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Skin cell to liver cell shows promise for genetic liver disease

In a new scientific breakthrough, researchers have taken skin cells from a patient with liver disease and turned them into replacement liver cells. Although the procedure is years before it can be used in humans, but if approved, it could launch a new era of personalized therapies for serious genetic disorders.

13 Oct 2011

Affymetrix launches Axiom Pan-African Array

Affymetrix, Inc. today announced at the ICHG/ASHG annual conference in Montreal, the worldwide launch of the Axiom Genome-Wide Pan-African Array, the first commercial product to maximize genomic coverage of both common and rare alleles in populations of African ancestry, including West African, East African, and African American.

13 Oct 2011

Peanut allergy could be switched off

Now researchers may have discovered how to switch off food allergies. Researchers from Northwestern University found a way to tweak the immune system so that it doesn’t react when foods like peanuts and eggs are encountered – in mice.

12 Oct 2011

Intellikine commences INK1117 Phase I dose escalation study in cancer

Intellikine, Inc., a company focused on the discovery and development of innovative, small molecule drugs targeting the PI3K/mTOR pathway, announced today that the first patient has been treated in a Phase I dose escalation study of INK1117 in patients with advanced solid malignancies.

12 Oct 2011

German stem cell scientist wins annual Young Investigator Award in Serbia

A young scientist who led research into the use of stem cells from hair follicles to treat the ocular surface disease has been named the winner of the Young Investigator Award by the journal Stem Cells.

12 Oct 2011

British scientist wins NYSCF - Robertson Stem Cell Prize

The New York Stem Cell Foundation (NYSCF) announced today that a British stem cell scientist working to cure blindness will be the first recipient of The New York Stem Cell Foundation - Robertson Prize in Stem Cell Research, a $200,000 prize awarded annually for extraordinary achievement in translational stem cell research.

12 Oct 2011

Angle-resolved low coherence interferometry can diagnose pre-cancerous colon cells

After demonstrating that light accurately detected pre-cancerous cells in the lining of the esophagus, Duke University bioengineers turned their technology to the colon and have achieved similar results in a series of preliminary experiments.

12 Oct 2011

NCCN Oncology Research Program wins two GSK grants

The National Comprehensive Cancer Network Oncology Research Program (ORP) has been awarded $4 million in the form of two research grants from GlaxoSmithKline (GSK) to develop studies to scientifically evaluate and define GSK2118436, a BRAF inhibitor, and GSK1120212, a MEK1 and MEK2 inhibitor. Previous research has indicated that BRAF mutations are strong targets for therapies in the treatment of advanced melanoma.

12 Oct 2011

Idera announces new data on novel gene-silencing oligonucleotide technology

Idera Pharmaceuticals, Inc. today presented new data on its novel gene-silencing oligonucleotide (GSO) technology at the Cell Symposium on Regulatory RNAs in Chicago, IL.

12 Oct 2011

Vitamin D plays an essential role in the body's fight against TB

Not just important for building strong bones, an international team of scientists has found that vitamin D also plays an essential role in the body's fight against infections such as tuberculosis.

12 Oct 2011

Life Technologies launches Ion AmpliSeq Cancer Panel

Life Technologies Corporation today announced the launch of the Ion AmpliSeq Cancer Panel, enabling scientists to sequence dozens of genes in cancer research samples using a simple workflow.

12 Oct 2011

NIH, Genesis Biopharma enter Patent License Agreement for adoptive cell therapy

Genesis Biopharma, Inc., a biotechnology company developing targeted cancer immunotherapies, today announced it has entered into a Patent License Agreement with the National Institutes of Health, an agency of the United States Public Health Service within the Department of Health and Human Services

12 Oct 2011

UCLA's screening system can target stem cells responsible for glioblastoma

Researchers with UCLA's Jonsson Comprehensive Cancer Center have developed and used a high-throughput molecular screening approach that identifies and characterizes chemical compounds that can target the stem cells that are responsible for creating deadly brain tumors.

12 Oct 2011

Study: Emerging pharmaceutical platform may produce undesirable effects on eye function

According to new research by University of Kentucky investigators, an emerging pharmaceutical platform used in treating a variety of diseases may produce unintended and undesirable effects on eye function.

12 Oct 2011

Elsevier launches new browser for readers to explore protein interactions

Elsevier, a world-leading provider of scientific, medical and technical products and services, introduces the Protein Interaction Browser, a new application available on SciVerse ScienceDirect.

12 Oct 2011

Viewpoints: The value of testing for prostate cancer; rewards for transplant donors; Calif.'s medical marijuana problem

For men older than 50, a simple blood test to screen for prostate cancer is as much a part of annual physicals as weigh-ins and stethoscopes. The PSA test is painless, inexpensive and the only way to detect the disease -; the most common male cancer -; before symptoms turn up.

12 Oct 2011

New robust technique holds promise for identifying trace mutant DNA sequences

Molecular DNA testing methods offer clinicians powerful tools that serve to confirm or identify disease diagnoses. High sensitivity and high specificity, however, are frequently a challenge to achieve with these methods. In a study scheduled for publication in the November issue of The Journal of Molecular Diagnostics, researchers describe a new, robust technique that holds promise for identifying trace mutant DNA sequences in an overwhelming population of unmutated DNA.

12 Oct 2011

Progenra, Ono enter ubiquitin pathway research collaboration

Progenra, Inc. announced today that it has entered into a research collaboration with Ono Pharmaceutical Co., Ltd. Under the agreement, Progenra will collaborate with Ono to conduct assay development and high throughput screening by using Progenra's proprietary technology on multiple targets in the ubiquitin pathway.

11 Oct 2011

Antivirulence drugs may fight infection and suppress resistance

Antivirulence drugs disarm pathogens rather than kill them, and although they could be effective in theory, antivirulence drugs have never been tested in humans. A new study to be published in the online journal mBio- on Tuesday, October 18 reveals these drugs have the potential to fight infection while avoiding the pitfalls of drug resistance.

11 Oct 2011

Novel link between cell surface sugars, Darwinian sexual selection, and immune function

Researchers at the University of California, San Diego School of Medicine say that losing the ability to make a particular kind of sugar molecule boosted disease protection in early hominids, and may have directed the evolutionary emergence of our ancestors, the genus Homo.

11 Oct 2011