Anti Inflammatory News and Research

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Long-term use of NSAIDs cuts the risk for oral cancer in smokers by half but increases risk of cardiovascular problems

An analysis of 20 years of data on the health of over 900 adults has found that long-term use of traditional nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, cuts the risk for oral cancer in smokers by half.

9 Oct 2005

Large tumors that block the sinuses can be removed endoscopically through the nose

The endoscopic approach worked well not only to remove large inverted papillomas in 18 patients ages 36 to 74 but also to watch for regrowth of the tumors that have a high recurrence rate and a small chance of becoming cancer. Patients were treated as outpatients and 56 percent remained disease-free at 29 months.

5 Oct 2005

Study shows that high-fat diets correlate to a chronic inflammatory state in the liver,

Mice that were fed diets high in fat and sugar developed immune system abnormalities in their livers, including reduced numbers of natural killer T (NKT) cells. These diet-related changes may contribute to obesity-related liver disease, according to a new study.

3 Oct 2005

Substance found in cotton plant could help treat psoriasis

A substance found in the cotton plant could help treat the common skin disease psoriasis, according to new research from the Pharmacy School at Sunderland University launched at the British Pharmaceutical Conference in Manchester.

28 Sep 2005

The immune mechanisms of atherosclerosis

Scientists are depicting a novel scheme for atherosclerosis development, suggesting that this pathology might result from an imbalance between pro-inflammatory processes and calming ones.

28 Sep 2005

Fndings could lead to a treatment for idiopathic interstitial pneumonia

An incurable, deadly lung disorder, "idiopathic interstitial pneumonia" (IIP), whose causes were mysterious arises from a combination of a genetic predisposition and damage due to inhaled chemicals, notably from cigarette smoking, Duke University Medical Center researchers have found.

27 Sep 2005

Pomegranate juice shows major promise to combat prostate cancer

The juice of the pomegranate, say researchers at University of Wisconsin Medical School, shows major promise to combat prostate cancer - the most common invasive cancer and the second-leading cause of cancer death in American men.

27 Sep 2005

Potential oral drug for rheumatoid arthritis

A potential oral drug for rheumatoid arthritis (RA) may encourage women to treat their condition earlier rather than later because it is less arduous than currently available treatments. Early treatment is important because RA most often develops between the ages of 35 and 50 and is two- to three times more prevalent in women.

26 Sep 2005

Polymorphisms in a receptor called CD32 influence the response to antibody therapy in cancer

In a paper appearing online in advance of print publication of the October 1 issue of the Journal of Clinical Investigation, Adam Boruchov and colleagues from Memorial Sloan Kettering Cancer Center dissect the contributions of CD32 isoforms in human dendritic cell (DC) activation and function.

26 Sep 2005

Abatacept, marketed as Orencia appears to offer pain relief and increased mobility to rheumatoid arthritis patients

A new drug appears to offer pain relief and increased mobility to rheumatoid arthritis patients who have exhausted their other medical treatment options.

21 Sep 2005

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Their findings that a chemical imbalance might underlie such damage could also lead to the development of anti-inflammatory drugs without the adverse side effects, the researchers said.

20 Sep 2005

Salicylate an active metabolite of aspirin - weakens lipid membranes

It's well known that high doses of aspirin can cause ulcers and temporary deafness, but the biochemical mechanism responsible for these phenomena has never been deciphered.

19 Sep 2005

Nuclear receptor proteins could change anti-inflammatory treatments

Several nuclear receptor proteins appear to overlap in their ability to exert anti-inflammatory effects, according to new research by scientists at the University of California, San Diego (UCSD).

12 Sep 2005

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

Scientists from Stanford University say they have discovered that vitamin D, known as the "sunshine vitamin,"can limit the growth of prostate cancer cells when combined with non-steroidal anti-inflammatory drugs.

6 Sep 2005

IP 751 a marijuana-derived drug effectively suppresses pain and bladder overactivity in hypersensitive bladder disorders

IP 751, a potent synthetic analog of a metabolite of THC-the principal active ingredient of marijuana-effectively suppresses pain and bladder overactivity in hypersensitive bladder disorders such as interstitial cystitis (IC), according to animal model study results presented today at the annual meeting of the International Continence Society.

1 Sep 2005

Pomegranate fruit extracts can block enzymes that contribute to osteoarthritis

The study looked at the ability of an extract of pomegranate fruit against Interleukin-1b (IL-1b), a pro-inflammatory protein molecule that plays a key role in cartilage degradation in osteoarthritis.

1 Sep 2005

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs, taken in combination, have been shown to act as a powerful one-two punch that knocks down the growth of prostate cancer cells.

1 Sep 2005

Extra-virgin olive oil tastes good and is also an anti-inflammatory

After a tasting experience at a molecular gastronomy meeting in Sicily, biologist Gary Beauchamp of Pennsylvania University decided to analyse freshly pressed extra-virgin olive oil and found a chemical that acted like ibuprofen in the oil.

31 Aug 2005

Relative of the celebrated COX-2 inhibitor celecoxib is tough tumor fighter

A close structural relative of the celebrated COX-2 inhibitor celecoxib (brand name: Celebrex) is a potent tumor fighter, able to wipe out tumor cells that are resistant to conventional chemotherapies, according to an interdisciplinary team of researchers from the University of Southern California.

29 Aug 2005

Taking aspirin longterm could reduce colorectal cancer risk

According to new report from the Nurses' Health Study (NHS), regular, long-term aspirin use can significantly reduce the risk of colorectal cancer.

24 Aug 2005

Anti Inflammatory News and Research

Long-term use of NSAIDs cuts the risk for oral cancer in smokers by half but increases risk of cardiovascular problems

Large tumors that block the sinuses can be removed endoscopically through the nose

Study shows that high-fat diets correlate to a chronic inflammatory state in the liver,

Substance found in cotton plant could help treat psoriasis

The immune mechanisms of atherosclerosis

Fndings could lead to a treatment for idiopathic interstitial pneumonia

Pomegranate juice shows major promise to combat prostate cancer

Potential oral drug for rheumatoid arthritis

Polymorphisms in a receptor called CD32 influence the response to antibody therapy in cancer

Abatacept, marketed as Orencia appears to offer pain relief and increased mobility to rheumatoid arthritis patients

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Salicylate an active metabolite of aspirin - weakens lipid membranes

Nuclear receptor proteins could change anti-inflammatory treatments

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

IP 751 a marijuana-derived drug effectively suppresses pain and bladder overactivity in hypersensitive bladder disorders

Pomegranate fruit extracts can block enzymes that contribute to osteoarthritis

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Extra-virgin olive oil tastes good and is also an anti-inflammatory

Relative of the celebrated COX-2 inhibitor celecoxib is tough tumor fighter

Taking aspirin longterm could reduce colorectal cancer risk

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