless cell phone microscope

FnBP is central to bacteria's ability to invade organs: Researchers

Studies link anti-cholesterol statin drugs to increased risk of anxiety and depression

Bortezomib may offer hope for treating inflammatory diseases: New research

New chemical method for drug design, agrichemicals

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