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NIH-funded study may help predict treatment response in older adults with depression

Treating depressed individuals and figuring out who will and won't respond to antidepressants is mostly trial and error — much to the frustration of patients and the health care providers who treat them.

11 Sep 2015

Intake of cocoa flavanols improves cardiovascular function, lowers blood pressure

Two recently published studies in the journals Age and the British Journal of Nutrition (BJN) demonstrate that consuming cocoa flavanols improves cardiovascular function and lessens the burden on the heart that comes with the ageing and stiffening of arteries.

11 Sep 2015

VEGF family biomarkers ‘promising’ tools for pulmonary hypertension diagnosis

Two members of the vascular endothelial growth factor family are highly specific and moderately sensitive for the presence of pulmonary hypertension, report researchers.

10 Sep 2015

World expert panel recommends routine brain health screening for adults older than 70

A panel of world experts in aging convened at Saint Louis University recommended that everyone 70 and older should have their memory and reasoning ability evaluated annually by a doctor or health care provider.

10 Sep 2015

MU researchers identify age-related cause of arterial dysfunction

With the world's elderly population expected to double by 2050, understanding how aging affects the body is an important focus for researchers globally. Cardiovascular disease, the No. 1 cause of death worldwide, often is associated with aging arteries that restrict blood flow. Now, University of Missouri researchers have identified an age-related cause of arterial dysfunction, a finding that could lead to future treatments for some forms of vascular disease.

9 Sep 2015

New study reveals pivotal role of miR-506 biomarker in gastric cancer

Gastric cancer poses a significant health problem in developing countries and is typically associated with late-stage diagnosis and high mortality. A new study in The American Journal of Pathology points to a pivotal role played by the biomarker microRNA (miR)-506 in gastric cancer.

8 Sep 2015

Sustainable irrigation strategies could increase health benefits of virgin olive oil

A team of researchers, that includes UPM, have confirmed that a part of the benefits of virgin olive oil is due to minority compounds that can be increased with sustainable irrigation strategies.

7 Sep 2015

Hutchison MediPharma achieves primary endpoint in POC Phase II study to treat NSCLC patients

Hutchison China MediTech Limited today announces that Hutchison MediPharma Limited ("HMP"), its drug R&D subsidiary, successfully achieved the primary endpoint in the second proof-of-concept ("POC") trial of fruquintinib in patients with advanced non-squamous non-small cell lung cancer ("NSCLC") in China.

4 Sep 2015

Children's Hospital Los Angeles receives $2 million to spur research on brain, spinal cord tumors

A life-changing event for a Los Angeles family has resulted in their funding an endowment to support The Kort Family Foundation Brain and Spinal Cord Tumor Research Program in the Division of Neurosurgery at Children's Hospital Los Angeles.

3 Sep 2015

Familial hypercholesterolemia patients can benefit from alirocumab drug

Alirocumab lowers cholesterol in patients with heterozygous familial hypercholesterolemia to levels unreachable with statins alone, according to results from four ODYSSEY trials presented at ESC Congress today.

2 Sep 2015

SLU scientist receives grant to solve blood-clotting mysteries

Last summer, SLU scientists made a breakthrough discovery about the way in which blood clots. Through X-ray crystallography, they solved the molecular structure of prothrombin, an important blood-clotting protein, revealing an unexpected, flexible role for a "linker" region that may be the key to developing better life-saving drugs.

1 Sep 2015

Preoperative statins linked to reductions in cardiac complications, mortality after noncardiac surgery

Preoperative statins are associated with a 17% reduction in cardiac complications and a 43% reduction in mortality after noncardiac surgery, according to results from the VISION Study presented for the first time today at ESC Congress by Dr Otavio Berwanger, director of the Research Institute HCor, Hospital do Coração (Heart Hospital) in São Paulo, Brazil.

1 Sep 2015

Pie Medical Imaging receives 2015 European Frost & Sullivan Award for Technology Leadership

Based on its recent analysis of the cardiovascular image management market, Frost & Sullivan recognizes Pie Medical Imaging (PMI) with the 2015 European Frost & Sullivan Award for Technology Leadership.

