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New research on Alzheimer's

Advancing age is a major risk factor for Alzheimer's disease and is associated with build- up of the peptide amyloid β in the brain. New research published in BioMed Central's open access journal Fluids and Barriers of the CNS shows that removal of amyloid β from the brain depends on vitamin D and also on an age-related alteration in the production of transporter proteins which move amyloid β in and out of the brain.

11 Jul 2011

Scientists unravel how memories are 'read out' in fly brain

What happens if you cannot recall your memory correctly? You are able to associate and store the name and face of a person, yet you might be unable to remember them when you meet that person. In this example, the recall of the information is temporarily impaired. How such associative memories are "read out" in the brain remains one of the great mysteries of modern neurobiology.

11 Jul 2011

Positive top-line results from alemtuzumab Phase 3 trial on multiple sclerosis

Sanofi and its subsidiary Genzyme announced today positive top-line results from CARE-MS I, the first of two randomized, Phase 3 clinical trials comparing the investigational drug alemtuzumab to the approved multiple sclerosis therapy Rebif in patients with relapsing-remitting multiple sclerosis.

11 Jul 2011

Scientists convert brain cells into cardiomyocytes

For the past decade, researchers have tried to reprogram the identity of all kinds of cell types. Heart cells are one of the most sought-after cells in regenerative medicine because researchers anticipate that they may help to repair injured hearts by replacing lost tissue.

11 Jul 2011

Life Technologies introduces new India Distribution Center

Life Technologies Corporation announced today that it has launched a regional distribution hub in India to address strong customer demand in the South Asia region.

11 Jul 2011

Research targets malignant glioma stem cells

Cleveland Clinic researchers have identified a cellular pathway that cancer stem cells use to promote tumor growth in malignant glioma, an aggressive brain tumor.

11 Jul 2011

Scientists discover seven new gene variants that increase risk of prostate cancer

Cancer Research UK-funded scientists have taken a further step to identifying men at a greater risk of prostate cancer with the discovery of seven new variants in the human genome that increase the chances of developing the disease.

11 Jul 2011

Scientists probe 'atlastin,' a protein linked to hereditary spastic paraplegia

New research from Rice University and Italy's Eugenio Medea Scientific Institute is yielding clues about hereditary spastic paraplegia (HSP), a group of inherited neurological disorders that affect about 20,000 people in the United States.

11 Jul 2011

Brigham and Women's Hospital receives NIH Program of Excellence in Glycosciences award

The laboratory of Robert Sackstein, MD, PhD, of the Dermatology Department at Brigham and Women's Hospital (BWH), has been granted a prestigious Program of Excellence Award from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH), to support investigations in glycobiology: the discipline which studies how sugars direct biologic processes.

8 Jul 2011

Onconova, SymBio enter commercialization collaboration for rigosertib in Japan and Korea

Onconova Therapeutics, Inc., and SymBio Pharmaceuticals Limited announced today that they will collaborate to develop and commercialize rigosertib in Japan and Korea. Onconova is conducting late-stage clinical trials with rigosertib (ON 01910.Na) in the U.S., Europe and India for the treatment of Myelodysplastic Syndromes (MDS) and solid tumors.

8 Jul 2011

Common cell pathway could lead to new treatments for autoimmune diseases and cancer

A discovery by University of Alabama at Birmingham researchers about a how a common cell pathway that helps regulate cell survival and production is turned on could lead to new treatments for autoimmune diseases and cancer.

8 Jul 2011

AJMS summarizes developments related to idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a common and severe lung disease of unknown cause and with no proven therapies. But researchers are pushing forward in investigating new clues to the development and effective treatment of IPF, according to a special symposium presented in The American Journal of the Medical Sciences (AJMS), official journal of the Southern Society for Clinical Investigation (SSCI).

8 Jul 2011

Scientists discover mechanism that enables developing cancer cells to sustain abnormal growth

Scripps Research Institute scientists have discovered a basic mechanism that can enable developing cancer cells to sustain abnormal growth. The finding is expected to lead to the targeting of this mechanism with drugs and diagnostic techniques.

