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TSRI scientists uncover regulatory machinery underlying the function of cancer protein

Despite intense research, there's been much confusion regarding the exact role of a protein in a critical cancer-linked pathway. On one hand, the protein is described as a cell proliferation inhibitor, on the other, a cell proliferation activator, a duality that has caused a great deal of scientific head scratching.

5 May 2017

Advancing safety in healthcare products

True benefit from healthcare products requires an unrelenting focus on patient- and consumer-centered safety, a principle that is at the heart of J&J’s Credo and is embodied in the mission of the Office of the Chief Medical Officer (OCMO).

From Johnson & Johnson 5 May 2017

Easing cellular traffic jams in Huntington’s disease may save brain cells

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center - the nucleus- appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

5 May 2017

UAB spinoff develops drug-resistant immunotherapy to combat solid tumors

The University of Alabama at Birmingham and two partner institutions have received a European patent for their novel approach to fighting cancer, an approach that is led by the UAB spinoff biopharmaceutical company Incysus Ltd.

5 May 2017

Pediatric cardiology expert advises pregnant women to ask three questions about fetal ultrasounds

For pregnant women, it is standard practice to get a general fetal ultrasound between 18 to 22 weeks of pregnancy. Ultrasound scans, which use high-frequency sound waves to show images of the fetus, placenta and amniotic fluid, help the doctor see how the baby is developing and detect possible birth defects.

5 May 2017

New research identifies immunotherapy targets to offer hope for early-stage lung cancer patients

Immunotherapy, which has achieved remarkable results in late-stage lung cancer patients, can also hold great hope for newly diagnosed patients, cutting the deadly disease off before it has the chance to take hold and offering a potential cure, according to a new Mount Sinai study published today in Cell.

4 May 2017

Discovery of signaling pathway offers new functional framework for treating schizophrenia

Neuroscientists at Tufts University School of Medicine have discovered a new signaling pathway that directly connects two major receptors in the brain associated with learning and memory – the N-methyl-D-aspartate receptor (NMDAR) and the alpha 7 nicotinic acetylcholine receptor (a7nAChR) – which has significance for current efforts to develop drugs to treat schizophrenia.

4 May 2017

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Although the odds of developing breast cancer are nearly identical for black and white women, black women are 42 percent more likely to die from the disease. This mortality gap – driven by social and environmental, as well as biological factors – continues to persist.

4 May 2017

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

Columbia University Medical Center researchers have discovered a molecular mechanism that reprograms tumor cells in patients with advanced prostate cancer, reducing their response to anti-androgen therapy.

4 May 2017

GW scientist awarded $1.7 million grant to understand mechanisms behind Hedgehog receptor

Among scientists specializing in the area, the mechanisms behind the signaling function of the Hedgehog (Hh) receptor pathway remain a mystery. Xiaoyen Zheng, Ph.D., assistant professor of anatomy and regenerative biology at the George Washington University School of Medicine and Health Sciences, who recently received a $1.7 million grant from the National Institutes of Health and National Institute of General Medical Sciences, is determined to learn more about the Hh pathway.

4 May 2017

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

Researchers investigating a form of adult-onset diabetes that shares features with the two better-known types of diabetes have discovered genetic influences that may offer clues to more accurate diagnosis and treatment.

4 May 2017

Permanent funding solution essential to ensure future of unique primary care residency program

It's too soon for Shayla Durfey to know whether she'll apply for a Teaching Health Centers residency when she graduates from the Warren Alpert Medical School of Brown University in a few years -- but as she and two professors write online in JAMA, the unique opportunity won't still exist for her or other medical students without action from Congress.

4 May 2017

Study finds higher rates of suicidal thoughts and attempts among transgender adults

Suicidal thoughts and attempts by adult transgender individuals were 14 and 22 times higher, respectively, than rates for the general public, according to a new study published in Transgender Health, a peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers. The article is available open access on the Transgender Health website.

4 May 2017

American Cancer Society awards new $792,000 grant to Yale researcher

The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding of a new research grant totaling $792,000 to a researcher at Yale University.

4 May 2017

Scientists identify differences in outcomes for women and men with AFF in emergency departments

Atrial fibrillation and flutter (also known as AFF) is associated with serious health problems and is a significant contributor to death rates.

4 May 2017

Disrupting the circadian clock can alter gut microbiome and the body's response to diet

Researchers at Baylor College of Medicine have discovered that changing the circadian clock in mouse liver can alter how the body responds to diet and also change the microbes living in the digestive track.

4 May 2017

Newly-developed smart contact lens sensor may help diagnose diabetes and glaucoma

A recent study, affiliated with UNIST has proposed the possibility of in situ human health monitoring simply by wearing a contact lens with built-in wireless smart sensors.

4 May 2017

Researchers identify biomarker that could predict disease severity in glaucoma patients

Glaucoma, a leading cause of blindness worldwide, most often is diagnosed during a routine eye exam. Over time, elevated pressure inside the eye damages the optic nerve, leading to vision loss. Unfortunately, there's no way to accurately predict which patients might lose vision most rapidly.

4 May 2017

$New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds$

New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds

A team of researchers of the University of Barcelona and the Hospital del Mar Medical Research Institute have discovered a new mutation that has an impact on the bone so that it is vulnerable to the bisphosphonate, a drug used to treat osteoporosis.

4 May 2017

Study shows first removal of HIV-1 replication using CRISPR/Cas9, gene editing technology

A new study published in the journal Molecular Therapy reveals that HIV DNA in the genome of living animals can be removed to eliminate further infection. While a permanent cure for infection caused by HIV remains a challenge due to the ability of the virus to hide away in latent reservoirs. The study team comprising Wenhui Hu, Kamel Khalili, Laura H. Carnell, and Won-Bin Young carried out an experiment on three different animal models.

4 May 2017

Medicine News and Research

TSRI scientists uncover regulatory machinery underlying the function of cancer protein

Advancing safety in healthcare products

Easing cellular traffic jams in Huntington’s disease may save brain cells

UAB spinoff develops drug-resistant immunotherapy to combat solid tumors

Pediatric cardiology expert advises pregnant women to ask three questions about fetal ultrasounds

New research identifies immunotherapy targets to offer hope for early-stage lung cancer patients

Discovery of signaling pathway offers new functional framework for treating schizophrenia

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

GW scientist awarded $1.7 million grant to understand mechanisms behind Hedgehog receptor

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

Permanent funding solution essential to ensure future of unique primary care residency program

Study finds higher rates of suicidal thoughts and attempts among transgender adults

American Cancer Society awards new $792,000 grant to Yale researcher

Scientists identify differences in outcomes for women and men with AFF in emergency departments

Disrupting the circadian clock can alter gut microbiome and the body's response to diet

Newly-developed smart contact lens sensor may help diagnose diabetes and glaucoma

Researchers identify biomarker that could predict disease severity in glaucoma patients

New mutation predisposes patients under osteoporosis treatment to atypical femur fractures, study finds

Study shows first removal of HIV-1 replication using CRISPR/Cas9, gene editing technology

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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