Vascular News and Research

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Arterial imaging with 3-D MRI could help to determine stroke risk among diabetics

People with diabetes may be harboring advanced vascular disease that could increase their risk of stroke, according to new research being presented next week at the annual meeting of the Radiological Society of North America.

24 Nov 2015

Vibration-based technology reduces apneic events, improves critical clinical parameters in premature infants

Scientists and clinicians at the University of Massachusetts Medical School, Wyss Institute for Biologically Inspired Engineering, and the Beth Israel Deaconess Medical Center have shown in a clinical trial that a new, vibration-based prevention technology tested in a neonatal intensive care unit (NICU) reduces apneic events and improves critical clinical parameters in prematurely born infants.

24 Nov 2015

Study finds significant reduction in diabetes-related amputation rates since the mid-1990s

A major new study has found a significant reduction in diabetes-related amputations since the mid-1990s, credited to improvements in diabetes care over this period. The research is published in Diabetologia (the journal of the European Association for the Study of Diabetes) and is by Dr Benjamin Rasmussen and Professor Henning Beck-Nielsen, Odense University Hospital Denmark, and colleagues.

23 Nov 2015

TVA Medical announces results from multicenter clinical study of everlinQ endoAVF System

TVA Medical, Inc., announced clinical trial results from a prospective, multicenter clinical study evaluating the everlinQ endoAVF System. This innovative medical technology creates hemodialysis access using vascular sites not traditionally used by surgeons for people with end-stage kidney disease (ESKD).

21 Nov 2015

Mount Sinai Roosevelt to be renamed as Mount Sinai West

The Mount Sinai Health System today announced that Mount Sinai Roosevelt will be renamed as Mount Sinai West. The hospital will continue to be the premier health care provider on the West Side of Manhattan, with all services continuing, the same insurances accepted and the same number of people employed.

18 Nov 2015

Researchers find ranibizumab drug as effective alternative to laser therapy for treating diabetic retinopathy

In a randomized clinical trial of more than 300 participants, researchers from Johns Hopkins and elsewhere have found that ranibizumab — a drug most commonly used to treat retinal swelling in people with diabetes — is an effective alternative to laser therapy for treating the most severe, potentially blinding form of diabetic retinal disease. Results of the government-sponsored study also show that the drug therapy carries fewer side effects than the currently used laser treatment.

17 Nov 2015

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

University of Cincinnati researchers have discovered the negative impact a high fat diet has on red blood cells and how these cells, in turn, promote the development of cardiovascular disease.

17 Nov 2015

Haemodynamic variables may distinguish pre- from post-capillary PH

Researchers have identified the haemodynamic variables that best distinguish between patients with idiopathic pulmonary arterial hypertension and isolated post-capillary pulmonary hypertension.

16 Nov 2015

Research collaboration aims to develop new drug for slow-healing chronic wounds

The biotech company Omnio based in Swedish Umeå, and led by researcher Tor Ny at Umeå University, launches a research collaboration with the Canadian pharmaceutical company ProMetic to develop a new drug for slow-healing chronic wounds. The collaboration includes funding for clinical studies of a drug based on the blood plasma protein plasminogen.

15 Nov 2015

Tyrogenex announces results from phase 1 study of orally-administered X-82 in patients with AMD

Tyrogenex, a privately held company focused on the development of targeted therapeutics for cancer and ophthalmology, today announced data from its phase 1 open-label study of orally-administered X-82 in patients for wet age-related macular degeneration (AMD).

15 Nov 2015

Ranibizumab may become reasonable treatment alternative for patients with proliferative diabetic retinopathy

Among patients with proliferative diabetic retinopathy, treatment with an injection in the eye of the drug ranibizumab resulted in visual acuity that was not worse than panretinal photocoagulation at 2 years, according to a study appearing in JAMA.

15 Nov 2015

Vanderbilt study could lead to development of new drugs that relieve pain without causing vascular effects

It's been about a decade since the promise of COX-2 inhibitors -- drugs that relieve arthritis pain and inflammation without the gastrointestinal side effects of other painkillers -- was tempered by the realization that they could cause heart problems in some patients.

