Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

People with prehypertension have higher risk of experiencing future stroke

People with prehypertension have a 55 percent higher risk of experiencing a future stroke than people without prehypertension, report researchers at the University of California, San Diego School of Medicine in a new meta-analysis of scientific literature published in the September 28 online issue of the journal Neurology.

29 Sep 2011

Engager Transcatheter Aortic Valve Implantation System pivotal trial to be conducted at 11 European centers

Medtronic, Inc. today announced the start of the Engager European Pivotal Trial to pursue CE Mark for the Engager Transcatheter Aortic Valve Implantation System in patients suffering from severe aortic stenosis.

From Medtronic 28 Sep 2011

Patients with chronic conditions likely to change their preferences for CPR

Patients with chronic conditions are likely to change their preferences for receiving emergency procedures in the event of cardiac arrest, according to new findings.

27 Sep 2011

Research roundup: Widows and medical spending; disparities in heart care, hospital deaths

The authors write: "We find that out-of-pocket medical spending is approximately 29 percent higher when an individual becomes widowed, a large portion of which is spending on nursing homes. Our results suggest a substantial role of living arrangements in out-of-pocket medical spending; however, our estimates combined with differences in rates of widowhood across gender suggest that marital status can explain only one third of the gender difference in total out-of-pocket medical spending, leaving a large portion unexplained.

27 Sep 2011

Men over 75 with prostate cancer are being undertreated: Study

It's an ongoing debate: Should men over a certain age be treated for prostate cancer? Should these patients be submitted to treatments that may result in significant side effects if they may not live very much longer?

27 Sep 2011

Genentech announces results of trastuzumab emtansine Phase II study on HER2-positive mBC

Genentech, a member of the Roche Group, today announced the results of the Phase II study TDM4450g in people with previously untreated HER2-positive metastatic breast cancer.

26 Sep 2011

'Time matters' in the fight against pulmonary hypertension

The Pulmonary Hypertension Association Europe (PHA EU) has launched ‘Time Matters’ a new campaign which encourages people with Pulmonary Hypertension (PH) and their friends and family to share hopes and dreams for the future in order to raise awareness of this deadly and rapidly progressive condition. By logging on to the website http://phtimematters.org and posting an entry, everybody can help the patient association take a step towards increased awareness and understanding of this devastating condition.

26 Sep 2011

Complications requiring hospitalization after prostate biopsy rise: Study

In a study of complication rates following prostate biopsy among Medicare beneficiaries, Johns Hopkins researchers have found a significant rise in serious complications requiring hospitalization.

23 Sep 2011

Ambrx, Bristol-Myers Squibb collaborate for novel biologics to treat heart failure and diabetes

Bristol-Myers Squibb Company and Ambrx, Inc. today announced a collaboration under which Bristol-Myers Squibb will receive exclusive worldwide rights to research, develop and commercialize biologics based on Ambrx's research surrounding the Fibroblast Growth Factor 21 protein, for potential use in treating type 2 diabetes, and the Relaxin hormone, for potential use in treating heart failure.

23 Sep 2011

Levosimendan may effectively improve muscle function in patients with respiratory failure

Treatment with the calcium-sensitizing drug levosimendan may be effective in improving muscle function in patients with respiratory muscle weakness, which often accompanies chronic diseases such as chronic obstructive pulmonary disease (COPD) and congestive heart failure, according to researchers in the Netherlands, who studied the effects of the drug on healthy volunteers.

23 Sep 2011

Cambridge Heart enters agreement with EO Medical for MTWA technology

Cambridge Heart, Inc., a developer of non-invasive diagnostic tests for cardiac disease, today announced that it has executed an exclusive agreement with EO Medical Pte Ltd to distribute its HearTwave II System and proprietary Microvolt T-Wave Alternans (MTWA) software and Micro-V Alternans Sensors in Singapore upon regulatory approval.

22 Sep 2011

Poor neighborhoods linked to higher risk of out-of-hospital cardiac deaths

People living in poor neighborhoods are at higher risk of dying of heart disease outside a hospital than are people who live in wealthier neighborhoods, research suggests.

21 Sep 2011

Risk factors for variety of complications following spine surgery

In the last 20 years, due to diagnostic and surgical advances, more and more patients have become appropriate candidates for spine surgery, and the number of these procedures performed has risen significantly. While medical experts acknowledge the potential benefits of spine surgery, they also understand that complications can reduce the success in the short and long term.

