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New UCSB technology can identify cancerous prostate cells

A team of researchers at UC Santa Barbara has developed a breakthrough technology that can be used to discriminate cancerous prostate cells in bodily fluids from those that are healthy.

20 Sep 2011

UNC researchers develop technique that can observe cellular intricacies of CF

When researchers discovered the primary genetic defect that causes cystic fibrosis (CF) back in 1989, they opened up a new realm of research into treatment and a cure for the disease. Since then, scientists have been able to clone the defective gene and study its effects in animals. Now researchers at the University of North Carolina at Chapel Hill have developed a technique for observing the defects at work in human tissue donated by patients with CF.

20 Sep 2011

Keryx completes enrollment in Zerenex Phase 3 long-term study for hyperphosphatemia

Keryx Biopharmaceuticals today announced completion of patient enrollment in the long-term study component of its Phase 3 registration program of Zerenex, the Company's ferric iron-based phosphate binder for the treatment of elevated serum phosphorus levels, or hyperphosphatemia, in patients with end-stage renal disease (ESRD) on dialysis.

20 Sep 2011

Multispectral fluorescence imaging system can localize cancer cells during surgery

Ovarian cancer is one of the most frequent forms of cancer that affect women. As tumors can initially grow unchecked in the abdomen without causing any major symptoms, patients are usually diagnosed at an advanced stage and have to undergo surgery plus chemotherapy. During the operation, surgeons attempt to remove all tumor deposits as this leads to improved patient prognosis. To do this, however, they primarily have to rely on visual inspection and palpation - an enormous challenge especially in the case of small tumor nests or remaining tumor borders after the primary tumor excision.

20 Sep 2011

Scientists pioneer new combination treatment for prostate cancer

Scientists at Queen's University have pioneered a new combination treatment for prostate cancer. The treatment, which has been successful in phase one of trials, will now be tested for efficacy in a second phase.

20 Sep 2011

Positive data from NovaDigm's NDV-3 vaccine preclinical study on VVC

NovaDigm Therapeutics, a company developing innovative vaccines for fungal and bacterial infections, today announced the presentation of positive data from a preclinical study evaluating the efficacy its NDV-3 vaccine in a model of vulvovaginal candidiasis (VVC), which is primarily caused by Candida albicans.

20 Sep 2011

Preclinical studies shows EmPAC more effective than Taxol

Cornerstone Pharmaceuticals, Inc. has announced the publication of data from preclinical studies on EmPAC™, its nanoparticle reformulation of paclitaxel, in the August issue of the Journal of Nanoscience and Nanotechnology. The publication highlights data demonstrating improved safety and efficacy of EmPAC™ versus Taxol®, the generic formulation of paclitaxel and one of the most widely prescribed chemotherapies. EmPAC™ is a nanoemulsion formulation of Paclitaxel and is the lead product candidate of Cornerstone’s proprietary Emulsiphan™ cancer selective delivery nanotechnology platform. Taxol®, an injectable formulation of Paclitaxel, is currently used to treat a variety of cancers, including ovarian carcinomas, breast cancer, non-small cell lung cancer, and AIDS-related Kaposi’s sarcoma.

19 Sep 2011

High dietary salt intake and obesity together trigger abnormal activation of cellular protein

Dietary salt intake and obesity are two important risk factors in the development of high blood pressure. Each packs its own punch, but when combined, they deliver more damage to the heart and kidneys than the sum of their individual contributions.

19 Sep 2011

Amgen's Prolia receives FDA approval for new indications to treat cancer patients

Amgen today announced that the U.S. Food and Drug Administration (FDA) approved two new indications for Prolia® (denosumab) as a treatment to increase bone mass in women at high risk for fracture receiving adjuvant aromatase inhibitor therapy for breast cancer and as a treatment to increase bone mass in men at high risk for fracture receiving androgen deprivation therapy for non-metastatic prostate cancer.

19 Sep 2011

Positive Phase 1 data for NovaDigm NDV-3 vaccine presented at 51st ICAAC

NovaDigm Therapeutics, a company developing innovative vaccines for fungal and bacterial infections, today announced the presentation of positive Phase 1 data for its NDV-3 vaccine program at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

19 Sep 2011

Top-line data from Spectrum's SPI-1620 Phase 1 combination study on carcinoma

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in hematology and oncology, today announced that top-line data from part one of a two-part Phase 1 study of SPI-1620 in combination with docetaxel was presented in an oral presentation at the 12th International Conference on Endothelin, held in Cambridge, United Kingdom, from September 11-14, 2011. Part one of the study has been completed, while part two is ongoing.