1 Sep 2015

Bioresorbable vascular scaffold shows similar safety, efficacy results compared to metal stent

A drug-eluting coronary stent, or "scaffold" made from bioresorbable material, showed similar efficacy and safety results compared to a metal stent in patients undergoing percutaneous coronary intervention (PCI), according to results of the ABSORB Japan study.

1 Sep 2015

Tissue adhesive porous films promote angiogenesis without using growth factors

A research group led by Tetsushi Taguchi, a MANA Scientist at the Biomaterials Unit, International Center for Materials Nanoarchitectonics (MANA), NIMS, has developed tissue adhesive porous films that promote angiogenesis (formation of new blood vessels) without using growth factors.

1 Sep 2015

STEMI study: Absorbable stents perform similarly to metallic stents

A drug-eluting coronary stent made of absorbable material performed similarly to the gold-standard metal one in a non-inferiority trial among patients with the more serious type of heart attack known as ST-segment elevation myocardial infarction (STEMI), according to results of the ABSORB STEMI TROFI II trial.

1 Sep 2015

Abbott reports positive results of ABSORB Japan study comparing efficacy of fully dissolving heart stent to XIENCE

Abbott (NYSE: ABT) announced today positive one-year clinical results from ABSORB Japan, a multi-center, randomized trial comparing the safety and effectiveness of Abbott's fully dissolving Absorb™ heart stent to XIENCE ®, Abbott's market-leading, permanent drug eluting stent.

1 Sep 2015

Elderly patients can benefit from new, minimally invasive surgery for aortic valve replacement

Select patients age 90 years and older with aortic stenosis (AS) can benefit from a relatively new, minimally invasive surgery for aortic valve replacement, according to an article in the September 2015 issue of The Annals of Thoracic Surgery.

1 Sep 2015

Additional electrical isolation of left atrial appendage could improve freedom from AF

In patients with long-standing persistent atrial fibrillation (AF) despite standard treatment, additional electrical isolation of an area called the left atrial appendage (LAA) can improve freedom from AF without increasing complications, results of the BELIEF study show.

31 Aug 2015

Prolonged television watching associated with twice the risk of fatal pulmonary embolism

Prolonged television watchers have a higher risk of fatal pulmonary embolism, a condition associated with long haul flights, reveals research presented at ESC Congress today by Mr Toru Shirakawa, public health research fellow in the Department of Social Medicine at Osaka University in Japan.

31 Aug 2015

Vascular News and Research

NIH-funded study may help predict treatment response in older adults with depression

Intake of cocoa flavanols improves cardiovascular function, lowers blood pressure

VEGF family biomarkers ‘promising’ tools for pulmonary hypertension diagnosis

World expert panel recommends routine brain health screening for adults older than 70

MU researchers identify age-related cause of arterial dysfunction

New study reveals pivotal role of miR-506 biomarker in gastric cancer

Sustainable irrigation strategies could increase health benefits of virgin olive oil

Hutchison MediPharma achieves primary endpoint in POC Phase II study to treat NSCLC patients

Children's Hospital Los Angeles receives $2 million to spur research on brain, spinal cord tumors

Familial hypercholesterolemia patients can benefit from alirocumab drug

SLU scientist receives grant to solve blood-clotting mysteries

Preoperative statins linked to reductions in cardiac complications, mortality after noncardiac surgery

Pie Medical Imaging receives 2015 European Frost & Sullivan Award for Technology Leadership

Bioresorbable vascular scaffold shows similar safety, efficacy results compared to metal stent

Tissue adhesive porous films promote angiogenesis without using growth factors

STEMI study: Absorbable stents perform similarly to metallic stents

Abbott reports positive results of ABSORB Japan study comparing efficacy of fully dissolving heart stent to XIENCE

Elderly patients can benefit from new, minimally invasive surgery for aortic valve replacement

Additional electrical isolation of left atrial appendage could improve freedom from AF

Prolonged television watching associated with twice the risk of fatal pulmonary embolism

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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