8 Jul 2011

Merck decides not to advance IMO-2055 development for squamous cell carcinoma of the head and neck

Idera Pharmaceuticals today provides an update on the clinical development of IMO-2055 (EMD 1201081), a TLR9 agonist for cancer treatment being developed by Merck KGaA, Darmstadt, Germany, under its collaboration with Idera.

8 Jul 2011

New human syndrome features craniosynostosis, maxillary hyperplasia, delayed tooth eruption, extra teeth

Researchers at the University of Helsinki, Finland, have described a new, recessively inherited human syndrome featuring craniosynostosis, maxillary hyperplasia, delayed tooth eruption and extra teeth. The researchers also identified causative mutations in a gene IL11RA.

8 Jul 2011

Pediatricians debunk pearls of medical wisdom

Don't Cross Your Eyes-They'll Get Stuck that Way!, a new book by myth-fighting Indiana University School of Medicine pediatricians Aaron Carroll, M.D., M.S., and Rachel Vreeman, M.D., M.S., debunks the pearls of medical wisdom that many people and even their physicians believe are true. Be prepared to revise your thinking; no, an apple a day won't keep the doctor away and no, warm milk won't help you sleep.

8 Jul 2011

Transplants with half-matched bone marrow or cord blood are comparable to fully matched tissue

Identifying a suitable donor for leukemia and lymphoma patients who need bone marrow transplants may be far easier now that results of two clinical trials show transplant results with half-matched bone marrow or umbilical cord blood are comparable to fully matched tissue, thanks in large part to the availability of effective antirejection drugs and special post-transplant chemotherapy.

8 Jul 2011

New technique may help scientists probe mysteries of many different stem cells

Researchers at the Salk Institute have been able to genetically incorporate "unnatural" amino acids, such as those emitting green fluorescence, into neural stem cells, which then differentiate into brain neurons with the incandescent "tag" intact.

8 Jul 2011

Mesenchymal stem cells protect and heal

A stem cell that can morph into a number of different tissues is proving a natural protector, healer and antibiotic maker, researchers at Case Western Reserve University and their peers have found.

8 Jul 2011

Autologous adult stem cells reduce frequency of angina episodes

New research published online today in Circulation Research found that injections of adult patients' own CD34+ stem cells reduced reports of angina episodes and improved exercise tolerance time in patients with chronic, severe refractory angina (severe chest discomfort that did not respond to other therapeutic options).

From Baxter International Inc. 8 Jul 2011

Cell News and Research

New research on Alzheimer's

Scientists unravel how memories are 'read out' in fly brain

Positive top-line results from alemtuzumab Phase 3 trial on multiple sclerosis

Scientists convert brain cells into cardiomyocytes

Life Technologies introduces new India Distribution Center

Research targets malignant glioma stem cells

Scientists discover seven new gene variants that increase risk of prostate cancer

Scientists probe 'atlastin,' a protein linked to hereditary spastic paraplegia

Brigham and Women's Hospital receives NIH Program of Excellence in Glycosciences award

Onconova, SymBio enter commercialization collaboration for rigosertib in Japan and Korea

Common cell pathway could lead to new treatments for autoimmune diseases and cancer

AJMS summarizes developments related to idiopathic pulmonary fibrosis

Scientists discover mechanism that enables developing cancer cells to sustain abnormal growth

Merck decides not to advance IMO-2055 development for squamous cell carcinoma of the head and neck

New human syndrome features craniosynostosis, maxillary hyperplasia, delayed tooth eruption, extra teeth

Pediatricians debunk pearls of medical wisdom

Transplants with half-matched bone marrow or cord blood are comparable to fully matched tissue

New technique may help scientists probe mysteries of many different stem cells

Mesenchymal stem cells protect and heal

Autologous adult stem cells reduce frequency of angina episodes

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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