19 Sep 2011

Techulon signs distribution agreement with BioConcept for Glycofect

Techulon Inc., the leader in low-toxicity gene delivery has signed a distribution agreement with BioConcept of Allschwil, Switzerland.

19 Sep 2011

NeuroVive, Selcia sign research collaboration agreement to develop new mitochondrial drugs

UK-based contract research organisation Selcia Limited and Swedish drug development company NeuroVive Pharmaceutical AB have signed a significant research collaboration agreement to develop new medicines and drug compounds targeting mitochondrial physiology and pathophysiology.

19 Sep 2011

NTNU genetic research shows best recipe to limit risk of lifestyle-related diseases

What should we eat? Answers abound in the international media, all of which rely on their interpretation of recent medical literature to come up with recommendations for the healthiest diet. But what if you could answer this question at a molecular level - what if you could find out how our genes respond to the foods we eat, and what this does to the cellular processes that make us healthy - or not? That's precisely what biologists at the Norwegian University of Science and Technology have done.

19 Sep 2011

University of Groningen surgeons perform first fluorescence-guided ovarian cancer surgery

The first fluorescence-guided surgery on an ovarian cancer patient was performed using a cancer cell "homing device" and imaging agent created by a Purdue University researcher.

19 Sep 2011

Two newer Type 2 diabetes drugs could be linked to increased risk of pancreatic cancer

Two newer drugs used to treat Type 2 diabetes could be linked to a significantly increased risk of developing pancreatitis and pancreatic cancer, and one could also be linked to an increased risk of thyroid cancer, according to a new UCLA study.

19 Sep 2011

Nanoparticles have a detrimental effect on the fish brain

Scientists at the University of Plymouth have shown, for the first time in an animal, that nanoparticles have a detrimental effect on the brain and other parts of the central nervous system.

19 Sep 2011

Researchers reveal crystal structure of dynamin protein

The crystal structure of the dynamin protein - one of the molecular machines that makes cells work - has been revealed, bringing insights into a class of molecules with a wide influence on health and disease.

19 Sep 2011

Landmark international study confirms common genetic contribution to mental illness

An international research consortium has confirmed that common genetic variants contribute to a person’s risk of schizophrenia and bipolar disorder. The largest study of its kind provides new molecular evidence that 11 regions have strong association with these diseases, including six regions not previously observed. The researchers also found that many of these DNA variations contribute to both diseases. The findings, reported by the Psychiatric Genome-Wide Association Study Consortium (PGC) and published online in two papers in the journal Nature Genetics, represent significant advances in the understanding the causes of these severe and often debilitating disorders.

18 Sep 2011

An evening of grace and glamour to benefit people living with HIV/AIDS in Orange County

AIDS Services Foundation Orange County (ASF) will literally roll out the red carpet for its signature fund raising event – Red Ball II on Saturday, September 24 at the Festival of Arts in Laguna Beach at 6 p.m.

17 Sep 2011

Cell News and Research

New UCSB technology can identify cancerous prostate cells

UNC researchers develop technique that can observe cellular intricacies of CF

Keryx completes enrollment in Zerenex Phase 3 long-term study for hyperphosphatemia

Multispectral fluorescence imaging system can localize cancer cells during surgery

Scientists pioneer new combination treatment for prostate cancer

Positive data from NovaDigm's NDV-3 vaccine preclinical study on VVC

Preclinical studies shows EmPAC more effective than Taxol

High dietary salt intake and obesity together trigger abnormal activation of cellular protein

Amgen's Prolia receives FDA approval for new indications to treat cancer patients

Positive Phase 1 data for NovaDigm NDV-3 vaccine presented at 51st ICAAC

Top-line data from Spectrum's SPI-1620 Phase 1 combination study on carcinoma

Techulon signs distribution agreement with BioConcept for Glycofect

NeuroVive, Selcia sign research collaboration agreement to develop new mitochondrial drugs

NTNU genetic research shows best recipe to limit risk of lifestyle-related diseases

University of Groningen surgeons perform first fluorescence-guided ovarian cancer surgery

Two newer Type 2 diabetes drugs could be linked to increased risk of pancreatic cancer

Nanoparticles have a detrimental effect on the fish brain

Researchers reveal crystal structure of dynamin protein

Landmark international study confirms common genetic contribution to mental illness

An evening of grace and glamour to benefit people living with HIV/AIDS in Orange County

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