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Growing up with siblings may provide some protection against divorce as adult

Growing up with siblings may provide some protection against divorce as an adult, a new nationwide study reveals. And the more siblings, the better: Each additional sibling a person has (up to about seven) reduces the likelihood of divorce by 2 percent.

13 Aug 2013

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Loss of a gene required for stem cells in the brain to turn into neurons may underlie the most severe forms of neuroblastoma, a deadly childhood cancer of the nervous system, according to a Ludwig Cancer Research study.

13 Aug 2013

Researchers explore potential of neural stem cells to repair brain damage

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body’s source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Researchers create an efficient technique to target and repair defective genes

Using human pluripotent stem cells and DNA-cutting protein from meningitis bacteria, researchers from the Morgridge Institute for Research and Northwestern University have created an efficient way to target and repair defective genes.

13 Aug 2013

Learning "grammar" helps determine whether gene gets switched on or not

Researchers have probed deep into the cell's genome, beyond the basic genetic code, to begin learning the "grammar" that helps determine whether or not a gene gets switched on to make the protein it encodes.

13 Aug 2013

Scientists present novel method to visualize how nuclear protein mobility changes following DNA damage

Understanding the cellular response to DNA strand breaks is crucial to decipher the mechanisms maintaining the integrity of our genome. In eukaryotic cells, the molecular events triggered by DNA damage are strongly influenced by the local chromatin environment surrounding the lesion. The ensuing DNA repair process, in turn, impacts on chromatin structure. In order to understand how these two fundamental processes are mutually connected, both chromatin rearrangements induced by DNA damage as well as DNA repair activity have to be visualized in living cells.

12 Aug 2013

Video Journal and Encyclopedia of GI Endoscopy now available on ScienceDirect

New open access title: Video Journal and Encyclopedia of GI Endoscopy (VJGIEN) now available on ScienceDirect. Elsevier, a world-leading provider of scientific, technical and medical information products and services, is pleased to announce the launch of Video Journal and Encyclopedia of GI Endoscopy (VJGIEN) - an open access video journal providing scientists and clinicians with state-of-the-art visual information of gastrointestinal (GI) pathologies and step-by-step demonstrations and the first of its kind in the field of gastrointestinal endoscopy.

12 Aug 2013

NW Bio receives decision to continue Phase III clinical trial on brain cancer in Germany

Northwest Biotherapeutics (NASDAQ: NWBO)(NW Bio), a biotechnology company developing non-toxic DCVax® personalized immune therapies for solid tumor cancers, announced today that it has received a decision from the German regulatory agency (the Paul Ehrlich Institute, or PEI) under which the Company's Phase III clinical trial will be able to proceed in Germany after the Company makes three modifications, none of which affect the body of the trial or the bases for seeking product approval.

12 Aug 2013

Wayne State professor publishes new book that covers advances in nano cell biology

A Wayne State University School of Medicine professor has published a book that covers new advances in nano cell biology, nano medicine and imaging modalities.

12 Aug 2013

Parents use bibliotherapy as a tool to help kids facing social issues

A new study out of the University of Cincinnati not only finds that parents feel responsible for taking action when their children struggle with social issues, but also that parents are influenced by their own childhood memories when it comes to dealing with their kids problems.

12 Aug 2013

Engaging in family-specific mental labor negatively affects well-being of mothers, not fathers

Although working mothers and fathers are almost as likely to think about family matters throughout the day, only for mothers is this type of mental labor associated with increased stress and negative emotions, according to new research to be presented at the 108th Annual Meeting of the American Sociological Association.

12 Aug 2013

Grandparent-grandchild relationship may have positive effects on both generations

A new study shows that grandparents and grandchildren have real, measurable effects on each other's psychological well-being long into grandchildren's adulthood.