21 Sep 2011

U-M Professor to review data from three prominent studies on heart failure

Roughly 5 million people in the United States live with heart failure, a condition in which the heart is unable to pump blood around the body effectively. The causes and types of heart failure vary greatly, and treatment must be tailored to each patient. In some cases, doctors will prescribe a class of diuretic drugs called aldosterone antagonists.

20 Sep 2011

Enrollment commences in MINI-AMI study of Impella in STEMI patients

Abiomed, Inc., a leading provider of breakthrough heart support technologies, today announced the first patient enrolled in MINI-AMI, an FDA prospective, randomized, controlled multi-center study to assess the role of 24-hours of direct unloading of the left ventricle with Impella 2.5 support to reduce infarct size in patients with ST-elevation myocardial infarction (STEMI) without cardiogenic shock.

19 Sep 2011

NeuroVive, Selcia sign research collaboration agreement to develop new mitochondrial drugs

UK-based contract research organisation Selcia Limited and Swedish drug development company NeuroVive Pharmaceutical AB have signed a significant research collaboration agreement to develop new medicines and drug compounds targeting mitochondrial physiology and pathophysiology.

19 Sep 2011

HFSA scientific meeting to discuss long-term management care for LVAD patients

The 15th Annual Scientific Meeting of the Heart Failure Society of America (HFSA) will feature a discussion by Laura Coyle, ACNP, on strategies for caring for LVAD patients in an outpatient setting entitled "Long-Term Management: Caring for Patients to Keep Them at Home."

19 Sep 2011

Research roundup: Personalized info helps consumer decision-making; Racial disparities in knee replacement

Comparison Friction: Experimental Evidence From Medicare Drug Plans – Defining comparison friction as "the wedge between the availability of comparative information and consumers' use of it," the authors determined that providing prescription drug pricing information, even though it was free and accessible in other ways, increased the amount of "plan-switching" in the group to 28 percent compared to 17 percent in another that did not get the individual information.

17 Sep 2011

Estrogen therapy can reverse progression of pulmonary hypertension

UCLA researchers have found that the hormone estrogen may help reverse advanced pulmonary hypertension, a rare and serious condition that affects 2 to 3 million individuals in the U.S., mostly women, and can lead to heart failure.

16 Sep 2011

St. Jude Medical to again participate in Asia-Pacific Heart Rhythm Society Scientific Session

St. Jude Medical, Inc., a global medical device company, is pleased to again participate in the Asia-Pacific Heart Rhythm Society Scientific Session (APHRS), which is being held this year in conjunction with the Japanese Heart Rhythm Society (JHRS) and the Japanese Society of Electrocardiology (JSE) in Fukuoka, Japan.

16 Sep 2011

Heart Failure News and Research

Further Reading

People with prehypertension have higher risk of experiencing future stroke

Engager Transcatheter Aortic Valve Implantation System pivotal trial to be conducted at 11 European centers

Patients with chronic conditions likely to change their preferences for CPR

Research roundup: Widows and medical spending; disparities in heart care, hospital deaths

Men over 75 with prostate cancer are being undertreated: Study

Genentech announces results of trastuzumab emtansine Phase II study on HER2-positive mBC

'Time matters' in the fight against pulmonary hypertension

Complications requiring hospitalization after prostate biopsy rise: Study

Ambrx, Bristol-Myers Squibb collaborate for novel biologics to treat heart failure and diabetes

Levosimendan may effectively improve muscle function in patients with respiratory failure

Cambridge Heart enters agreement with EO Medical for MTWA technology

Poor neighborhoods linked to higher risk of out-of-hospital cardiac deaths

Risk factors for variety of complications following spine surgery

U-M Professor to review data from three prominent studies on heart failure

Enrollment commences in MINI-AMI study of Impella in STEMI patients

NeuroVive, Selcia sign research collaboration agreement to develop new mitochondrial drugs

HFSA scientific meeting to discuss long-term management care for LVAD patients

Research roundup: Personalized info helps consumer decision-making; Racial disparities in knee replacement

Estrogen therapy can reverse progression of pulmonary hypertension

St. Jude Medical to again participate in Asia-Pacific Heart Rhythm Society Scientific Session

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