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B-cells have significant differences in women with postpartum depression, finds study

A study published in Molecular Psychiatry is the first to look at multiple levels of biology within women with postpartum depression (PPD) to see how women with the condition differ from those without it.

10 Apr 2022

Study shows benefits of Medicaid expansion for patients diagnosed with de novo stage 4 breast cancer

A new study led by Susan G. Komen® Scholars indicates that patients diagnosed with de novo stage 4 breast cancer – also called metastatic breast cancer– had improved survival rates and decreased mortality rates when those patients had access to care.

10 Apr 2022

Simple interventions reduced radiation exposure to the heart during lung cancer treatment

Radiation to the heart during treatment for locally advanced lung cancer is associated with an increased risk of major adverse cardiac events within the first two years following treatment. The higher the cardiac dose exposure, the higher the risk of a cardiac event.

8 Apr 2022

Researchers seek to understand how microbes in the GI tract help people resist pathogens

Published in Nature Communications, research from the University of Minnesota and Mayo Clinic sought to understand how microbial communities help people resist pathogens.

8 Apr 2022

Advanced microscopy reveals exciting insights into dynamic ultrastructure of the heart

What happens below the cellular level when the heart contracts and relaxes has long been unexplored. Thanks to new ultra-high-resolution electron microscopy techniques, scientists can now watch the heart beating – almost at a molecular level.

8 Apr 2022

Imbalances in the intestinal virome may promote inflammatory bowel disease, research shows

Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine?

8 Apr 2022

Study gains insight into the reasons behind low rate of birth registrations in Africa

In large parts of Africa, only half of all children are registered at birth. As a result, these unregistered children cannot, or only with difficultly, make claim to essential human rights later in life, be it healthcare, education or financial support.

8 Apr 2022

Study highlights factors that influence Alaskan brown bears' gut microbiome

A recent study of Alaskan brown bears (Ursus arctos) finds that there is significant variation in the gut microbiome of bear populations, depending on where the bears live.

8 Apr 2022

New delivery method enhances the "attack power" of CAR T cells against tumors

One cutting-edge cancer treatment exciting researchers today involves collecting and reprogramming a patient's T cells – a special set of immune cells – then putting them back into the body ready to detect and destroy cancerous cells.

8 Apr 2022

UNSW research improves fundamental understanding of the mechanism behind sickle cell disease

UNSW researchers have used CRISPR gene editing – a type of 'molecular scissors' – to understand how deletions in one area of the genome can affect the expression of nearby genes.

8 Apr 2022

Study reveals rapid increases in urban exposure to air pollutants hazardous to health

The international team of scientists aimed to address data gaps in air quality for 46* future megacities in Africa, Asia and the Middle East using space-based observations from instruments onboard NASA and European Space Agency (ESA) satellites for 2005 to 2018.

8 Apr 2022

Combination immunotherapy reverses resistance to PD-1 inhibitors in patients with advanced melanoma

Patients with advanced melanoma whose cancer does not respond to treatment with widely used immunotherapy drugs known as PD-1 inhibitors are often switched to treatment with a second type of immunotherapy drug – a CTLA-4 inhibitor such as the drug ipilimumab.

8 Apr 2022

Computational network science approach reveals new mechanisms for coronaviruses infections

A group of bat viruses related to SARS-CoV-2 can also infect human cells but uses a different and unknown entryway.

8 Apr 2022

City of Hope's late-breaking clinical trial data to be presented at AACR

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, will present late-breaking and clinical trial findings at this year's American Association for Cancer Research Annual Meeting, which begins today.

8 Apr 2022

Artificial intelligence model could predict side effects resulting from new combination therapies

Preliminary data from an artificial intelligence model could potentially predict side effects resulting from new combination therapies, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

8 Apr 2022

AI model uses electronic health records to identify people at high risk for pancreatic cancer

An artificial intelligence (AI) model trained using sequential health information derived from electronic health records identified a subset of individuals with a 25-fold risk of developing pancreatic cancer within three to 36 months, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

8 Apr 2022

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea.

8 Apr 2022

Many clinical trials fail to account for previous or ongoing studies, researchers show

Clinical trials are a pivotal tool for assessing the safety and efficacy of medical interventions, but sponsors often provide incomplete information for assessing their ethical justification.

8 Apr 2022

New Russian-language protocol for fMRI enables preoperative mapping of language areas

Neurolinguists from HSE University, in collaboration with radiologists from the Pirogov National Medical and Surgical Centre, developed a Russian-language protocol for functional magnetic resonance imaging (fMRI) that makes it possible to map individual language areas before neurosurgical operations.

8 Apr 2022

ADDF supports the need to gather more evidence about clinical effectiveness of anti-amyloid drug

On Thursday, April 7, the Centers for Medicare and Medicaid (CMS) formalized its plan to cover the anti-amyloid drug Aduhelm only for patients enrolled in clinical trials.

8 Apr 2022

Research News and Research

B-cells have significant differences in women with postpartum depression, finds study

Study shows benefits of Medicaid expansion for patients diagnosed with de novo stage 4 breast cancer

Simple interventions reduced radiation exposure to the heart during lung cancer treatment

Researchers seek to understand how microbes in the GI tract help people resist pathogens

Advanced microscopy reveals exciting insights into dynamic ultrastructure of the heart

Imbalances in the intestinal virome may promote inflammatory bowel disease, research shows

Study gains insight into the reasons behind low rate of birth registrations in Africa

Study highlights factors that influence Alaskan brown bears' gut microbiome

New delivery method enhances the "attack power" of CAR T cells against tumors

UNSW research improves fundamental understanding of the mechanism behind sickle cell disease

Study reveals rapid increases in urban exposure to air pollutants hazardous to health

Combination immunotherapy reverses resistance to PD-1 inhibitors in patients with advanced melanoma

Computational network science approach reveals new mechanisms for coronaviruses infections

City of Hope's late-breaking clinical trial data to be presented at AACR

Artificial intelligence model could predict side effects resulting from new combination therapies

AI model uses electronic health records to identify people at high risk for pancreatic cancer

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Many clinical trials fail to account for previous or ongoing studies, researchers show

New Russian-language protocol for fMRI enables preoperative mapping of language areas

ADDF supports the need to gather more evidence about clinical effectiveness of anti-amyloid drug

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