12 Aug 2013

OGF-OGFr axis can be modulated in human triple-negative breast cancer cells to inhibit proliferation

Researchers at The Pennsylvania State University College of Medicine, led by Dr. Ian S. Zagon, have discovered that a novel biological pathway, the OGF-OGFr axis, can be modulated in human triple-negative breast cancer cells to inhibit proliferation. According to BreastCancer.org 1 in 8 women in the U.S. will develop invasive breast cancer and more than 39,000 deaths occur annually.

12 Aug 2013

Adolescents who have half-siblings with different father are more likely to use drugs

Adolescents who have half-siblings with a different father are more likely to have used drugs and had sex by age 15 than those who have only full siblings. That's according to new research from Karen Benjamin Guzzo, an assistant professor of sociology at Bowling Green State University, and Cassandra Dorius, an assistant professor of human development and family studies at Iowa State University.

12 Aug 2013

Specialized endocytocis play a crucial role in shaping cells themselves

The process cells use to 'swallow' up nutrients, hormones and other signals from their environment - called endocytosis - can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found.

12 Aug 2013

Study shows kids who overestimate their popularity display less aggression

Children who overestimate their popularity are less likely to be bullies than those who underestimate or hold more accurate assessments of their social standing, finds new research to be presented at the 108th Annual Meeting of the American Sociological Association.

12 Aug 2013

Genetically engineered proteins may be promising new tool for mapping brain cell activity

Scientists used fruit flies to show for the first time that a new class of genetically engineered proteins can be used to watch nerve cell electrical activity in live brains. The results, published in Cell, suggest these proteins may be a promising new tool for mapping brain cell activity in multiple animals and for studying how neurological disorders disrupt normal nerve cell signaling.

9 Aug 2013

Tubingen researchers resolve how a plant steroid hormone makes plants grow

If one wants to better understand how plants grow, one must analyse the chemistry of life in its molecular detail. Michael Hothorn from the Friedrich-Miescher-Laboratory of the Max Planck Society in T-bingen and his team are doing just that. Their latest work now reveals that a plant membrane receptor requires a helper protein to sense a growth-promoting steroid hormone and to transduce this signal across the cell membrane.

9 Aug 2013

Four genetic variants in non-small cell lung cancer patients help predict survival, treatment response

Researchers at the Moffitt Cancer Center have identified four inherited genetic variants in non-small cell lung cancer patients that can help predict survival and treatment response. Their findings could help lead to more personalized treatment options and improved outcomes for patients.

9 Aug 2013

Celgene's pomalidomide gets approval in UK for multiple myeloma

Celgene confirmed today that Pomalidomide Celgene▼ (pomalidomide), a new oral blood cancer therapy, has been granted Marketing Authorisation by the European Medicines Agency and is now available in the UK and Ireland.

9 Aug 2013

Cell News and Research

Growing up with siblings may provide some protection against divorce as adult

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Researchers explore potential of neural stem cells to repair brain damage

Researchers create an efficient technique to target and repair defective genes

Learning "grammar" helps determine whether gene gets switched on or not

Scientists present novel method to visualize how nuclear protein mobility changes following DNA damage

Video Journal and Encyclopedia of GI Endoscopy now available on ScienceDirect

NW Bio receives decision to continue Phase III clinical trial on brain cancer in Germany

Wayne State professor publishes new book that covers advances in nano cell biology

Parents use bibliotherapy as a tool to help kids facing social issues

Engaging in family-specific mental labor negatively affects well-being of mothers, not fathers

Grandparent-grandchild relationship may have positive effects on both generations

OGF-OGFr axis can be modulated in human triple-negative breast cancer cells to inhibit proliferation

Adolescents who have half-siblings with different father are more likely to use drugs

Specialized endocytocis play a crucial role in shaping cells themselves

Study shows kids who overestimate their popularity display less aggression

Genetically engineered proteins may be promising new tool for mapping brain cell activity

Tubingen researchers resolve how a plant steroid hormone makes plants grow

Four genetic variants in non-small cell lung cancer patients help predict survival, treatment response

Celgene's pomalidomide gets approval in UK for multiple myeloma

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