13 Nov 2015

Johns Hopkins researchers present new healthcare tips from American Heart Association Meeting

Linking digital activity trackers to smartphones and periodically pinging users with personalized texts that urge them to walk more can significantly increase physical activity levels and spark healthy behavior changes, according to findings of a pilot study conducted at Johns Hopkins.

13 Nov 2015

Mayo Clinic's Florida campus awarded NIH grant to identify vascular risk factors in aging and dementia

Mayo Clinic's Florida campus was awarded a $5.3 million grant from the National Institutes of Health to identify vascular risk factors in aging and dementia, and translate that knowledge into studying potential targets for treatment.

12 Nov 2015

Lowering blood pressure below currently recommended targets reduces risk of stroke, heart attack

Using intensive treatment to lower blood pressure below currently recommended targets significantly reduces rates of major cardiovascular events like stroke and heart attack among a wide range of high-risk patients, according to a large meta-analysis involving almost 45000 individuals, published in The Lancet.

11 Nov 2015

White coat hypertension, masked hypertension increase cardiovascular events over the years

Patients whose blood pressures spikes in the doctor's office but not at home, and patients whose blood pressure spikes at home but not in the doctor's office, suffer more heart attacks, heart failure, and strokes than patients with normal blood pressures in both settings, UT Southwestern Medical Center researchers have found.

10 Nov 2015

New Haven Pharmaceuticals' DURLAZA drug delivers sustained antiplatelet control for full 24 hours

New Haven Pharmaceuticals, Inc. today announced new study data that shows the company's FDA-approved drug DURLAZA delivers sustained antiplatelet control for a full 24-hour period in high-risk patients.

10 Nov 2015

Sorafenib increases progression-free survival and disease control rate in NSCLC patients

Sorafenib, a tyrosine kinase inhibitor (TKI) targeting the receptors for vascular endothelial growth factor, platelet derived growth factor, and mast/stem cell growth factor, modestly increases progression-free survival (PFS), time to progression, and disease control rate in non-small cell lung cancer (NSCLC) patients who have relapsed or failed two or three previous treatment regimens.

10 Nov 2015

Disclosing genetic risk for CHD results in lower low-density lipoprotein cholesterol

A group of researchers led by Mayo Clinic has discovered that disclosing genetic risk for coronary heart disease (CHD) results in lower low-density lipoprotein cholesterol (LDL), also known as bad cholesterol. The findings of the Myocardial Infarction Genes (MI-GENES) Study were presented today at the annual American Heart Association Scientific Sessions 2015 as a late-breaking clinical trial.

10 Nov 2015

New treatment may help patients with chronic renovascular disease

A new treatment may help patients with a chronic kidney condition that can also lead to heart problems and premature death, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

6 Nov 2015

Vascular News and Research

Arterial imaging with 3-D MRI could help to determine stroke risk among diabetics

Vibration-based technology reduces apneic events, improves critical clinical parameters in premature infants

Study finds significant reduction in diabetes-related amputation rates since the mid-1990s

TVA Medical announces results from multicenter clinical study of everlinQ endoAVF System

Mount Sinai Roosevelt to be renamed as Mount Sinai West

Researchers find ranibizumab drug as effective alternative to laser therapy for treating diabetic retinopathy

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

Haemodynamic variables may distinguish pre- from post-capillary PH

Research collaboration aims to develop new drug for slow-healing chronic wounds

Tyrogenex announces results from phase 1 study of orally-administered X-82 in patients with AMD

Ranibizumab may become reasonable treatment alternative for patients with proliferative diabetic retinopathy

Vanderbilt study could lead to development of new drugs that relieve pain without causing vascular effects

Johns Hopkins researchers present new healthcare tips from American Heart Association Meeting

Mayo Clinic's Florida campus awarded NIH grant to identify vascular risk factors in aging and dementia

Lowering blood pressure below currently recommended targets reduces risk of stroke, heart attack

White coat hypertension, masked hypertension increase cardiovascular events over the years

New Haven Pharmaceuticals' DURLAZA drug delivers sustained antiplatelet control for full 24 hours

Sorafenib increases progression-free survival and disease control rate in NSCLC patients

Disclosing genetic risk for CHD results in lower low-density lipoprotein cholesterol

New treatment may help patients with chronic renovascular disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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