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Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

A team led by Pr. Marina Cavazzana conducted at Necker Children's Hospital, AP-HP and the Imagine Institute in October 2014 gene therapy in the context of a phase I clinical trial / II in a patient 13 years with severe sickle cell disease.

2 Mar 2017

Study provides insights into how cancer cells can evade FGFR inhibitors

A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has identified a mechanism by which cancer cells develop resistance to a class of drugs called fibroblast growth factor receptor (FGFR) inhibitors.

2 Mar 2017

BUSM researchers participate in five-year program to develop biomarkers for small vessel disease

To better predict, study and diagnose small vessel disease in the brain and its role in vascular contributions to cognitive impairment and dementia (VCID), Boston University School of Medicine has been selected to participate in MarkVCID, a consortium designed to accelerate the development of new and existing biomarkers for small vessel VCID.

2 Mar 2017

Study shows how ‘secondhand sugar’ can pass from mother to infant through breast milk

Add breast milk to the list of foods and beverages that contain fructose, a sweetener linked to health issues ranging from obesity to diabetes.

2 Mar 2017

New micro-pump technology may offer promising alternative to eye drops for glaucoma patients

It is no secret that the issues associated with current glaucoma medications can be problematic. Systemic medications carry the risk of side effects, while the current medical treatment of choice, eye drops, has its own drawbacks.

2 Mar 2017

Scientists reveal new mRNA method to deliver safe, cost-effective therapeutic antibodies

Using antibodies to treat disease has been one of the great success stories of early 21st-century medicine. Already five of the ten top-selling pharmaceuticals in the United States are antibody products. But antibodies are large, complex proteins that can be expensive to manufacture.

2 Mar 2017

Cigarette smoke blocks lung's self-healing that can lead to COPD

Smoke from cigarettes blocks self-healing processes in the lungs and consequently can lead to chronic obstructive pulmonary disease (COPD).

2 Mar 2017

Treating pregnant women for mild thyroid dysfunction provides no benefit, study finds

A large national study suggests that treating pregnant women for mildly low thyroid function does not improve the IQs of their babies or reduce preterm births or other negative outcomes.

2 Mar 2017

New wireless patch may help reduce migraine pain as well as drugs, study suggests

A preliminary study suggests that a new, wireless patch that you wear on your arm may help reduce migraine pain as well as drugs. The study is published in the March 1, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.

2 Mar 2017

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

A Japanese research group has discovered that a newly-identified autoimmune endocrine disease that leads to hypopituitarism is caused by thymomas (a type of tumor originating from the thymic gland).

2 Mar 2017

Study shows new drug as promising treatment option for difficult-to-treat rheumatoid arthritis patients

Between 3 and 5% of the population suffer from a form of inflammatory rheumatism. It affects approximately 250,000 - 400,000 people in Austria.

2 Mar 2017

Telephone-delivered collaborative care program effective in treating anxiety disorders

A telephone-delivered collaborative care program for treating panic and generalized anxiety disorders in primary care is significantly more effective than doctors' usual care at improving health-related quality of life, anxiety and mood symptoms, according to a new study led by researchers at the University of Pittsburgh School of Medicine.

2 Mar 2017

Gut bacteria impact intestinal and behavioural symptoms in IBS patients, study finds

Research from McMaster University has found that bacteria in the gut impacts both intestinal and behavioural symptoms in patients suffering from irritable bowel syndrome (IBS), a finding which could lead to new microbiota-directed treatments.

2 Mar 2017

Cholesterol-processing enzyme could be therapeutic target to stave off neurologic diseases

An enzyme that helps break down cholesterol may also be a therapeutic target to stave off neurologic diseases, including Alzheimer's and a rare genetic disorder, according to a new study published in the Journal of Biological Chemistry.

2 Mar 2017

AAD launches new campaign to raise awareness of impact of skin diseases

Citing a new study assessing the impact of skin disease on patients and the U.S. economy, the American Academy of Dermatology is launching a new campaign to raise awareness of the breadth of serious skin diseases that affect patients, as well as the critical role dermatologists play in an era of team-based health care.

2 Mar 2017

Immune-stimulating chemical found in tumors may help stop cancer growth

A chemical found in tumors may help stop tumor growth, according to a new study.

2 Mar 2017

Brains of adolescents with anorexia nervosa remain altered even after treatment, study finds

Even after weeks of treatment and considerable weight gain, the brains of adolescent patients with anorexia nervosa remain altered, putting them at risk for possible relapse, according to researchers at the University of Colorado Anschutz Medical Campus.

1 Mar 2017

$Study highlights potential tolerability of single fraction of HDR brachytherapy for localized prostate cancer$

Study highlights potential tolerability of single fraction of HDR brachytherapy for localized prostate cancer

Results from a new prospective clinical trial indicate that high-dose-rate (HDR) brachytherapy administered in a single, 19 Gray treatment may be a safe and effective alternative to longer courses of HDR treatment for men with localized prostate cancer.

1 Mar 2017

Highly prevalent gene variants in African Americans contribute to kidney disease

African Americans have a heightened risk of developing chronic and end-stage kidney disease. This association has been attributed to two common genetic variants - named G1 and G2 -- in APOL1, a gene that codes for a human-specific protein.

1 Mar 2017

Workers without paid sick leave less likely to receive preventive health care screenings, study finds

More than 20 million Americans have gained health insurance coverage through the Affordable Care Act and do not have to pay for 15 preventive screenings recommended by the U.S. Preventive Services Task Force.

1 Mar 2017

Medicine News and Research

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

Study provides insights into how cancer cells can evade FGFR inhibitors

BUSM researchers participate in five-year program to develop biomarkers for small vessel disease

Study shows how ‘secondhand sugar’ can pass from mother to infant through breast milk

New micro-pump technology may offer promising alternative to eye drops for glaucoma patients

Scientists reveal new mRNA method to deliver safe, cost-effective therapeutic antibodies

Cigarette smoke blocks lung's self-healing that can lead to COPD

Treating pregnant women for mild thyroid dysfunction provides no benefit, study finds

New wireless patch may help reduce migraine pain as well as drugs, study suggests

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

Study shows new drug as promising treatment option for difficult-to-treat rheumatoid arthritis patients

Telephone-delivered collaborative care program effective in treating anxiety disorders

Gut bacteria impact intestinal and behavioural symptoms in IBS patients, study finds

Cholesterol-processing enzyme could be therapeutic target to stave off neurologic diseases

AAD launches new campaign to raise awareness of impact of skin diseases

Immune-stimulating chemical found in tumors may help stop cancer growth

Brains of adolescents with anorexia nervosa remain altered even after treatment, study finds

Study highlights potential tolerability of single fraction of HDR brachytherapy for localized prostate cancer

Highly prevalent gene variants in African Americans contribute to kidney disease

Workers without paid sick leave less likely to receive preventive health care screenings, study finds

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Improving healthcare sustainability through carbon data

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